Sugars, obesity, and cardiovascular disease: results from recent randomized control trials.

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Term Occurence Count Dictionary
obesity 23 endocrinologydiseases
Insulin 1 endocrinologydiseasesdrugs
metabolic syndrome 2 endocrinologydiseases

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
Insulin 23332 in a control diet have not shown adverse effects of multiple risk factors for diabetes [[82]–[86]]. Insulin resistance is an established risk factor with diabetes often preceding T2D by 10–20 years [[87]].
Select Disease Character Offset Disease Term Instance
metabolic syndrome 519 sugar consumption is associated with increased risk of obesity, coronary heart disease, diabetes (T2D), metabolic syndrome , non-alcoholic fatty liver disease, and stimulation of reward pathways in the brain potentially causing
metabolic syndrome 12894 overconsumption of calories leading to obesity and associated metabolic diseases including CVD, T2D, and metabolic syndrome (MetS).Multiple subsequent studies from research laboratories have not demonstrated any unique properties
obesity 44 Title: European Journal of NutritionSugars, obesity , and cardiovascular disease: results from recent randomized control trialsJames M. RippeTheodore J.
obesity 470 Some investigators have argued that excessive sugar consumption is associated with increased risk of obesity , coronary heart disease, diabetes (T2D), metabolic syndrome, non-alcoholic fatty liver disease, and
obesity 1766 relationship of sugar consumption and a range of health-related issues including energy-regulating hormones, obesity , cardiovascular disease, diabetes, and accumulation of liver fat and neurologic responses. Data from
obesity 2082 various adverse metabolic and health-related effects.The world is in the midst of twin epidemics of obesity and diabetes often lumped together as diabesity (T2D) [[1]–[6]]. It has been estimated that there
obesity 2546 million individuals, are obese, while an additional 74 million are overweight [[7]]. The prevalence of obesity grew a shocking 40 % over the last 30 years [[8]]. The obesity epidemic is truly global. In European
obesity 2611 overweight [[7]]. The prevalence of obesity grew a shocking 40 % over the last 30 years [[8]]. The obesity epidemic is truly global. In European countries, obesity ranges from 20 to 30 % and is even higher
obesity 2668 shocking 40 % over the last 30 years [[8]]. The obesity epidemic is truly global. In European countries, obesity ranges from 20 to 30 % and is even higher in Australia, South America, Middle-East, and Polynesia [[1]].The
obesity 3861 epidemiologic studies have linked consumption of added sugars to increased risk of weight gain and obesity [[14]–[16]], increased risk factors for cardiovascular disease (CVD) [[17]] including hypertension
obesity 9673 energy-regulating hormones could create an environment resulting in increased hunger, food consumption, and obesity when consuming fructose [[38], [39]].The differences between fructose and glucose effects on energy-regulating
obesity 11919 metabolic differences between fructose and glucose can lead to an environment that promotes weight gain and obesity must be treated with extreme caution particularly when these two monosaccharides are evaluated at levels
obesity 12199 contrast to how they are normally consumed in the human diet which is invariably together.Sugars and obesity The modern concern about a potential role of sugars as a unique cause for obesity seems to have originated
obesity 12280 together.Sugars and obesityThe modern concern about a potential role of sugars as a unique cause for obesity seems to have originated with a review article published in the American Journal of Clinical Nutrition
obesity 12578 question of whether there was a unique relationship between HFCS consumption and the rapid increase in the obesity epidemic in the USA. These researchers noted a temporal relationship between increasing consumption
obesity 12698 the USA. These researchers noted a temporal relationship between increasing consumption of HFCS and obesity and argued that the metabolism of fructose could result in increased likelihood of overconsumption of
obesity 12828 metabolism of fructose could result in increased likelihood of overconsumption of calories leading to obesity and associated metabolic diseases including CVD, T2D, and metabolic syndrome (MetS).Multiple subsequent
obesity 13408 concluding that there are no differences between HFCS and sucrose with regard to the likelihood of causing obesity .The literature related to sugars and obesity has subsequently shifted to a consideration of whether
obesity 13453 HFCS and sucrose with regard to the likelihood of causing obesity.The literature related to sugars and obesity has subsequently shifted to a consideration of whether any fructose containing sugars such as sucrose,
obesity 13617 any fructose containing sugars such as sucrose, HFCS, or concentrated fruit juices may contribute to obesity . Several meta-analyses have suggested that sugar sweetened soft drinks (SSBs) are associated with weight
obesity 13739 meta-analyses have suggested that sugar sweetened soft drinks (SSBs) are associated with weight gain and obesity in both children and adults [[14], [15]]. There have been three recent systematic reviews and meta-analyses
obesity 16119 Thus, data related to added sugar intake as a potential significant contributor to weight gain and obesity must be treated with great caution. Moreover, public policy attempts to limit sugar consumption as a
obesity 21823 10 % decrease in the contribution of sugar in beverages has recently occurred despite increases in obesity and diabetes [[74]]. This has been labeled the “Australian Paradox.” Similar “paradoxes” have
obesity 22058 [[75]] and Canada where a 15 % sugar consumption decline has occurred over the past decade, while both obesity and diabetes have increased.Prospective cohort studies provide mixed evidence concerning sugar consumption
obesity 30027 with decreased physical activity in increasing the risk of interrelated metabolic diseases such as obesity , CHD, T2D, and NAFLD

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