Osteoarthritis and the Mediterranean Diet: A Systematic Review

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Term Occurence Count Dictionary
arthritis 23 rheumatologydiseases
osteoarthritis 13 rheumatologydiseases
rheumatoid arthritis 1 rheumatologydiseases
synovitis 1 rheumatologydiseases

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arthritis 21 Title: NutrientsOsteo arthritis and the Mediterranean Diet: A Systematic ReviewIsabel Morales-IvorraMontserrat Romera-BauresBlanca Roman-ViñasLluis
arthritis 997 08028 Barcelona, SpainPublication date (epub): 8/2018Publication date (collection): 8/2018AbstractOsteo arthritis (OA) affects 240 million people globally. Few studies have examined the links between osteoarthritis
arthritis 1098 8/2018AbstractOsteoarthritis (OA) affects 240 million people globally. Few studies have examined the links between osteo arthritis and the Mediterranean diet (MD). The aim of this paper was to systematically review and analyze the
arthritis 2228 conclusion, the three studies included in this systematic review demonstrated some relation between osteo arthritis and a Mediterranean diet. However, prospective and longer interventions are required to evaluate the
arthritis 2430 evaluate the long-term efficacy of the Mediterranean diet to improve symptomatology and preventing osteo arthritis .1. IntroductionDietary patterns in Mediterranean countries during the early 1960s have been linked to
arthritis 3227 moderate, intake of red wine and olive oil as the main source of dietary lipids [[7],[8],[9],[10]].Osteo arthritis (OA) affects 240 million people globally, about 10% of men and 18% of women [[11]]. Clinical manifestations
arthritis 3847 weight leads to wear and tear of the joint [[15]]. The association between overweight and hand osteo arthritis suggests that factors other than mechanical forces may play also a role [[16]]. Nowadays, it is accepted
arthritis 4901 [[22],[23]]. Moreover, some studies have demonstrated that nutrition can have a beneficial role in osteo arthritis [[24],[25],[26]]. Different groups have demonstrated a protector effect of the Mediterranean diet in
arthritis 5272 polyphenols which prevent inflammation and cartilage destruction, resulting in a prevention of osteo arthritis -related musculoskeletal inflammation [[30]]. MD also produces a lower n-6 to n-3 fatty acid (FA) ratio.
arthritis 5950 study was to systematically review and analyze epidemiological studies on the links between MD and osteo arthritis .2. Materials and MethodsAn EMBASE search was conducted up to December 2017 in order to identify epidemiological
arthritis 6147 identify epidemiological studies on MD and OA. The search strategy applied was as follows: (‘osteo arthritis ’/exp/mj OR ‘osteoarthritis’/major focus term (mj)) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean
arthritis 6178 studies on MD and OA. The search strategy applied was as follows: (‘osteoarthritis’/exp/mj OR ‘osteo arthritis ’/major focus term (mj)) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj). All
arthritis 7327 risk of bias for the trial was considered to be unclear.3. ResultsThe EMBASE search strategy (‘osteo arthritis ’/exp/mj OR ‘osteoarthritis’/mj) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj)
arthritis 7358 considered to be unclear.3. ResultsThe EMBASE search strategy (‘osteoarthritis’/exp/mj OR ‘osteo arthritis ’/mj) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj) yielded a total of eight
arthritis 7851 findings [[37],[38],[39]]. Two articles reported cross-sectional data from the same study, namely the Osteo arthritis Initiative conducted in the USA [[38],[39]], while the third was a randomized controlled trial [[37]].
arthritis 11072 disease-specific measure of the physical, social, and emotional well-being designed as a measure of outcome in arthritis . It encompasses nine scales: mobility, physical activity (walking, bending, lifting), dexterity, household
arthritis 12626 between MD and improved quality of life in participants with OA [[37],[38],[39]]. The prevalence of osteo arthritis was lower in participants with high aMED [[38]]. Biomarkers of inflammation and cartilage degradation
arthritis 13432 development and progression of OA [[43]]. Inflammation in OA joints is distinct from that in rheumatoid arthritis as it is chronic, low grade and mediated by innate immunity [[42]]. Different studies have shown that
arthritis 16629 review.nutrients-10-01030-t001_Table 1Table 1Epidemiological studies on mediterranean diet and osteo arthritis .Author, YearCountry Population, N (sex) AgeSample CharacteristicsMD Definition. Diets and Other InterventionsOsteoarthritisFollow-UpResultsDyer
