Signalling pathways involved in hypoxia-induced renal fibrosis.

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chronic kidney disease 1 nephrologydiseases
kidney failure 1 nephrologydiseases

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chronic kidney disease 725 date (ppub): 7/2017AbstractAbstractRenal fibrosis is the common pathological hallmark of progressive chronic kidney disease (CKD) with diverse aetiologies. Recent researches have highlighted the critical role of hypoxia during
kidney failure 28853 participated in the hypoxia‚Äźinduced EMT and renal fibrosis and its overexpression was correlated with kidney failure prognosis. Chronic hypoxia stimulated URG11 expression in UUO model, which, in turn, suppressed the

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