Systemic Activation of Activin A Signaling Causes Chronic Kidney Disease-Mineral Bone Disorder

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chronic kidney disease 1 nephrologydiseases
renal osteodystrophy 1 nephrologydiseases

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chronic kidney disease 462 8/2018Publication date (collection): 9/2018AbstractThe high cardiovascular mortality associated with chronic kidney disease (CKD) is caused in part by the CKD-mineral bone disorder (CKD-MBD) syndrome. The CKD-MBD consists of
renal osteodystrophy 784 disease. The prevalence of osteopenia/osteoporosis resulting from the skeletal component of the CKD-MBD, renal osteodystrophy (ROD), in patients with CKD exceeds that of the general population and is a major public health concern.

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