Comparisons of Fatty Acid Taste Detection Thresholds in People Who Are Lean vs. Overweight or Obese: A Systematic Review and Meta-Analysis.

Existing Reviews

Please note, new claims can take a short while to show up.

No claims yet.

Annotation Summary

Term Occurence Count Dictionary
obesity 13 endocrinologydiseases

There are not enough annotations found in this document to create the proximity graph.


Having read the paper, please pick a pair of statements from the paper to indicate that a drug and disease are related.

Select Drug Character Offset Drug Term Instance
Select Disease Character Offset Disease Term Instance
obesity 1187 determine if relationships exist between oral sensitivity to NEFA (measured as thresholds), food intake and obesity . Published findings suggest there is either no association or an inverse association. A systematic review
obesity 2064 observed. Thus, differences in fatty acid taste sensitivity do not appear to precede or result from obesity .Data AvailabilityAll relevant data are within the paper and its Supporting Information files.IntroductionFlavor
obesity 3414 especially energy dense, special attention has been given to their role in promoting weight gain and obesity , but evidence is mixed [[21],[22]]. Although the majority of fat in the diet is in the form of esterified
obesity 5287 versus less sensitive but would not explain a level of intake that exceeds energy needs in those with obesity . Alternatively, it has been suggested that a high-fat diet leads to habituation and the need for an
obesity 25351 NEFA could contribute to differential fat intake, body weight and fat mass, or alternatively, does obesity alter taste responses for NEFA?Several mechanisms linking taste sensitivity to NEFA and adiposity have
obesity 25787 fatty acids by multiple mechanisms [[43]]. Lower salivary flow rates have been observed in people with obesity [[44]–[46]] and it may be posited that this would diminish taste responses. However, other evidence
obesity 25962 responses. However, other evidence indicates no difference in flow rates in people with and without obesity [[47],[48]]. Both acute [[17]] and habitual [[14]] fat intake reportedly downregulate expression of
obesity 26248 very preliminary data and, to be relevant, requires the unsubstantiated assumption that people with obesity necessarily select higher fat diets [[21],[49]]. Indeed, work reporting associations between fat intake
obesity 26578 assessments [[14]]. Finally, even if sensitivity or intensity ratings differed in people with or without obesity , this would not necessarily translate into altered fat taste preferences, intake or body adiposity as
obesity 26852 consumption. Taken together, there are hypotheses but no compelling mechanistic evidence that people with obesity should or do differ in fat taste sensitivity or responsiveness from their lean counterparts. This is
obesity 27255 observation that published studies only report no difference or diminished oleogustus in people with obesity warrants consideration. There are no reports of heightened sensitivity or intensity ratings by this
obesity 27585 account for this, but several testable hypotheses may be proposed. It is possible that people with obesity simply do not perform as well on the types of sensory tests that have been used to measure oleogustus
obesity 28076 Additionally, there may be confounding factors that contribute to lower observed sensitivity in people with obesity such as higher medication use and/or associated health disorders that alter taste function that were

You must be authorized to submit a review.