Mycobacterium Avium complex vertebral osteomyelitis in the absence of HIV infection: a case report and review.

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Term Occurence Count Dictionary
ethambutol 19 infectiousdiseasesdrugs
isoniazid 4 infectiousdiseasesdrugs
rifabutin 1 infectiousdiseasesdrugs
AIDS 5 infectiousdiseases
abscess 20 infectiousdiseases
chloroquine 2 infectiousdiseasesdrugs
hydroxychloroquine 2 infectiousdiseasesdrugs
moxifloxacin 1 infectiousdiseasesdrugs
tuberculosis 3 infectiousdiseases
clarithromycin 13 infectiousdiseasesdrugs
clindamycin 1 infectiousdiseasesdrugs
erythromycin 1 infectiousdiseasesdrugs
amikacin 2 infectiousdiseasesdrugs
clofazimine 1 infectiousdiseasesdrugs
herpes zoster 1 infectiousdiseases
ciprofloxacin 2 infectiousdiseasesdrugs
cycloserine 3 infectiousdiseasesdrugs
ofloxacin 2 infectiousdiseasesdrugs
pyrazinamide 2 infectiousdiseasesdrugs
streptomycin 3 infectiousdiseasesdrugs
azithromycin 2 infectiousdiseasesdrugs
aztreonam 1 infectiousdiseasesdrugs
cefepime 1 infectiousdiseasesdrugs
vancomycin 1 infectiousdiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
amikacin 9839 lung mass with pleural effusion.Initial empiric: Isoniazid, rifampin, pyrazinamide/2.25Definitive: amikacin /4, clindamycin, clofazamine, ethambutol, rifampin/6 - until deathYes(Acid fast stain lead to TB diagnosis)
amikacin 10475 osteomyelitis with psoas abscessInitial empiric: ethambutol, isoniazid, pyrazinamide, rifampicin/3.Definitive: amikacin /2, ethambutol, rifampicin/12Yes(Pathology lead to TB diagnosis)Tissue culture/12119Japan67, MLow back
azithromycin 6898 to clofazimine, rifabutin, clarithromycin, ethambutol, and rifampin. Treatment with ethambutol and azithromycin was initiated after receiving susceptibility results. Two-drug therapy was selected due to the favorable
azithromycin 17665 regimen is required as monotherapy has been shown to increase resistance [[2], [23]]. Clarithromycin and azithromycin have both proven to be effective in combination regimens, though clarithromycin did show more rapid
aztreonam 5754 Cefepime was considered as a possible etiology of her altered mental status and therefore was replaced by aztreonam . Admission vital signs were unremarkable. C-reactive protein and sedimentation rate were 4.9 mg/dL
cefepime 5476 and QuantiFERON®-TB Gold In-Tube testing were also negative. Empiric treatment with vancomycin and cefepime was initiated with plans to complete a six-week course.Three weeks after surgical intervention, she
chloroquine 4236 laminectomy 2 years prior, and systemic lupus erythematosus (SLE) with ongoing therapy with hydroxy chloroquine and prednisone 20 mg daily. Her low back pain initially manifested in the context of a herpes zoster
chloroquine 11382 diagnosis)Tissue culture/NA126U.S.A.27, FLow back pain, fevers, LE weakness and hyporeflexiaSLE, steroid, hydroxy chloroquine useL5 osteomyelitis, soft tissue mass extending into spinal canal and anteriorly into retroperitoneum,
ciprofloxacin 11737 MLow back pain, paraplegiaNoneT6 and T7 destruction, paraspinal abscess with spinal cord impingement. ciprofloxacin , erythromycin, ethambutol/6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary
ciprofloxacin 12080 sternum, and distal radiusInitial empiric: clarithromycin, isoniazid, pyridoxine, rifampinDefinitive: ciprofloxacin , clarithromycin, cycloserine, ethambutol, rifampin/24No(Acid-fast stain from abscesses lead to TB diagnosis)Tissue
clarithromycin 6826 susceptibility testing indicated a favorable resistance profile with susceptibility to clofazimine, rifabutin, clarithromycin , ethambutol, and rifampin. Treatment with ethambutol and azithromycin was initiated after receiving
clarithromycin 8942 sensationPolymyositis, steroid useT11-L1 osteomyelitis, extra-dural soft tissue mass compressing anterior spinal cord clarithromycin , ethambutol, rifampin/NANo(Acid fast stain lead to TB diagnosis)Tissue culture/ NA110U.S.A.62, FLow
