An Integrated View of Aristolochic Acid Nephropathy: Update of the Literature

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Term Occurence Count Dictionary
Fanconi syndrome 2 nephrologydiseases
acute kidney injury 1 nephrologydiseases
chronic kidney disease 1 nephrologydiseases
interstitial nephritis 3 nephrologydiseases
kidney failure 1 nephrologydiseases

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Fanconi syndrome 6955 Kingdom in patients treated with Chinese herb remedies for eczema [[24]]. In Germany, a case a reversible Fanconi syndrome in a patient treated for hyper-uricaemia was observed [[25]]. AAN cases have also been described outside
Fanconi syndrome 13505 not suspected and was discovered by routine blood testing [[15]]. Besides few cases presenting with a Fanconi syndrome [[25],[34],[39],[63]], most cases were characterized by renal failure. However, a hallmark of the disease
acute kidney injury 32652 thereafter remaining at a stable level up to the end of the protocol (Day 35). This early phase of acute kidney injury (AKI), also described in mice models [[75],[110]], was rapidly followed by infiltration of inflammatory
chronic kidney disease 54168 events could contribute to tubular injury and to further progression to fibrogenesis characterizing chronic kidney disease .Figure 6Involvement of TGF-β/Smad pathway in AA-induced fibrogenesis. TGF-β is overexpressed in AAN
interstitial nephritis 2384 often not considered in AAN.1. IntroductionIn the early 1990s, an epidemic of rapidly progressive tubulo interstitial nephritis was reported in Belgium in a cohort of young female patients. The onset of this the renal disease was
interstitial nephritis 6300 1998 and 70% of these patients developed ESRD [[1],[7],[15],[21]]. Furthermore, other cases of severe interstitial nephritis associated with progressive renal failure and urothelial malignancies consequently to the intake of
interstitial nephritis 33877 the biphasic evolution described experimentally by Lebeau et al. Biopsies of these patients revealed interstitial nephritis , interstitial inflammatory infiltrate and evidence of acute tubular necrosis [[29],[31],[113]]. As experimentally
kidney failure 33478 (CKD) [[109]].Most of AAN cases that are reported in the literature describe patients with chronic kidney failure characterized by a typical interstitial fibrosis. Symptoms associated to AA nephrotoxicity can be detected

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