Increasing evidence of low lymphatic filariasis prevalence in high risk Loa loa areas in Central and West Africa: a literature review.

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Term Occurence Count Dictionary
filariasis 8 infectiousdiseases
ivermectin 4 infectiousdiseasesdrugs
loiasis 5 infectiousdiseases
malaria 5 infectiousdiseases
onchocerciasis 1 infectiousdiseases

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Select Drug Character Offset Drug Term Instance
ivermectin 652 for the elimination of lymphatic filariasis (LF). Due to the risk of severe adverse events (SAEs) to ivermectin in individuals with high L. loa microfilaraemia, the current strategy recommended by the World Health
ivermectin 2909 transmission with mass drug administration (MDA) using different regimen combinations of albendazole, ivermectin and diethylcarbamazine (DEC), and second by alleviating suffering through morbidity management and disability
ivermectin 4192 Central and West Africa (Fig. 1a) [[6]] and poses two problems for LF elimination. First, the use of ivermectin presents a risk of severe adverse events (SAEs) to individuals with high L. loa parasitaemias, i.e.
ivermectin 18904 used in these areas will be critical. The widespread distribution of community-directed treatment with ivermectin (CDTI) for onchocerciasis control may have impacted W. bancrofti transmission as shown elsewhere [[44],
Select Disease Character Offset Disease Term Instance
filariasis 63 Title: Parasites & VectorsIncreasing evidence of low lymphatic filariasis prevalence in high risk Loa loa areas in Central and West Africa: a literature reviewLouise A. Kelly-HopeJanet
filariasis 584 to implement the appropriate strategies to scale-up interventions for the elimination of lymphatic filariasis (LF). Due to the risk of severe adverse events (SAEs) to ivermectin in individuals with high L. loa
filariasis 2456 appropriate use of the limited resources and drug donations available for LF elimination.BackgroundLymphatic filariasis (LF) is a disabling parasitic disease transmitted by mosquitoes [[1]]. It is targeted for elimination
filariasis 6827 Google online sources. Search terms, and combinations thereof, included Wuchereria bancrofti, lymphatic filariasis , elephantiasis, Loa loa, loiasis, and tropical eye worm. Further sources of information were found within
filariasis 14609 films taken in the Cameroons.” (~1950s; Cameroon) [[33]]✓ “In most of Belgian Congo, however, filariasis seems to be rare and unimportant.” (~1950s; Belgian Congo) [[30]]✓ “… in 1924, an extensive
filariasis 15214 villages were all hyperendemic for loiasis. … The low prevalence of hydroceles suggests that lymphatic filariasis is not endemic in this study area.” (~2000s; Cameroon) [[34]]✓ “According to Languillon (1957)
filariasis 16201 [[38]]✓ “For the Gabonese population one can approximately say that 3 out of 5 adult patients have filariasis , two being D. perstans and one L. loa. Consequently, these affections represent a major public health
filariasis 16373 affections represent a major public health problem. Finally, one must note that no cases of lymphatic filariasis has been identified.” (~ 1980s; Gabon) [[39]]✓ “Because only a few infections were identified
loiasis 4049 co-endemicity with the filarial parasite Loa loa, which causes the disease known as Tropical eye worm or loiasis .Loa loa occurs in 10 countries in Central and West Africa (Fig. 1a) [[6]] and poses two problems for
loiasis 4962 reacting to L. loa when densities were > 15,00 Mf/ml and > 30,000 Mf/ml respectively [[13]].Fig. 1Maps of loiasis prevalence and study areas with low LF risk. a Loiasis prevalence. b Loiasis high risk and LF low riskThe
loiasis 6337 [15]].Geographical area and search strategyHigh risk L. loa areas were defined as those with > 40% loiasis prevalence determined by the Rapid Assessment Procedure for Loiasis (RAPLOA) [[18], [19]], which correlates
loiasis 6863 combinations thereof, included Wuchereria bancrofti, lymphatic filariasis, elephantiasis, Loa loa, loiasis , and tropical eye worm. Further sources of information were found within reference section of documents.
loiasis 15144 the Bankim district, located in the Tikar plain, the 10 surveyed villages were all hyperendemic for loiasis . … The low prevalence of hydroceles suggests that lymphatic filariasis is not endemic in this study
malaria 2293 of point-of-care test-and-treat options into health systems, and consolidating closer links with the malaria control programme may be a more effective and appropriate use of the limited resources and drug donations
malaria 5366 insecticide-treated/long-lasting bednets (ITNs/LLINs), which control Anopheles mosquitoes that transmit both LF and malaria [[14]]. In addition, a basic five step model for national LF programmes to work at implementation unit
malaria 19091 transmission as shown elsewhere [[44], [45]]. Similarly, the recent significant scale-up of vector control for malaria , primarily ITNs/LLINs, which has reduced malaria prevalence [[46]], may have reduced W. bancrofti prevalence,
malaria 19140 recent significant scale-up of vector control for malaria, primarily ITNs/LLINs, which has reduced malaria prevalence [[46]], may have reduced W. bancrofti prevalence, as also demonstrated elsewhere [[47], [48]].
malaria 19496 integrating point-of-care test-and-treat options into health systems and consolidating closer links with the malaria control programme, may be a better use of the limited resources available for LF elimination programmes
onchocerciasis 18926 be critical. The widespread distribution of community-directed treatment with ivermectin (CDTI) for onchocerciasis control may have impacted W. bancrofti transmission as shown elsewhere [[44], [45]]. Similarly, the

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