clarithromycin 9149 NA110U.S.A.62, FLow back painNoneParaspinal abscess at L5-S1, destructive changes of L5 and S1 vertebral bodies. clarithromycin , clofazamine, ethambutol/21YesTissue culture/NA111U.S.A.35, MRight shoulder painSLE, steroid useRight
clarithromycin 9498 deathYesTissue culture/NA112Japan76, FMAC pulmonary infection, low back painNoneT4-T5 osteomyelitis clarithromycin , moxifloxacin, rifampicin/NAYesTissue culture/NA113U.S.A.79, MLow back pain, urinary incontinenceSLE,
clarithromycin 10098 painSLE, steroid useSeptic arthritis of bilateral knees, T8-T9 paravertebral abscess and T9 osteomyelitis clarithromycin , ethambutol, rifampin/12YesTissue culture/NA117Japan50, MLow back painNoneParavertebral abscess and
clarithromycin 10266 culture/NA117Japan50, MLow back painNoneParavertebral abscess and psoas abscess at level of L4, osteodiscitis at L2-L5. clarithromycin , ethambutol, rifampin/+ 12YesTissue culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with
clarithromycin 10651 diagnosis)Tissue culture/12119Japan67, MLow back pain, feverDiabetes mellitusT spine to L spine with psoas abscess clarithromycin , cycloserine, ethambutol, rifampicin, streptomycin sulfate/+ 24YesPCR* from sinus tract/8120Australia70,
clarithromycin 10877 back pain, paraplegiaOsteoporosis, chronic bronchitisT12 osteomyelitis with spinal cord compression clarithromycin , ethambutol, rifampin/NANoTissue culture/2221U.S.A.60, FLow back pain, fevers, productive coughSarcoidosis,
clarithromycin 11139 splenectomyT7-T9 osteomyelitis with paraspinal abscess causing cord compression at T8-T9.Initial empiric: clarithromycin , ethambutol, isoniazid, rifampin.Definitive: clarithromycin, ethambutol, rifampin/24Yes(Acid-fast stain
clarithromycin 11199 cord compression at T8-T9.Initial empiric: clarithromycin, ethambutol, isoniazid, rifampin.Definitive: clarithromycin , ethambutol, rifampin/24Yes(Acid-fast stain lead to TB diagnosis)Tissue culture/NA126U.S.A.27, FLow
clarithromycin 12021 abscess, metastatic osteomyelitis to proximal femurs, pelvis, sternum, and distal radiusInitial empiric: clarithromycin , isoniazid, pyridoxine, rifampinDefinitive: ciprofloxacin, clarithromycin, cycloserine, ethambutol,
clarithromycin 12095 distal radiusInitial empiric: clarithromycin, isoniazid, pyridoxine, rifampinDefinitive: ciprofloxacin, clarithromycin , cycloserine, ethambutol, rifampin/24No(Acid-fast stain from abscesses lead to TB diagnosis)Tissue culture/NA129U.S.A.12,
clarithromycin 17743 [23]]. Clarithromycin and azithromycin have both proven to be effective in combination regimens, though clarithromycin did show more rapid clearance in patients with bacteremia [[2]]. Ethambutol is the generally the second
clindamycin 9851 with pleural effusion.Initial empiric: Isoniazid, rifampin, pyrazinamide/2.25Definitive: amikacin/4, clindamycin , clofazamine, ethambutol, rifampin/6 - until deathYes(Acid fast stain lead to TB diagnosis) Tissue culture/9217Japan38,
clofazimine 6802 probe. In vitro susceptibility testing indicated a favorable resistance profile with susceptibility to clofazimine , rifabutin, clarithromycin, ethambutol, and rifampin. Treatment with ethambutol and azithromycin was
cycloserine 10667 culture/12119Japan67, MLow back pain, feverDiabetes mellitusT spine to L spine with psoas abscessclarithromycin, cycloserine , ethambutol, rifampicin, streptomycin sulfate/+ 24YesPCR* from sinus tract/8120Australia70, FLow back
cycloserine 11516 soft tissue mass extending into spinal canal and anteriorly into retroperitoneum, 1 cm breast nodule cycloserine , ethambutol, rifampin, streptomycin/20 months – until death.YesTissue culture from breast/NA127U.S.A.39,
