Opuntia spp.: Characterization and Benefits in Chronic Diseases.

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Term Occurence Count Dictionary
metabolic syndrome 4 endocrinologydiseases
obesity 20 endocrinologydiseases
diabetes mellitus 1 endocrinologydiseases
hyperglycemia 1 endocrinologydiseases

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diabetes mellitus 28533 atherosclerotic lesion development and subsequent cardiovascular diseases.4.2. Opuntia spp. in DiabetesType 2 diabetes mellitus (T2DM) is a multifactorial disease including genetic determinants of individual susceptibility and environmental
hyperglycemia 31709 diabetes [[92]]. Opuntia spp. may exert an inhibitory effect on the oxidative environment generated by hyperglycemia , via their antioxidant components, and as suggested by a recent report by Berraaouan et al. [[93]] who
metabolic syndrome 22364 modifications were observed on HDL and triglycerides [[59]]. Likewise, the consumption by women affected with metabolic syndrome , of dried leaves from O. ficus-indica as dietary supplement, showed a rapid increase in circulating
metabolic syndrome 40335 beneficial food in their diet as a way to improve the biochemical and clinical abnormalities associated with metabolic syndrome [[108]]. To achieve the potential benefits associated with the concept of local beneficial food, it
metabolic syndrome 41274 could be of beneficial interest in weight loss and possibly in dealing with chronic diseases such as metabolic syndrome .4.4. Opuntia spp. in CancerNumerous studies have demonstrated the cytotoxic effects of various parts
metabolic syndrome 50924 healthy nutritional sources for preventing chronic diseases such as diabetes, cardiovascular diseases, metabolic syndrome , obesity, or aging, as well as infectious or neurodegenerative diseases. Since several years, scientific
obesity 867 medicine for their nutritional properties and their benefit in chronic diseases, particularly diabetes, obesity , cardiovascular diseases, and cancer. These plants are largely distributed in America, Africa, and the
obesity 2679 been used for centuries as food resources and in folk medicine for the treatment of chronic diseases ( obesity , cardiovascular and inflammatory diseases, diabetes, and gastric ulcer) and many other illnesses [[1]].
obesity 20014 of various Opuntia spp. in the development of atherosclerosis and cardiovascular diseases, diabetes, obesity , and cancer.4.1. Opuntia spp. in Cardiovascular DiseasesAtherosclerosis and its related cardiovascular
obesity 20759 reported in Western countries, that is, hypertension, high cholesterol levels, smoking, diabetes, and obesity [[55], [56]]. Interestingly, CAD and risk factors such as diabetes were rare in Mexico before the second
obesity 32257 Opuntia spp. in ObesityObesity is becoming a major public health concern all over the world. Worldwide obesity has more than doubled since 1980 with approximately 66 million obese individuals in the world [[94]].
obesity 32371 more than doubled since 1980 with approximately 66 million obese individuals in the world [[94]]. The obesity prevalence has increased significantly as a result of rapid urbanization and improvement in socioeconomic
obesity 32526 result of rapid urbanization and improvement in socioeconomic conditions. In Mexico, the prevalence of obesity in adults is 32% (with a higher prevalence in females) and is about 15% in children. Mexico faces a
obesity 32722 Mexico faces a challenging situation with one of the highest and most rapidly increasing prevalence of obesity . Thus, researchers, clinicians, and people looking to reduce body weight are always in search of solutions.The
obesity 32865 people looking to reduce body weight are always in search of solutions.The complex pathogenesis of obesity indicates the need of different intervention strategies to confront this problem with a simple drug
obesity 33507 increased during the last decade. This demand clearly indicates that medicinal plants for the treatment of obesity represent a current topic of interest. O. ficus-indica fruits, stems, seeds, and cladodes have been
obesity 34748 preadipocytes into adipocytes. Adipocyte dysfunction is strongly associated with the development of obesity . Many studies have shown that Opuntia extracts such as the flavonoid kaempferol or isorhamnetin can
obesity 35181 which plant extracts could interfere.4.3.2. Animal ModelsThe use of animal models with diet-induced obesity helped to evaluate the nutritional values and some biological parameters of cactus seed supplements
obesity 35677 the serum lipid profile and glucose, linked with beneficial effects on atherosclerosis, diabetes, and obesity [[99], [100]]. It exerts a favorable impact on insulin sensitivity through the regulation of genes involved
obesity 36125 [[103]]. To determine the metabolic effect of an O. ficus-indica extract on a mouse model of diet-induced obesity [[104]], the extract was added to a high-fat diet and administered to mice for 12 weeks. Mice fed with
obesity 36598 ficus-indica extract prevented the development of metabolic abnormalities associated with diet-induced obesity [[104]]. Thus, the use of different animal models provided many clues to the potential effects of Opuntia
obesity 36922 suggesting that cactus pears, given in different ways in the diet, could be efficient in human treatment of obesity .4.3.3. Clinical TrialsAntiobesity agents obtained from natural products are gaining more and more interest
obesity 36956 different ways in the diet, could be efficient in human treatment of obesity.4.3.3. Clinical TrialsAnti obesity agents obtained from natural products are gaining more and more interest in the scientific community,
obesity 40160 known for a long time to have beneficial medical properties. Indeed, individuals at risk for diabetes, obesity , or cardiovascular diseases will prefer to include local, beneficial food in their diet as a way to
obesity 40607 genetic variation of the population as nutrigenetics [[108]].Finally, in many countries, these “anti obesity agents” are marked as food supplements, which are exempted of strict licensing regulations routinely
obesity 50944 sources for preventing chronic diseases such as diabetes, cardiovascular diseases, metabolic syndrome, obesity , or aging, as well as infectious or neurodegenerative diseases. Since several years, scientific research

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