Anti-citrullinated peptide/protein antibody (ACPA)-negative RA shares a large proportion of susceptibility loci with ACPA-positive RA: a meta-analysis of genome-wide association study in a Japanese population.

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arthritis 7 rheumatologydiseases
rheumatoid arthritis 5 rheumatologydiseases

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arthritis 937 /2015AbstractIntroductionAlthough susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by genome-wide association studies (GWAS), little is known about
arthritis 2959 (doi:10.1186/s13075-015-0623-4) contains supplementary material, which is available to authorized users.IntroductionRheumatoid arthritis (RA) is the most common autoimmune arthritis worldwide with prevalence of around 1%. Genetic factors
arthritis 3004 is available to authorized users.IntroductionRheumatoid arthritis (RA) is the most common autoimmune arthritis worldwide with prevalence of around 1%. Genetic factors as well as environmental factors are involved
arthritis 15502 genome-wide association studies (GWAS) for anti-citrullinated peptide/protein antibody-negative rheumatoid arthritis . The horizontal line indicates the GWAS significance level (P = 5 × 10−8).Next, we performed
arthritis 17431 0.90)0SNP, single nucleotide polymorphism; ACPA, anti-citrullinated peptide/protein antibody; RA, rheumatoid arthritis ; GWAS, genome-wide association studies; OR, odds ratio; Chr, chromosome; Ref, reference; Var, variance;
arthritis 18710 susceptibility loci with ACPA-positive RA (Figure 2B).Figure 2Correlation of odds ratios (ORs) of rheumatoid arthritis (RA) susceptibility single nucleotide polymorphisms (SNPs) for anti-citrullinated peptide/protein antibody
arthritis 21364 nucleotide polymorphisms (SNPs) among anti-citrullinated peptide/protein antibody (ACPA)-positive rheumatoid arthritis (RA) and the two subsets of ACPA-negative RA. Correlation coefficient of ORs between ACPA-positive RA
rheumatoid arthritis 926 /2015AbstractIntroductionAlthough susceptibility genes for anti-citrullinated peptide/protein antibodies (ACPA)-positive rheumatoid arthritis (RA) have been successfully discovered by genome-wide association studies (GWAS), little is known about
rheumatoid arthritis 15491 three genome-wide association studies (GWAS) for anti-citrullinated peptide/protein antibody-negative rheumatoid arthritis . The horizontal line indicates the GWAS significance level (P = 5 × 10−8).Next, we performed
rheumatoid arthritis 17420 (0.75, 0.90)0SNP, single nucleotide polymorphism; ACPA, anti-citrullinated peptide/protein antibody; RA, rheumatoid arthritis ; GWAS, genome-wide association studies; OR, odds ratio; Chr, chromosome; Ref, reference; Var, variance;
rheumatoid arthritis 18699 susceptibility loci with ACPA-positive RA (Figure 2B).Figure 2Correlation of odds ratios (ORs) of rheumatoid arthritis (RA) susceptibility single nucleotide polymorphisms (SNPs) for anti-citrullinated peptide/protein antibody
rheumatoid arthritis 21353 single nucleotide polymorphisms (SNPs) among anti-citrullinated peptide/protein antibody (ACPA)-positive rheumatoid arthritis (RA) and the two subsets of ACPA-negative RA. Correlation coefficient of ORs between ACPA-positive RA

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