Effects of hyperandrogenism on metabolic abnormalities in patients with polycystic ovary syndrome: a meta-analysis

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hyperandrogenism 4 endocrinologydiseases
metabolic syndrome 7 endocrinologydiseases
obesity 3 endocrinologydiseases
polycystic ovary syndrome 3 endocrinologydiseases

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hyperandrogenism 63 Title: Reproductive Biology and Endocrinology : RB&EEffects of hyperandrogenism on metabolic abnormalities in patients with polycystic ovary syndrome: a meta-analysisRui YangShuo YangRong
hyperandrogenism 376 (pmc-release): 10/2016Publication date (collection): /2016AbstractBackgroundThe study evaluated the effect of hyperandrogenism (HA) in polycystic ovary syndrome (PCOS) on metabolic parameters.MethodsWe searched PubMed, EMBASE,
hyperandrogenism 2906 abnormalities [[2], [3]] in PCOS patients. As one of the most important clinical features of PCOS, hyperandrogenism (HA) tends to cause IR, where the free androgen level is generally higher and the IR extent is also
hyperandrogenism 4535 literature recall were supplemented. Keywords for the search included “polycystic ovary syndrome,” “ hyperandrogenism ,” “metabolic diseases,” and “metabolic syndrome,” etc.Inclusion and exclusion criteriaInclusion
metabolic syndrome 764 study evaluated PCOS patients with or without HA on metabolic parameters was included. Prevalence of metabolic syndrome , indexes of insulin resistance (IR) including homeostasis model assessment IR index (HOMA-IR), incidence
metabolic syndrome 1291 were having HA, and the others were negative. There were significant differences in the incidence of metabolic syndrome , HOMA-IR, rate of IR, TC level and HDL level between PCOS patients with or without HA, except for LDL
metabolic syndrome 1594 0.82.ConclusionsHA play an important role in metabolic disorders in PCOS patients. The incidence of metabolic syndrome , IR indexes, and most biomarkers of serum lipid metabolism were significantly different between patients
metabolic syndrome 2760 revealed different degrees of obesity, dyslipidemia, insulin resistance (IR), abnormal glucose metabolism, metabolic syndrome (MetS), and other metabolic abnormalities [[2], [3]] in PCOS patients. As one of the most important
metabolic syndrome 4589 included “polycystic ovary syndrome,” “hyperandrogenism,” “metabolic diseases,” and “ metabolic syndrome ,” etc.Inclusion and exclusion criteriaInclusion criteria: (1) Observation studies including cohort
metabolic syndrome 15901 response rate of the patients and the integrity of data collectionMeta-analysis resultsIncidence of metabolic syndrome Among the enrolled articles, the incidence of MetS was involved in 14 studies [a total of 5968 PCOS patients,
metabolic syndrome 21036 (Fig. 5).Fig. 5Funnel Plot analysis of publication bias of impact of hyperandrogenemia on the incidence of metabolic syndrome in PCOS patientsDiscussionsA total of 32 articles were included in this systematic assessment, and the
obesity 2200 manifests as oligomenorrhea/amenorrhea (O), oligoovulation/anovulation (O), and acne, etc., as well as obesity , hirsutism, and polycystic ovary (PCO), etc. Since 1990s, three diagnostic criteria have appeared for
obesity 2683 criteria developed by Androgen Excess Society (AES) in 2006. Studies revealed different degrees of obesity , dyslipidemia, insulin resistance (IR), abnormal glucose metabolism, metabolic syndrome (MetS), and
obesity 3072 level is generally higher and the IR extent is also significantly aggravated in females with central obesity compared with normal control group. Different possible mechanisms were reported in various studies,
polycystic ovary syndrome 124 Biology and Endocrinology : RB&EEffects of hyperandrogenism on metabolic abnormalities in patients with polycystic ovary syndrome : a meta-analysisRui YangShuo YangRong LiPing LiuJie QiaoYanwu ZhangPublication date (epub): 10/2016Publication
polycystic ovary syndrome 401 date (collection): /2016AbstractBackgroundThe study evaluated the effect of hyperandrogenism (HA) in polycystic ovary syndrome (PCOS) on metabolic parameters.MethodsWe searched PubMed, EMBASE, Cochrane, Web of Science, Chinese
polycystic ovary syndrome 4502 journals, and manual search or literature recall were supplemented. Keywords for the search included “ polycystic ovary syndrome ,” “hyperandrogenism,” “metabolic diseases,” and “metabolic syndrome,” etc.Inclusion and

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