Modified low density lipoprotein and lipoprotein-containing circulating immune complexes as diagnostic and prognostic biomarkers of atherosclerosis and type 1 diabetes macrovascular disease.

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thrombosis 1 angiologydiseases
vascular disease 7 angiologydiseases

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thrombosis 19933 endothelial cells, vascular smooth muscle cells (VSMCs), and monocytes, and enhance vasoconstriction, thrombosis , and platelet aggregation. Furthermore, in atherosclerotic vessels, increased LDL levels stimulate endothelial
vascular disease 2290 Accumulating evidence indicates that LDL-containing immune complexes can also serve as biomarker for macro vascular disease in type 1 diabetes.1. IntroductionAtherosclerosis results in the inner layer of the arterial wall and
vascular disease 3202 obtained data about a relation of apolipoproteins to risk scores led to slight improvement in cardio vascular disease risk prediction [[10]].It is well known that atherosclerosis develops asymptomatically affecting the
vascular disease 4130 immune complexes which emerge to be diagnostic and prognostic biomarker of atherosclerosis and macro vascular disease in type 1 diabetes.2. Low Density LipoproteinLipid deposition in the arterial wall is widely recognized
vascular disease 14023 trimethylamine N-oxide (TMAO), and betaine, e.g., to catabolites that increase risk of atherosclerosis and cardio vascular disease [[55]].Sphingomyelin is an essential structural component of serum lipoproteins and the second major
vascular disease 18757 apoB and apoA-I, lipoprotein (a), or lipoprotein-associated phospholipase A2 does not improve cardio vascular disease (CVD) prediction but adding these markers to the combination of total cholesterol and HDL cholesterol
vascular disease 25792 by a specific monoclonal antibody for atherosclerosis-related events including coronary and cerebral vascular disease . In a follow-up study of 326 clinically healthy Swedish men, Wallenfeldt et al. [[105]] showed association
vascular disease 61081 complexes may provide a physiological link and explain whereby elevated LDL levels contribute to macro vascular disease in type 1 diabetes. Similar experiments should be performed in atherosclerotic patients and type 2 diabetic

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