Platelets, diabetes and myocardial ischemia/reperfusion injury.

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Term Occurence Count Dictionary
diabetes mellitus 2 endocrinologydiseases
hyperlipidemia 1 endocrinologydiseases
metabolic syndrome 1 endocrinologydiseases
obesity 2 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Select Disease Character Offset Disease Term Instance
diabetes mellitus 1906 treatment of comorbidities, including diabetes, with appropriate medications are necessary. Type 2 diabetes mellitus (T2DM) is an expanding global pandemia characterized by a very high cardiovascular risk [[1], [2]] and
diabetes mellitus 19580 size by cardioprotective interventions [[61]]. The increased susceptibility to IRI in the setting of diabetes mellitus is due to several mechanisms, including alteration at mitochondrial level, altered production of ROS
hyperlipidemia 10283 cardiovascular risk profile, because of one or more comorbidities, such as diabetes, hypertension and/or hyperlipidemia , need early detection and appropriate therapies.In primary prevention of cardiovascular events in T2DM
metabolic syndrome 32562 However, recently, CHE has been identified as an adipokine associated with obesity, insulin resistance and metabolic syndrome [[104]]. Several cell types, including adipocytes and vascular smooth muscle cells produce CHE as a
obesity 32530 receptor1 (CMKLR1 or ChemR23). However, recently, CHE has been identified as an adipokine associated with obesity , insulin resistance and metabolic syndrome [[104]]. Several cell types, including adipocytes and vascular
obesity 33163 [[108]]. Thus, given its dual role, CHE deserves to be studied as a possible metabo-inflammatory player in obesity -related disorders, such as T2DM and CVD.Fig. 3Among the factors released by platelets, some have double

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