cycloserine 12111 empiric: clarithromycin, isoniazid, pyridoxine, rifampinDefinitive: ciprofloxacin, clarithromycin, cycloserine , ethambutol, rifampin/24No(Acid-fast stain from abscesses lead to TB diagnosis)Tissue culture/NA129U.S.A.12,
erythromycin 11752 paraplegiaNoneT6 and T7 destruction, paraspinal abscess with spinal cord impingement.ciprofloxacin, erythromycin , ethambutol/6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary abscess, sternal
ethambutol 1552 weeks of admission. MAC eventually grew from culture 14 days after collection. She was treated with ethambutol and rifampin and her symptoms resolved in 2 weeks, though therapy was continued for 12 months.ConclusionsMAC
ethambutol 6842 indicated a favorable resistance profile with susceptibility to clofazimine, rifabutin, clarithromycin, ethambutol , and rifampin. Treatment with ethambutol and azithromycin was initiated after receiving susceptibility
ethambutol 6883 susceptibility to clofazimine, rifabutin, clarithromycin, ethambutol, and rifampin. Treatment with ethambutol and azithromycin was initiated after receiving susceptibility results. Two-drug therapy was selected
ethambutol 8958 useT11-L1 osteomyelitis, extra-dural soft tissue mass compressing anterior spinal cordclarithromycin, ethambutol , rifampin/NANo(Acid fast stain lead to TB diagnosis)Tissue culture/ NA110U.S.A.62, FLow back painNoneParaspinal
ethambutol 9178 painNoneParaspinal abscess at L5-S1, destructive changes of L5 and S1 vertebral bodies.clarithromycin, clofazamine, ethambutol /21YesTissue culture/NA111U.S.A.35, MRight shoulder painSLE, steroid useRight humeral head osteomyelitis,
ethambutol 9352 steroid useRight humeral head osteomyelitis, thoracolumbar infection with associated paraspinal abscess ethambutol , isoniazid, streptomycin/24+, until deathYesTissue culture/NA112Japan76, FMAC pulmonary infection, low
ethambutol 9877 effusion.Initial empiric: Isoniazid, rifampin, pyrazinamide/2.25Definitive: amikacin/4, clindamycin, clofazamine, ethambutol , rifampin/6 - until deathYes(Acid fast stain lead to TB diagnosis) Tissue culture/9217Japan38, FLow
ethambutol 10114 useSeptic arthritis of bilateral knees, T8-T9 paravertebral abscess and T9 osteomyelitisclarithromycin, ethambutol , rifampin/12YesTissue culture/NA117Japan50, MLow back painNoneParavertebral abscess and psoas abscess
ethambutol 10282 painNoneParavertebral abscess and psoas abscess at level of L4, osteodiscitis at L2-L5.clarithromycin, ethambutol , rifampin/+ 12YesTissue culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with psoas abscessInitial
ethambutol 10413 rifampin/+ 12YesTissue culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with psoas abscessInitial empiric: ethambutol , isoniazid, pyrazinamide, rifampicin/3.Definitive: amikacin/2, ethambutol, rifampicin/12Yes(Pathology
ethambutol 10487 psoas abscessInitial empiric: ethambutol, isoniazid, pyrazinamide, rifampicin/3.Definitive: amikacin/2, ethambutol , rifampicin/12Yes(Pathology lead to TB diagnosis)Tissue culture/12119Japan67, MLow back pain, feverDiabetes
ethambutol 10680 back pain, feverDiabetes mellitusT spine to L spine with psoas abscessclarithromycin, cycloserine, ethambutol , rifampicin, streptomycin sulfate/+ 24YesPCR* from sinus tract/8120Australia70, FLow back pain, paraplegiaOsteoporosis,
ethambutol 10893 paraplegiaOsteoporosis, chronic bronchitisT12 osteomyelitis with spinal cord compressionclarithromycin, ethambutol , rifampin/NANoTissue culture/2221U.S.A.60, FLow back pain, fevers, productive coughSarcoidosis, steroid
ethambutol 11155 osteomyelitis with paraspinal abscess causing cord compression at T8-T9.Initial empiric: clarithromycin, ethambutol , isoniazid, rifampin.Definitive: clarithromycin, ethambutol, rifampin/24Yes(Acid-fast stain lead to
ethambutol 11215 T8-T9.Initial empiric: clarithromycin, ethambutol, isoniazid, rifampin.Definitive: clarithromycin, ethambutol , rifampin/24Yes(Acid-fast stain lead to TB diagnosis)Tissue culture/NA126U.S.A.27, FLow back pain, fevers,
