Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus.

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autoimmune disease 1 rheumatologydiseases
systemic lupus erythematosus 1 rheumatologydiseases

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autoimmune disease 1384 signaling pathways are highlighted.1. IntroductionSystemic lupus erythematosus (SLE) is a systemic autoimmune disease characterized by accumulation of anti-nuclear autoantibodies, hyperactivation of immune cells and multiple
systemic lupus erythematosus 716 are a large family of pattern recognition receptors. TLR signals are involved in the pathogenesis of systemic lupus erythematosus . Mouse and human B cells constitutively express most TLRs. Many B cell subpopulations are highly responsive

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