Prevalence of vascular complications and factors predictive of their development in young adults with type 1 diabetes: systematic literature review.

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aneurysm 1 angiologydiseases
thrombosis 1 angiologydiseases
vascular disease 11 angiologydiseases

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aneurysm 7488 characteristic evolution of typical retinal microvascular lesions in an individual with diabetes. Besides micro- aneurysm s, blood vessel changes include intra-retinal haemorrhage, and vascular tortuosity and malformation (non-proliferative
thrombosis 3657 platelet activation and fibrinolysis [[7]]. In combination with population-wide cardiovascular and athero- thrombosis risk factors, a state of persistent and progressive damage to the vascular wall (macro-angiopathy) is
vascular disease 1674 decreased to approximately one in ten participants. Glycaemic control was a consistent predictor of vascular disease in this age group.ConclusionPrevalence rates of retinopathy, nephropathy and hypertension in young adults
vascular disease 3354 appropriate information and support with the aim of deferring or averting their onset.The development of vascular disease in type 1 diabetes has been proposed as a consequence of disordered activity of lipid metabolism enzymes
vascular disease 4160 transplantation. This is in addition to hypertension, which is linked to peripheral, cardio- and cerebro vascular disease , the end points of which are limb amputations, cardiac failure, stroke and sudden death. As vascular
vascular disease 26110 diabetes duration and control (increasing HbA1c), and with prevalence and severity of other forms of vascular disease and population-wide markers of vascular risk such as triglyceride levels and weight [[51]–[55]].The
vascular disease 27268 predisposes to stroke, myocardial infarction, cardiac failure and limb amputation as well as other vascular disease manifestations such as retinopathy and nephropathy. A trend seen in slightly older young adults with
vascular disease 27444 seen in slightly older young adults with type 1 diabetes was of any one end-organ manifestation of vascular disease indicating an increased likelihood of concurrent vascular disease in other areas. For example, in cohorts
vascular disease 27510 any one end-organ manifestation of vascular disease indicating an increased likelihood of concurrent vascular disease in other areas. For example, in cohorts with mild/severe renal failure, 71.4% and 83.3%, respectively,
vascular disease 28320 80% adherence rates in routine care and this is especially important for this patient group as cardio vascular disease occurs more than ten times more frequently in those with type 1 diabetes than in age-matched non-diabetes
vascular disease 28891 scarce and this quantitative epidemiological systematic review found glycaemic control as predictive of vascular disease in young adults with type 1 diabetes. Diabetes duration was also flagged, of concern because it is not
vascular disease 29255 years with type 1 diabetes almost half of young adults had retinal damage [[36]] - and probably other vascular disease as well.On the other hand glycaemic control is modifiable and influential. The deterioration that accrues
vascular disease 32407 nephropathy and hypertension in young adults with type 1 diabetes. While data were limited, underlying vascular disease manifesting as retinopathy and hypertension was common amongst this group, with development predicted

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