Neutralizing Monoclonal Antibodies as Promising Therapeutics against Middle East Respiratory Syndrome Coronavirus Infection

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pneumonia 2 infectiousdiseases

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pneumonia 1572 IntroductionMiddle East Respiratory Syndrome (MERS) emerged in 2012 in Saudi Arabia with the death of a man with pneumonia ; the causative agent was subsequently identified as MERS-CoV, which belonged to lineage C betacoronaviruses
pneumonia 22872 only showed transient lower respiratory infection [[46]], while common marmoset developed progressive pneumonia [[47]]; hDPP4-trangenic mouse expressed hDPP4 extensively, and resulted in multiple organ damage [[48]];

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