arthritis 16753 YearCountry Population, N (sex) AgeSample CharacteristicsMD Definition. Diets and Other InterventionsOsteo arthritis Follow-UpResultsDyer J et al., 2017 [[37]].UKN = 99 (83% female)Age: 31–90 years.Volunteers with a
arthritis 17896 [[38]].USAN = 4358 (2527 females)Mean age: 61.2 ± 9.1 years.Community-dwelling participants from the Osteo arthritis Initiatives were includedThe Mediterranean diet score proposed by Panagiotakos et al. was used to evaluate
arthritis 18796 [[39]].USAN = 4470 (2605 females)Mean age: 61.3 ± 9.2 years.Community-dwelling participants from the Osteo arthritis .Initiatives were included.The Mediterranean diet score proposed by Panagiotakos et al. [[40]] was used
arthritis 19753 food frequency questionnaire; MCS: Mental composite scale of SF-12; MD: Mediterranean Diet; OA: Osteo arthritis ; PCS: Physical composite scale of SF-12; ROM: Range of motion; SF-12: 12-Item Short-Form Health Outcome
osteoarthritis 1093 8/2018AbstractOsteoarthritis (OA) affects 240 million people globally. Few studies have examined the links between osteoarthritis and the Mediterranean diet (MD). The aim of this paper was to systematically review and analyze the
osteoarthritis 2223 conclusion, the three studies included in this systematic review demonstrated some relation between osteoarthritis and a Mediterranean diet. However, prospective and longer interventions are required to evaluate the
osteoarthritis 2425 evaluate the long-term efficacy of the Mediterranean diet to improve symptomatology and preventing osteoarthritis .1. IntroductionDietary patterns in Mediterranean countries during the early 1960s have been linked to
osteoarthritis 3842 body weight leads to wear and tear of the joint [[15]]. The association between overweight and hand osteoarthritis suggests that factors other than mechanical forces may play also a role [[16]]. Nowadays, it is accepted
osteoarthritis 4896 [[22],[23]]. Moreover, some studies have demonstrated that nutrition can have a beneficial role in osteoarthritis [[24],[25],[26]]. Different groups have demonstrated a protector effect of the Mediterranean diet in
osteoarthritis 5267 rich in polyphenols which prevent inflammation and cartilage destruction, resulting in a prevention of osteoarthritis -related musculoskeletal inflammation [[30]]. MD also produces a lower n-6 to n-3 fatty acid (FA) ratio.
osteoarthritis 5945 study was to systematically review and analyze epidemiological studies on the links between MD and osteoarthritis .2. Materials and MethodsAn EMBASE search was conducted up to December 2017 in order to identify epidemiological
osteoarthritis 6142 order to identify epidemiological studies on MD and OA. The search strategy applied was as follows: (‘ osteoarthritis ’/exp/mj OR ‘osteoarthritis’/major focus term (mj)) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean
osteoarthritis 6173 studies on MD and OA. The search strategy applied was as follows: (‘osteoarthritis’/exp/mj OR ‘ osteoarthritis ’/major focus term (mj)) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj). All
osteoarthritis 7322 the risk of bias for the trial was considered to be unclear.3. ResultsThe EMBASE search strategy (‘ osteoarthritis ’/exp/mj OR ‘osteoarthritis’/mj) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj)
osteoarthritis 7353 was considered to be unclear.3. ResultsThe EMBASE search strategy (‘osteoarthritis’/exp/mj OR ‘ osteoarthritis ’/mj) AND (‘Mediterranean diet’/exp/mj OR ‘Mediterranean diet’/mj) yielded a total of eight
osteoarthritis 12621 between MD and improved quality of life in participants with OA [[37],[38],[39]]. The prevalence of osteoarthritis was lower in participants with high aMED [[38]]. Biomarkers of inflammation and cartilage degradation
osteoarthritis 16624 systematic review.nutrients-10-01030-t001_Table 1Table 1Epidemiological studies on mediterranean diet and osteoarthritis .Author, YearCountry Population, N (sex) AgeSample CharacteristicsMD Definition. Diets and Other InterventionsOsteoarthritisFollow-UpResultsDyer
rheumatoid arthritis 13421 of the development and progression of OA [[43]]. Inflammation in OA joints is distinct from that in rheumatoid arthritis as it is chronic, low grade and mediated by innate immunity [[42]]. Different studies have shown that
synovitis 13586 innate immunity [[42]]. Different studies have shown that the presence of synovial inflammation, or synovitis , in OA is associated with increased severity of joint symptoms, increased cartilage loss, decreased

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