Role of the Enterocyte in Fructose-Induced Hypertriglyceridaemia

Existing Reviews

Please note, new claims can take a short while to show up.

No claims yet.

Annotation Summary

Term Occurence Count Dictionary
metabolic syndrome 2 endocrinologydiseases
obesity 1 endocrinologydiseases
rosiglitazone 1 endocrinologydiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.


Having read the paper, please pick a pair of statements from the paper to indicate that a drug and disease are related.

Select Drug Character Offset Drug Term Instance
rosiglitazone 21799 signalling [[74]]. This was supported by a subsequent study, where sensitisation of FFIR hamsters with rosiglitazone ameliorated TRL apoB48 over-production by 50% in cultured enterocytes [[75]]. Further work indicated
Select Disease Character Offset Disease Term Instance
metabolic syndrome 3807 This has been demonstrated in a hamster model of insulin resistance [[18]], as well as in men with metabolic syndrome (MetS) [[19]]. The hydrolysis of CM and VLDL in the circulation by lipoprotein lipase (LPL) and hepatic
metabolic syndrome 31752 al. (2013) [[19]] utilised the protocol to demonstrate an increased CM-TG concentration in men with metabolic syndrome , compared to lean individuals, which was due to an enhanced CM-TG production rate, with no difference
obesity 34343 fructose content of the diet (isocaloric substitution with starch) has beneficial effects in children with obesity and MetS, including reductions in fasted TG, total apoB, apoC-III and LDL cholesterol levels, as well

You must be authorized to submit a review.