Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?

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Term Occurence Count Dictionary
diabetes mellitus 3 endocrinologydiseases
hyperglycemia 3 endocrinologydiseases
hyperinsulinemia 4 endocrinologydiseases
obesity 4 endocrinologydiseases
type 2 diabetes mellitus 1 endocrinologydiseases
Insulin 1 endocrinologydiseasesdrugs

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Select Drug Character Offset Drug Term Instance
Insulin 10784 myocardial overload mediated by hyperinsulinemia and secondary activation of the sympathetic nervous system. Insulin increases cell growth, thus it has been suggested that cardiac hypertrophy in type 2 diabetes may result
Select Disease Character Offset Disease Term Instance
diabetes mellitus 500 (C.B.)Publication date (epub): 12/2016Publication date (collection): 12/2016AbstractIn recent years, type 2 diabetes mellitus has evolved as a rapidly increasing epidemic that parallels the increased prevalence of obesity and
diabetes mellitus 842 major cause of death in diabetic subjects, diabetic cardiomyopathy (DC) summarizes adverse effects of diabetes mellitus on the heart that are independent of coronary artery disease (CAD) and hypertension. DC increases the
diabetes mellitus 1753 and preclinical literature on the existence of human DC in the context of the two different types of diabetes mellitus .1. IntroductionDiabetes mellitus has become a rapidly growing epidemic in recent decades. Diabetic complications
hyperglycemia 19639 db/db mice, ob/ob mice and Zucker diabetic fatty rats [[36],[38],[39],[40]]. Depending on the degree of hyperglycemia and diabetes, systolic dysfunction is also observed in these models using echocardiography or using
hyperglycemia 20345 pathologic alterations in cardiomyocytes are primarily triggered by systemic metabolic alterations such as hyperglycemia , hyper- and dyslipidemia, hyperinsulinemia and insulin resistance. Increased myocardial fatty acid uptake
hyperglycemia 24644 of type 1 diabetes. In this respect, it should be noted that systemic metabolic derangements such as hyperglycemia and dyslipidemia are similar in most models of type 1 and type 2 diabetes, thus pointing towards differences
hyperinsulinemia 10707 function may be attributable to an increase in peripheral resistance and myocardial overload mediated by hyperinsulinemia and secondary activation of the sympathetic nervous system. Insulin increases cell growth, thus it has
hyperinsulinemia 10902 cell growth, thus it has been suggested that cardiac hypertrophy in type 2 diabetes may result from hyperinsulinemia [[21]]. Some authors also argue that subclinical systolic dysfunction detectable by strain imaging may
hyperinsulinemia 20385 primarily triggered by systemic metabolic alterations such as hyperglycemia, hyper- and dyslipidemia, hyperinsulinemia and insulin resistance. Increased myocardial fatty acid uptake and generation of toxic lipid intermediates
hyperinsulinemia 24834 thus pointing towards differences in myocardial insulin action (insulin resistance with accompanying hyperinsulinemia versus insulin deficiency) as an underling factor that may explain phenotypic differences between the
obesity 606 diabetes mellitus has evolved as a rapidly increasing epidemic that parallels the increased prevalence of obesity and which markedly increases the risk of cardiovascular disease across the globe. While ischemic heart
obesity 4878 importantly, adjustment for race, level of education, cigarette smoking, alcohol consumption, hypertension, obesity , ACE inhibitors, beta-blockers, diabetes type and duration, and interim myocardial infarction attenuated
obesity 6494 positive relationship between type 2 diabetes and an increased left ventricular mass, independent of obesity , race/ethnicity, physical activity and, in addition, they found a weaker association with the use of
obesity 11075 systolic dysfunction detectable by strain imaging may also be observed in many other conditions, including obesity , hypertension, and even healthy aging, and thus may not be specific to diabetes.3. Diabetic Cardiomyopathy
type 2 diabetes mellitus 493 (C.B.)Publication date (epub): 12/2016Publication date (collection): 12/2016AbstractIn recent years, type 2 diabetes mellitus has evolved as a rapidly increasing epidemic that parallels the increased prevalence of obesity and

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