Year in review 2013: Critical Care - nephrology

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Annotation Summary

Term Occurence Count Dictionary
furosemide 1 nephrologydiseasesdrugs
metabolic acidosis 1 nephrologydiseases
acute kidney injury 4 nephrologydiseases
chronic kidney disease 5 nephrologydiseases

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Select Drug Character Offset Drug Term Instance
furosemide 13326 progression of AKI. These authors also found that chronic kidney disease, higher lactate, higher dose of furosemide , use of dobutamine and time-adjusted MAP below 73 mmHg were independent predictors of progression of
Select Disease Character Offset Disease Term Instance
acute kidney injury 451 studies, in other journals. Three main topics have been identified and are discussed for a rapid overview: acute kidney injury (diagnosis, risk factors and outcome); timing and modality of renal replacement therapy; and extracorporeal
acute kidney injury 2606 AKI criteria (Table 1).Table 1Kidney disease: improving global outcome (KDIGO) classification for acute kidney injury diagnosisStage 1Stage 2Stage 3KDIGO (2012)↑sCr ≥0.3 mg/dl (26.5 μmol/l) within 48 hours↑sCr
acute kidney injury 3265 filtration rate; RRT, renal replacement therapy; sCr, serum creatinine; UO, urine output.Diagnosis of acute kidney injury Apart from the specific issue of AKI classification, accurate assessment of kidney function in the critically
acute kidney injury 9137 examinations and clinical signs, remain the mainstay of AKI diagnosis.Risk factors and hemodynamics of acute kidney injury Kellum and Lameire [[1]] proposed the concept of risk factors and susceptibility. The main external stressors
chronic kidney disease 8285 Health Evaluation III score, hypertension, nephrotoxic drugs, liver disease, sepsis, diabetes, and chronic kidney disease . After definitive clinical validation, the application of novel AKI biomarkers will permit appropriate
chronic kidney disease 9711 susceptibility factors we may consider advanced age, dehydration or volume depletion, female gender, black race, chronic kidney disease , diabetes mellitus, cancer and anemia. Therefore, it is important to screen patients who have undergone
chronic kidney disease 13271 73 mmHg for time-adjusted MAP best predicted the progression of AKI. These authors also found that chronic kidney disease , higher lactate, higher dose of furosemide, use of dobutamine and time-adjusted MAP below 73 mmHg were
chronic kidney disease 20428 considered early starters. AKIN criteria were evaluated by both urine output and sCr. Patients with acute-on- chronic kidney disease were excluded from this study. A total of 358 critically ill patients were managed with RRT but only
chronic kidney disease 25557 accurate according to pediatric RIFLE classification. Since AKI during childhood may predispose to chronic kidney disease in adulthood, we believe that long-term monitoring of kidney function after neonatal ECMO should be
metabolic acidosis 19261 sCr (300 μmol/l) or urea (40 mmol/l) were similar, there was a higher priority with hyperkalemia, metabolic acidosis and volume overload. In addition, they demonstrated a trend towards early initiation of RRT, with the

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