Pancreatic size and fat content in diabetes: A systematic review and meta-analysis of imaging studies.

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Annotation Summary

Term Occurence Count Dictionary
Insulin 2 endocrinologydiseasesdrugs
diabetes mellitus 1 endocrinologydiseases
hyperglycemia 1 endocrinologydiseases
obesity 2 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Insulin 3059 studies have demonstrated reduced pancreas size in both type 1 [[6]] and type 2 diabetic subjects [[7]]. Insulin deficiency and the lack of a trophic effect of insulin on acinar cells[[6]]as well as the chronic inflammation
Insulin 26677 pancreatic fat content is increased in T2DM patients, which may reflect a paracrine effect of insulin. Insulin resistance causes increased insulin secretion by beta cells, and the higher local insulin concentration
Select Disease Character Offset Disease Term Instance
diabetes mellitus 2612 AvailabilityAll relevant data are within the paper (see Table 1).IntroductionThe pancreas plays a key role in diabetes mellitus , a progressive disease characterized by chronic hyperglycemia [[1]] in the context of insulin resistance
hyperglycemia 2678 1).IntroductionThe pancreas plays a key role in diabetes mellitus, a progressive disease characterized by chronic hyperglycemia [[1]] in the context of insulin resistance [[2]] and/or beta cell dysfunction and death [[3]]. Beta
obesity 4205 issue.Interestingly, CT and MRI are widely used to measure liver steatosis [[21], [22]], which is closely related to obesity and diabetes [[22]]. More recently, imaging protocols have produced accurate non-invasive measurements
obesity 26263 pancreas of diabetic patients as compared to healthy subjects [[24]]. Furthermore, in T2DM patients, obesity was associated with lower pancreatic density evaluated by CT, indicating higher pancreatic fat content

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