ethambutol 11529 mass extending into spinal canal and anteriorly into retroperitoneum, 1 cm breast nodulecycloserine, ethambutol , rifampin, streptomycin/20 months – until death.YesTissue culture from breast/NA127U.S.A.39, MLow
ethambutol 11766 paraplegiaNoneT6 and T7 destruction, paraspinal abscess with spinal cord impingement.ciprofloxacin, erythromycin, ethambutol /6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary abscess, sternal abscess,
ethambutol 12124 clarithromycin, isoniazid, pyridoxine, rifampinDefinitive: ciprofloxacin, clarithromycin, cycloserine, ethambutol , rifampin/24No(Acid-fast stain from abscesses lead to TB diagnosis)Tissue culture/NA129U.S.A.12, FLeft
ethambutol 18445 pharmacotherapies have potential associated adverse effects. While macrolides are generally well-tolerated, use of ethambutol can lead to serious optic neuropathies. The rifamycins are inducers of the cytochrome P-450 oxidative
hydroxychloroquine 4229 cyclophosphamide, L3 laminectomy 2 years prior, and systemic lupus erythematosus (SLE) with ongoing therapy with hydroxychloroquine and prednisone 20 mg daily. Her low back pain initially manifested in the context of a herpes zoster
hydroxychloroquine 11375 diagnosis)Tissue culture/NA126U.S.A.27, FLow back pain, fevers, LE weakness and hyporeflexiaSLE, steroid, hydroxychloroquine useL5 osteomyelitis, soft tissue mass extending into spinal canal and anteriorly into retroperitoneum,
isoniazid 9364 useRight humeral head osteomyelitis, thoracolumbar infection with associated paraspinal abscessethambutol, isoniazid , streptomycin/24+, until deathYesTissue culture/NA112Japan76, FMAC pulmonary infection, low back painNoneT4-T5
isoniazid 10425 culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with psoas abscessInitial empiric: ethambutol, isoniazid , pyrazinamide, rifampicin/3.Definitive: amikacin/2, ethambutol, rifampicin/12Yes(Pathology lead to TB
isoniazid 11167 with paraspinal abscess causing cord compression at T8-T9.Initial empiric: clarithromycin, ethambutol, isoniazid , rifampin.Definitive: clarithromycin, ethambutol, rifampin/24Yes(Acid-fast stain lead to TB diagnosis)Tissue
isoniazid 12037 osteomyelitis to proximal femurs, pelvis, sternum, and distal radiusInitial empiric: clarithromycin, isoniazid , pyridoxine, rifampinDefinitive: ciprofloxacin, clarithromycin, cycloserine, ethambutol, rifampin/24No(Acid-fast
moxifloxacin 9514 culture/NA112Japan76, FMAC pulmonary infection, low back painNoneT4-T5 osteomyelitisclarithromycin, moxifloxacin , rifampicin/NAYesTissue culture/NA113U.S.A.79, MLow back pain, urinary incontinenceSLE, steroid use,
ofloxacin 11741 back pain, paraplegiaNoneT6 and T7 destruction, paraspinal abscess with spinal cord impingement.cipr ofloxacin , erythromycin, ethambutol/6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary
ofloxacin 12084 sternum, and distal radiusInitial empiric: clarithromycin, isoniazid, pyridoxine, rifampinDefinitive: cipr ofloxacin , clarithromycin, cycloserine, ethambutol, rifampin/24No(Acid-fast stain from abscesses lead to TB diagnosis)Tissue
pyrazinamide 9810 tissue paraspinal mass. 10 cm lung mass with pleural effusion.Initial empiric: Isoniazid, rifampin, pyrazinamide /2.25Definitive: amikacin/4, clindamycin, clofazamine, ethambutol, rifampin/6 - until deathYes(Acid fast
pyrazinamide 10436 culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with psoas abscessInitial empiric: ethambutol, isoniazid, pyrazinamide , rifampicin/3.Definitive: amikacin/2, ethambutol, rifampicin/12Yes(Pathology lead to TB diagnosis)Tissue
rifabutin 6815 susceptibility testing indicated a favorable resistance profile with susceptibility to clofazimine, rifabutin , clarithromycin, ethambutol, and rifampin. Treatment with ethambutol and azithromycin was initiated
