GASTRIC NEUROENDOCRINE TUMOR: REVIEW AND UPDATE.

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Annotation Summary

Term Occurence Count Dictionary
everolimus 1 endocrinologydiseasesdrugs
multiple endocrine neoplasia 1 endocrinologydiseases
neuroendocrine tumor 7 endocrinologydiseases
sorafenib 1 endocrinologydiseasesdrugs
sunitinib 1 endocrinologydiseasesdrugs
Zollinger-Ellison syndrome 1 endocrinologydiseases
carcinoid 3 endocrinologydiseases
cyclophosphamide 1 endocrinologydiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

Review

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Select Drug Character Offset Drug Term Instance
cyclophosphamide 12490 disease, systemic therapy with cytotoxic chemotherapy (streptozocin combined with 5-fluorouracil or cyclophosphamide , doxorubicin mono drug or with 5-fluorouracil, dacarbazine or temozolamide, oxaliplatin with capecitabine
everolimus 12726 5-flurouracil with leucovorin) or molecular targeted agents (bevacizumab, sorafenib, sunitinib, pazopanib and everolimus ) can be introduced. The goal is to keep the disease stable, with a small gain in progression-free survival,
sorafenib 12690 oxaliplatin with capecitabine or 5-flurouracil with leucovorin) or molecular targeted agents (bevacizumab, sorafenib , sunitinib, pazopanib and everolimus) can be introduced. The goal is to keep the disease stable, with
sunitinib 12701 capecitabine or 5-flurouracil with leucovorin) or molecular targeted agents (bevacizumab, sorafenib, sunitinib , pazopanib and everolimus) can be introduced. The goal is to keep the disease stable, with a small gain
Select Disease Character Offset Disease Term Instance
Zollinger-Ellison syndrome 4900 (pH≥7)[22],[32].Type IIType II lesions are caused by gastrinomas (gastrin-producing tumors), also known as Zollinger-Ellison syndrome . In most cases, the patient has multiple endocrine neoplasia type I (MEN-1) and should be investigated
carcinoid 1059 using the following databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid , gastric neuroendocrine tumor, treatment. From the selected articles, 38 were included in this review.
carcinoid 3076 using the following databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid , gastric neuroendocrine tumor, treatment. Articles in English and Portuguese were considered.RESULTSClassification
carcinoid 6687 endoscopy with biopsy, observing a single lesion in normal gastric mucosa (Figure 2B). Although rare, carcinoid syndrome (due to the presence of liver metastasis) can be the initial manifestation.Type IVIt is worth
multiple endocrine neoplasia 4959 (gastrin-producing tumors), also known as Zollinger-Ellison syndrome. In most cases, the patient has multiple endocrine neoplasia type I (MEN-1) and should be investigated with serum sequencing for MEN1 gene[16].The frequency of type
neuroendocrine tumor 601 (epub-ppub): /2017Publication date (ppub): /2017AbstractABSTRACTIntroduction: The frequency of gastric neuroendocrine tumor s is increasing. Reasons are the popularization of endoscopy and its technical refinements. Despite this,
neuroendocrine tumor 826 they are still poorly understood and have complex management. Aim: Update the knowledge on gastric neuroendocrine tumor and expose the future perspectives on the diagnosis and treatment of this disease. Method: Literature
neuroendocrine tumor 1078 databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid, gastric neuroendocrine tumor , treatment. From the selected articles, 38 were included in this review. Results: Gastric neuroendocrine
neuroendocrine tumor 1189 neuroendocrine tumor, treatment. From the selected articles, 38 were included in this review. Results: Gastric neuroendocrine tumor s are classified in four clinical types. Correct identification of the clinical type and histological
neuroendocrine tumor 1410 grade is fundamental, since treatment varies accordingly and defines survival. Conclusion: Gastric neuroendocrine tumor s comprise different subtypes with distinct management and prognosis. Correct identification allows for
neuroendocrine tumor 1651 therapy. Further studies will clarify the diseases biology and improve its treatment. INTRODUCTIONGastric neuroendocrine tumor s (gNETs) are neoplasms derived from the enterochromaffin-like cells (ECL cells) of the gastric mucosa.
neuroendocrine tumor 3095 databases: Medline/PubMed, Cochrane Library and SciELO. Search terms were: gastric carcinoid, gastric neuroendocrine tumor , treatment. Articles in English and Portuguese were considered.RESULTSClassification and diagnosisType

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