Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review.

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Term Occurence Count Dictionary
arthritis 9 rheumatologydiseases
myopathy 1 rheumatologydiseases
osteoarthritis 2 rheumatologydiseases
rheumatoid arthritis 2 rheumatologydiseases

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arthritis 1782 synoviocytes, along with immunomodulation properties on T and B lymphocytes. In preclinical models of osteo arthritis and rheumatoid arthritis, resveratrol has shown joint protective effects, mainly mediated by decreased
arthritis 1807 immunomodulation properties on T and B lymphocytes. In preclinical models of osteoarthritis and rheumatoid arthritis , resveratrol has shown joint protective effects, mainly mediated by decreased production of pro-inflammatory
arthritis 15265 that active metabolites of t-Res might have beneficial effects in preventing and treating rheumatoid arthritis (RA). Finally, resveratrol inhibits cell adhesion between monocytes and endothelial cells [[61]], a
arthritis 16166 platelet aggregation [[3]]. Only few papers have specifically investigated effects of t-Res in osteo arthritis (OA) or RA animal models.In most of the studies in OA animal models, t-Res was administered by intra-articular
arthritis 18456 such as resveratrol in this effect. t-Res alleviated cartilage destruction and inflammation in murine arthritis induced by collagen or lipopolysaccharides [[69],[70],[71],[72]]. From a mechanistic point of view,
arthritis 18631 From a mechanistic point of view, Xuzhu and colleagues demonstrated, in the mouse collagen-induced arthritis model, that either prophylactic or therapeutic administration of resveratrol attenuated clinical arthritis
arthritis 18738 arthritis model, that either prophylactic or therapeutic administration of resveratrol attenuated clinical arthritis parameters and bone erosions, and was associated with reduced serum levels of pro-inflammatory cytokines
arthritis 19162 key cellular and humoral responses [[72]]. Most recently, Chen and colleagues, in the rat adjuvant arthritis model, reported that resveratrol (10 or 50 mg/kg) significantly reduced paw swelling and arthritis scores,
arthritis 19261 arthritis model, reported that resveratrol (10 or 50 mg/kg) significantly reduced paw swelling and arthritis scores, with suppression of synovial hyperplasia and inflammatory cell infiltrate, and reduction in
myopathy 7672 t-Res and Sirt-1 activation leading to cardiac function improvement in animal models of diabetic cardio myopathy has been suggested [[30]]. However, whether these findings can be translated to other cardiovascular
osteoarthritis 1777 synoviocytes, along with immunomodulation properties on T and B lymphocytes. In preclinical models of osteoarthritis and rheumatoid arthritis, resveratrol has shown joint protective effects, mainly mediated by decreased
osteoarthritis 16161 about platelet aggregation [[3]]. Only few papers have specifically investigated effects of t-Res in osteoarthritis (OA) or RA animal models.In most of the studies in OA animal models, t-Res was administered by intra-articular
rheumatoid arthritis 1796 with immunomodulation properties on T and B lymphocytes. In preclinical models of osteoarthritis and rheumatoid arthritis , resveratrol has shown joint protective effects, mainly mediated by decreased production of pro-inflammatory
rheumatoid arthritis 15254 concluded that active metabolites of t-Res might have beneficial effects in preventing and treating rheumatoid arthritis (RA). Finally, resveratrol inhibits cell adhesion between monocytes and endothelial cells [[61]], a

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