25-Hydroxyvitamin D Status and Risk for Colorectal Cancer and Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis of Epidemiological Studies.

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Term Occurence Count Dictionary
hyperglycemia 2 endocrinologydiseases
hyperlipidemia 1 endocrinologydiseases
metabolic syndrome 1 endocrinologydiseases
obesity 1 endocrinologydiseases
type 2 diabetes mellitus 4 endocrinologydiseases
diabetes mellitus 7 endocrinologydiseases
glucose intolerance 1 endocrinologydiseases

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diabetes mellitus 748 vitamin D status and risk for various outcomes including cardiovascular diseases, cancer, and type 2 diabetes mellitus (T2DM). Analyzing serum 25-hydroxyvitamin D [25(OH)D] is the most established means to evaluate an individual’s
diabetes mellitus 7086 performed on 31 August 2016 using the terms (vitamin D or 25(OH)D or 25-hydroxyvitamin D) and (diabetes or diabetes mellitus ) with studies published after 1 January 2012.Each publication, whether previously included in a meta-analysis
diabetes mellitus 18268 cross-sectional study in community-dwelling men aged 70 and older it was shown that poor health, self-reported diabetes mellitus and hyperglycemia, depression, muscle weakness and poor balance, and also all-cause mortality were associated
diabetes mellitus 28270 (I–V) and random-effects (D–L) meta-analysis regarding the effects of 25(OH)D status on type 2 diabetes mellitus risk in case-control and cohort studies. Participants with 25(OH)D concentrations between approximately
diabetes mellitus 28712 (I–V) and random-effects (D–L) meta-analysis regarding the effects of 25(OH)D status on type 2 diabetes mellitus risk in case-control and cohort studies. Participants with the highest 25(OH)D concentrations were compared
diabetes mellitus 29086 shown.Figure 6Dose–response relationship between 25(OH)D concentrations and the relative risk for type 2 diabetes mellitus . Results of restricted cubic splines analysis of relative risks standardized to a common reference category
diabetes mellitus 36483 2.496.ijerph-14-00127-t002_Table 2Table 2Summary of observational studies for 25(OH)D status and risk for (type 2) diabetes mellitus included in the systematic review.ReferenceStudy DesignPopulationCountryParticipantsCategoriesOR/HRng/mL
glucose intolerance 18067 correlate with insulin resistance, obesity, aberrant phasing of insulin responses to glucose loading, glucose intolerance , fasting hyperglycemia, or also T2DM [[106],[107],[108]]. In a recent cross-sectional study in community-dwelling
hyperglycemia 18096 resistance, obesity, aberrant phasing of insulin responses to glucose loading, glucose intolerance, fasting hyperglycemia , or also T2DM [[106],[107],[108]]. In a recent cross-sectional study in community-dwelling men aged
hyperglycemia 18290 community-dwelling men aged 70 and older it was shown that poor health, self-reported diabetes mellitus and hyperglycemia , depression, muscle weakness and poor balance, and also all-cause mortality were associated with serum
hyperlipidemia 4207 low 25(OH)D levels have also been associated with development of T2DM [[13]], hypertension [[14]], hyperlipidemia [[15]], and cardiovascular diseases [[16]]. Therefore, in addition to relating the 25(OH)D status to
metabolic syndrome 20907 example, non-vertebral fractures, cardiovascular disease, hypertension, stroke, depression, prevalence of metabolic syndrome , T2DM, and colorectal cancer [[97]].Regarding the latter outcome, our results are in line with six previous
obesity 18000 [[105]].In addition to mortality, reduced serum 25(OH)D was shown to correlate with insulin resistance, obesity , aberrant phasing of insulin responses to glucose loading, glucose intolerance, fasting hyperglycemia,
type 2 diabetes mellitus 741 between low vitamin D status and risk for various outcomes including cardiovascular diseases, cancer, and type 2 diabetes mellitus (T2DM). Analyzing serum 25-hydroxyvitamin D [25(OH)D] is the most established means to evaluate an individual’s
type 2 diabetes mellitus 28263 the fixed (I–V) and random-effects (D–L) meta-analysis regarding the effects of 25(OH)D status on type 2 diabetes mellitus risk in case-control and cohort studies. Participants with 25(OH)D concentrations between approximately
type 2 diabetes mellitus 28705 the fixed (I–V) and random-effects (D–L) meta-analysis regarding the effects of 25(OH)D status on type 2 diabetes mellitus risk in case-control and cohort studies. Participants with the highest 25(OH)D concentrations were compared
type 2 diabetes mellitus 29079 shown.Figure 6Dose–response relationship between 25(OH)D concentrations and the relative risk for type 2 diabetes mellitus . Results of restricted cubic splines analysis of relative risks standardized to a common reference category

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