streptomycin 9375 head osteomyelitis, thoracolumbar infection with associated paraspinal abscessethambutol, isoniazid, streptomycin /24+, until deathYesTissue culture/NA112Japan76, FMAC pulmonary infection, low back painNoneT4-T5 osteomyelitisclarithromycin,
streptomycin 10704 feverDiabetes mellitusT spine to L spine with psoas abscessclarithromycin, cycloserine, ethambutol, rifampicin, streptomycin sulfate/+ 24YesPCR* from sinus tract/8120Australia70, FLow back pain, paraplegiaOsteoporosis, chronic
streptomycin 11551 spinal canal and anteriorly into retroperitoneum, 1 cm breast nodulecycloserine, ethambutol, rifampin, streptomycin /20 months – until death.YesTissue culture from breast/NA127U.S.A.39, MLow back pain, paraplegiaNoneT6
vancomycin 5461 stains, cultures and QuantiFERON®-TB Gold In-Tube testing were also negative. Empiric treatment with vancomycin and cefepime was initiated with plans to complete a six-week course.Three weeks after surgical intervention,
Select Disease Character Offset Disease Term Instance
AIDS 624 osteomyelitis is less common, and is particularly rare in the absence of Acquired Immunodeficiency Syndrome ( AIDS ). Prompt diagnosis of MAC vertebral osteomyelitis is challenging, but necessary to prevent serious morbidity
AIDS 1737 continued for 12 months.ConclusionsMAC is an unusual cause of vertebral osteomyelitis in patients with AIDS , but is exceedingly rare in those without severe immune compromise. Despite its rarity, it must be considered
AIDS 3469 in the medical literature are presented in hosts affected by Human Immunodeficiency Virus (HIV) or AIDS [[4]–[8]], though there are reports of MAC osteomyelitis in HIV infected patients with immune reconstitution
AIDS 7569 osteomyelitis in non-HIV infected individuals in the literature to date (Table 1). As discussed, HIV/ AIDS is a risk factor for MAC infection as are other forms of immunosuppression related to medications or
AIDS 20101 likely required.ConclusionVertebral osteomyelitis is a rare manifestation of MAC in persons with HIV or AIDS , but is even less common in persons without immunocompromising conditions. Chronic corticosteroid therapy
abscess 1065 pain. Upon presentation, imaging revealed osteomyelitis of the lumbar spine with associated paraspinal abscess . Cultures from the surgical evacuation of the paraspinal abscess yielded no pathogen growth and she
abscess 1130 lumbar spine with associated paraspinal abscess. Cultures from the surgical evacuation of the paraspinal abscess yielded no pathogen growth and she was therefore treated with empiric antibacterial therapy. Two weeks
abscess 4590 conservative management. Magnetic Resonance Imaging (MRI) of the lumbar spine showed evidence of an epidural abscess at L2–3, L3–4 with vertebral osteomyelitis at L2-L3. Admission vitals showed a heart rate of 120
abscess 5065 elevated at 2.8 mg/dL and 45 mm/h respectively. She underwent surgical evacuation of the epidural abscess and wound revision of L2-L3. Intra-operative findings included dark brown fluid that egressed from her
abscess 6177 of L2-L3 and the vertebral body of L4. There were also findings consistent with a large paraspinal abscess anterior to the L3 vertebral body. A biopsy of the L3 vertebral body was obtained and showed no organisms
abscess 9081 rifampin/NANo(Acid fast stain lead to TB diagnosis)Tissue culture/ NA110U.S.A.62, FLow back painNoneParaspinal abscess at L5-S1, destructive changes of L5 and S1 vertebral bodies.clarithromycin, clofazamine, ethambutol/21YesTissue
abscess 9345 painSLE, steroid useRight humeral head osteomyelitis, thoracolumbar infection with associated paraspinal abscess ethambutol, isoniazid, streptomycin/24+, until deathYesTissue culture/NA112Japan76, FMAC pulmonary infection,
abscess 10070 culture/9217Japan38, FLow back painSLE, steroid useSeptic arthritis of bilateral knees, T8-T9 paravertebral abscess and T9 osteomyelitisclarithromycin, ethambutol, rifampin/12YesTissue culture/NA117Japan50, MLow back
