Description of a New Predictive Modeling Approach That Correlates the Risk and Associated Cost of Well-Defined Diabetes-Related Complications With Changes in Glycated Hemoglobin (HbA1c).

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Annotation Summary

Term Occurence Count Dictionary
Insulin 1 endocrinologydiseasesdrugs
diabetic ketoacidosis 1 endocrinologydiseases
hypoglycemia 3 endocrinologydiseases

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
Insulin 7162 Specifically, eligible reports included type 1 diabetes (T1DM) or type 2 diabetes (T2DM) populations. Insulin treatment was mandatory for search 1 and search 2 but not for search 3 (costs). A single failed eligibility
Select Disease Character Offset Disease Term Instance
diabetic ketoacidosis 11305 complications: angina, coronary heart failure (CHF)Myocardial infarction (MI)Brain complications: stroke, diabetic ketoacidosis (DKA)Eye diseases: proliferative retinopathy (PR), severe vision loss (blindness)Peripheral complications:
hypoglycemia 8558 common complications. Relationship results concerning nephropathy, retinopathy, cardiovascular diseases, hypoglycemia , and neuropathy were found in 47, 22, 15, 14, and 10 publications. The other complications were found
hypoglycemia 9227 eligible publications provided results with regard to incidences of the most common complications: hypoglycemia (n = 105), nephropathy (n = 64), cardiovascular diseases (n = 61), and retinopathy (n = 49). (D) The
hypoglycemia 9943 concerning nephropathy revealed 18 publications while 16 publications have cost results attributed to hypoglycemia . Hospitalization costs for diabetes management were found in 18 publications. The other complications

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