Therapeutic Effects of Quercetin on Inflammation, Obesity, and Type 2 Diabetes

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obesity 11 endocrinologydiseases
metabolic syndrome 1 endocrinologydiseases

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metabolic syndrome 1679 due to a growth in obesity, especially excess visceral adiposity, in addition to the associated “ metabolic syndrome ” which encompasses insulin resistance, hyperglycaemia, dyslipidaemia, and hypertension [[1]].Inflammation
obesity 642 ChinaPublication date (ppub): /2016Publication date (epub): 11/2016AbstractIn previous studies, abdominal obesity has been related to total low-grade inflammation and in some cases has resulted in insulin resistance
obesity 1364 beneficial effects. This manuscript reviewed quercetin's anti-inflammatory properties in relation to obesity and type 2 diabetes.1. IntroductionThe world has seen a rapid increase in the incidence of diabetes
obesity 1599 diabetes has become the most common metabolic disease globally. This has been in part due to a growth in obesity , especially excess visceral adiposity, in addition to the associated “metabolic syndrome” which
obesity 1986 chronic inflammation and the activation of the immune system may be mainly responsible for the process of obesity -related metabolic diseases such as type 2 diabetes [[2], [3]]. Key characteristics of type 2 diabetes
obesity 3755 resistance, diabetes, and a higher possibility of contracting cardiovascular disease has been linked to obesity [[8]]. Examinations of overweight and obese adults have revealed altered circulating levels of inflammatory
obesity 4113 Although body fat generally has been correlated with serum levels of inflammatory proteins, abdominal obesity has shown a stronger correlation than either Body Mass Index (BMI) or total body fat [[9]], for all
obesity 5060 TNF-α, IL-6, and IL-1β [[10], [12]]. Additionally, irrespective of the level of insulin resistance and obesity at the outset, an independent risk factor for the development of type 2 diabetes seems to be subclinical
obesity 11609 disease. It could also potentially prove useful to cells involved in allergic inflammation [[38]].6. Anti obesity Effect of QuercetinResearch suggested that quercetin downregulated adipogenesis and apoptosis by decreasing
obesity 12399 expression and lipid metabolism [[40]]. Studies showed that quercetin prevents high-fat diet (HFD) induced obesity in C57B1/6 mice, perhaps by regulating lipogenesis. Mice fed a quercetin supplement saw a significant
obesity 12533 by regulating lipogenesis. Mice fed a quercetin supplement saw a significant lowering of HFD induced obesity compared to those fed the HFD without the supplement. Specifically, the supplement-fed mice experienced
obesity 15242 quality-of-life matrices [[45]].8. ConclusionsEvidence in various studies seems to connect abdominal obesity , type 2 diabetes, and chronic low-grade inflammation. Researchers have begun to view type 2 diabetes

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