abscess 10201 osteomyelitisclarithromycin, ethambutol, rifampin/12YesTissue culture/NA117Japan50, MLow back painNoneParavertebral abscess and psoas abscess at level of L4, osteodiscitis at L2-L5.clarithromycin, ethambutol, rifampin/+ 12YesTissue
abscess 10219 ethambutol, rifampin/12YesTissue culture/NA117Japan50, MLow back painNoneParavertebral abscess and psoas abscess at level of L4, osteodiscitis at L2-L5.clarithromycin, ethambutol, rifampin/+ 12YesTissue culture/5118China60,
abscess 10389 ethambutol, rifampin/+ 12YesTissue culture/5118China60, MLow back painNoneL2-L3 osteomyelitis with psoas abscess Initial empiric: ethambutol, isoniazid, pyrazinamide, rifampicin/3.Definitive: amikacin/2, ethambutol,
abscess 10644 diagnosis)Tissue culture/12119Japan67, MLow back pain, feverDiabetes mellitusT spine to L spine with psoas abscess clarithromycin, cycloserine, ethambutol, rifampicin, streptomycin sulfate/+ 24YesPCR* from sinus tract/8120Australia70,
abscess 11080 productive coughSarcoidosis, steroid use, COPD, osteoporosis, splenectomyT7-T9 osteomyelitis with paraspinal abscess causing cord compression at T8-T9.Initial empiric: clarithromycin, ethambutol, isoniazid, rifampin.Definitive:
abscess 11700 culture from breast/NA127U.S.A.39, MLow back pain, paraplegiaNoneT6 and T7 destruction, paraspinal abscess with spinal cord impingement.ciprofloxacin, erythromycin, ethambutol/6YesTissue culture/NA128U.S.A.31,
abscess 11854 erythromycin, ethambutol/6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary abscess , sternal abscess, T7-T8 osteomyelitis with paraspinal abscess, metastatic osteomyelitis to proximal
abscess 11871 ethambutol/6YesTissue culture/NA128U.S.A.31, FBack pain, painful adenopathyNoneAxillary abscess, sternal abscess , T7-T8 osteomyelitis with paraspinal abscess, metastatic osteomyelitis to proximal femurs, pelvis, sternum,
abscess 11916 pain, painful adenopathyNoneAxillary abscess, sternal abscess, T7-T8 osteomyelitis with paraspinal abscess , metastatic osteomyelitis to proximal femurs, pelvis, sternum, and distal radiusInitial empiric: clarithromycin,
abscess 12171 rifampinDefinitive: ciprofloxacin, clarithromycin, cycloserine, ethambutol, rifampin/24No(Acid-fast stain from abscess es lead to TB diagnosis)Tissue culture/NA129U.S.A.12, FLeft leg painNoneMultifocal osteomyelitis involving
abscess 16976 osteomyelitis include both surgical and medical interventions. MAC vertebral osteomyelitis can often lead to abscess formation and/or fistulous tracts, likely due to delay in diagnosis and definitive treatment. Indications
abscess 17123 likely due to delay in diagnosis and definitive treatment. Indications for surgical debridement include abscess formation, progressive destruction of vertebral bodies or neurologic compromise. There are no consensus
herpes zoster 4336 hydroxychloroquine and prednisone 20 mg daily. Her low back pain initially manifested in the context of a herpes zoster infection and management of presumed neuropathic pain was pursued. In ensuing months, she had progression
tuberculosis 12661 obstructive pulmonary disease, ILD interstitial lung disease, NA data not available, TB Mycobacterium tuberculosis , PCR polymerase chain reactionIdentifying the mode of transmission in patients with MAC infection is
tuberculosis 16404 without additional positivity from histopathologic stains or cultures. Though empiric treatment of tuberculosis is recommended in cases with evidence of mycobacterial infection, in these cases it has led to increased
tuberculosis 16579 infection, in these cases it has led to increased morbidity given MAC’s inherent resistance of many anti- tuberculosis agents [[9], [13], [18], [21]]. As AFB stains do not differentiate between tuberculous and non-tuberculous

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