Fructose Consumption in the Development of Obesity and the Effects of Different Protocols of Physical Exercise on the Hepatic Metabolism

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Term Occurence Count Dictionary
Insulin 2 endocrinologydiseasesdrugs
glucose intolerance 1 endocrinologydiseases
hyperglycemia 1 endocrinologydiseases
hypertriglyceridemia 1 endocrinologydiseases
metabolic syndrome 4 endocrinologydiseases
obesity 23 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Insulin 50891 FoxO1: Forkhead box protein 01; Fructose-1P: Fructose 1-Phosphate; GLUT2: Glucose Transporter 2; IR: Insulin Receptor; IRS-1: Insulin Receptor Substrate 1; JNK-1: C-Jun-N terminal kinase-1; NAFLD: Non-Alcoholic
Insulin 50916 protein 01; Fructose-1P: Fructose 1-Phosphate; GLUT2: Glucose Transporter 2; IR: Insulin Receptor; IRS-1: Insulin Receptor Substrate 1; JNK-1: C-Jun-N terminal kinase-1; NAFLD: Non-Alcoholic Fat Liver Disease; PEPCK:
Select Disease Character Offset Disease Term Instance
glucose intolerance 35251 [[102]], using the same intervention, observed that animals who received a fructose solution presented glucose intolerance and increased adiposity; however, the practice of moderate aerobic exercise was effective to attenuate
hyperglycemia 49965 biodisponibility also activates SIRT-Dependent deacetylase of FoxO1 contributing to gluconeogenesis and hyperglycemia . Fructose-1P upregulates PGC-1β expression by promoting lipogenesis through SREBP1c activation. The
hypertriglyceridemia 50208 carbon chains for the synthesis of triglycerides, diacilglycerides, and VLDL cholesterol contributing to hypertriglyceridemia , hepatic insulin resistance, and dyslipidemia. Sub products of fructose target other tissues, leading
metabolic syndrome 2843 beverages rich in fructose is directly related to the development of obesity and its consequences, such as metabolic syndrome [[1],[2],[3]]. Concomitant with the increased incidence and prevalence of obesity and metabolic syndrome,
metabolic syndrome 2948 metabolic syndrome [[1],[2],[3]]. Concomitant with the increased incidence and prevalence of obesity and metabolic syndrome , the consumption of fructose has increased around 30% in the last 40 years [[4]]. More specifically,
metabolic syndrome 3636 for this reason obesity happens to be considered one of the major risk factors for the development of metabolic syndrome and, consequently, is listed as one of the most serious problems in relation to quality of life [[6]].
metabolic syndrome 37162 Its Complicatons: The Role of Strength ExerciseAlthough we are reaching a century of publications on metabolic syndrome related to aerobic exercise, the same does not apply to strength exercise. In 1984, Miller and colleagues
obesity 1373 consumption has been growing exponentially and, concomitant with this, the increase in the incidence of obesity and associated complications has followed the same behavior. Studies indicate that fructose may be a
obesity 2805 EnemyThe high consumption of sugary beverages rich in fructose is directly related to the development of obesity and its consequences, such as metabolic syndrome [[1],[2],[3]]. Concomitant with the increased incidence
obesity 2936 such as metabolic syndrome [[1],[2],[3]]. Concomitant with the increased incidence and prevalence of obesity and metabolic syndrome, the consumption of fructose has increased around 30% in the last 40 years [[4]].
obesity 3550 harmful effects on the organism through the secretion of various types of adipokines, and for this reason obesity happens to be considered one of the major risk factors for the development of metabolic syndrome and,
obesity 4001 [[7]]. With that in mind, because fructose consumption is strongly associated with the development of obesity , studies aimed at evaluating its role in the development of obesity are of paramount importance for
obesity 4069 associated with the development of obesity, studies aimed at evaluating its role in the development of obesity are of paramount importance for a better understanding of the development process of obesity.A recent
obesity 4162 development of obesity are of paramount importance for a better understanding of the development process of obesity .A recent meta-analysis found that consumption of fructose-rich beverages leads to increased body weight
obesity 5400 becoming obese during adulthood [[12]], thereby listing fructose as an important sugar in the genesis of obesity . Therefore, this article aimed to review the current literature to clarify how high fructose consumption
obesity 5920 PubMed (Medline), using the following descriptors and their combinations: fructose, high fructose, obesity , aerobic exercise, endurance exercise, aerobic training, endurance training, strength exercise, resistance
obesity 6747 Intake and Its Consequences on Metabolic Health3.1. Animal EvidenceAs previously discussed, the rates of obesity and fructose consumption are following the same pattern; thus, several studies were conducted to understand
obesity 7525 that high fructose consumption might lead to accumulation of adipose tissue, systemic inflammation, obesity , oxidative stress, and consequently insulin resistance in different tissues [[15],[16],[17],[18]]. Furthermore,
obesity 8755 insulin resistance [[16]].Furthermore, high fructose consumption may contribute to the development of obesity and metabolic complications, since it affects the central nervous system and might disturb hunger and
obesity 10712 which used fructose-rich sweeteners had a higher incidence of diabetes, even though the incidence of obesity and the total amount of sugars ingested did not increase. Recently, Lin and colleagues [[26]] carried
obesity 15160 foods containing caloric sweeteners [[34]]. While efforts to combat the development and treatment of obesity are rising, food production containing fructose, sucrose, or HCFs is increasing quickly. Currently,
obesity 15656 led several research groups to identify the intake of this nutrient as the main engine of the current obesity pandemic [[36],[37]].5. Sweet PoisonFound in several processed foods, fructose is usually either bonded
obesity 16460 transporters [[39]]. This characteristic is extremely important for understanding the pathogenesis of obesity . While glucose triggers the release of insulin by pancreatic beta cells, fructose is not able to do
obesity 17461 injection had the opposite effect [[45]]. These findings explain in part the increased prevalence of obesity in individuals who consume this nutrient in the form of sugary drinks or industrialized foods [[11]].
obesity 26821 obesogenic stimuli from nutritional factors, epidemiological studies also show that the genesis of obesity in contemporary society is also linked to the progressive decrease in the time available for the practice
obesity 32134 in obese animals [[91]], which is essential to improve the systemic inflammatory status promoted by obesity . Notably, when hypertrophied, adipose tissue is responsible for the secretion of a series of proteins
obesity 33249 the animals treated with a standard diet. However, animals that performed aerobic exercise during the obesity induction period had a reduction in the development of NAFLD. Similar results were found by Shen and
obesity 38272 showed evidence on the relationship of strength training with adiposity control and, consequently, obesity . After 16 weeks of exercise performed three times per week, the authors observed that although the body
obesity 39505 have begun to suggest strength exercise as an important strategy for the prevention and treatment of obesity [[114],[115],[116]] and in one of these studies Schmitz and colleagues [[115]] found positive results
obesity 47876 may be an important strategy for combating insulin resistance and oxidative stress associated with obesity , but more studies are needed to fully understand controls of exercise variables, such as exercise intensity

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