In middle-aged and old obese patients, training intervention reduces leptin level: A meta-analysis

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Term Occurence Count Dictionary
Insulin 2 endocrinologydiseasesdrugs
diabetes mellitus 1 endocrinologydiseases
metabolic syndrome 1 endocrinologydiseases
obesity 8 endocrinologydiseases
type 2 diabetes mellitus 1 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Insulin 24603 2Training-induced improvement in parameters of carbohydrate metabolism.StudySubgroupBaseline metabolic stateGlucose Insulin Fatouros et al. 2005 (36)Training group 1 (6-month, light-intensity, resistance)non-diabeticfasting*HOMA*Training
Insulin 39669 metabolism and insulin levelTraining also led to some improvement in parameters of carbohydrate metabolism. Insulin levels were mainly affected, glucose levels improved to a lesser extent [[36]–[45], [48]–[50]] (Table
Select Disease Character Offset Disease Term Instance
diabetes mellitus 4479 epidemic increases morbidity and mortality due to consequent cardiometabolic disorders including type 2 diabetes mellitus [[3], [4]], hypertension and coronary heart disease [[5]], atherosclerosis and ischemic stroke [[6]]
metabolic syndrome 5197 accumulation in obesity [[12]]. Hyperleptinemia is also an important etiological factor of consequent cardio metabolic syndrome and numerous inflammatory disorders [[12], [13], [17], [18]]. Additionally, its involvement in a number
obesity 1856 8/2017Publication date (collection): /2017AbstractBackgroundLeptin is one of the major adipokines in obesity that indicates the severity of fat accumulation. It is also an important etiological factor of consequent
obesity 2053 factor of consequent cardiometabolic and autoimmune disorders. Aging has been demonstrated to aggravate obesity and to induce leptin resistance and hyperleptinemia. Hyperleptinemia, on the other hand, may promote
obesity 2578 aimed to review the literature on the effects of training intervention on peripheral leptin level in obesity during aging, in order to evaluate the independent efficacy of this method. In the studies that were
obesity 4367 in modern societies due to our increasingly sedentary lifestyle and imbalanced dietary choices. This obesity epidemic increases morbidity and mortality due to consequent cardiometabolic disorders including type
obesity 5105 [[12]–[17]].Leptin is one of the major adipokines, its increased level indicates the severity of fat accumulation in obesity [[12]]. Hyperleptinemia is also an important etiological factor of consequent cardiometabolic syndrome
obesity 5710 development of age-associated cardiometabolic abnormalities [[23]] and autoimmune diseases [[18]].Therefore, obesity - and/or age-related hyperleptinemia is not simply an indicator of metabolic abnormalities, but it is
obesity 7607 on the effects of physical training on peripheral leptin level as indicator of metabolic health in obesity during aging. Our objective was to evaluate the independent efficacy of this intervention on peripheral
obesity 8700 strength' OR 'muscle power' OR 'muscle force' OR exercise OR training) AND (overweight OR obese OR obesity ). This search identified 1207 records. Similar searches were conducted in Embase and Cochrane Library
type 2 diabetes mellitus 4472 obesity epidemic increases morbidity and mortality due to consequent cardiometabolic disorders including type 2 diabetes mellitus [[3], [4]], hypertension and coronary heart disease [[5]], atherosclerosis and ischemic stroke [[6]]

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