Resveratrol as a Novel Anti-Herpes Simplex Virus Nutraceutical Agent: An Overview

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Term Occurence Count Dictionary
cidofovir 3 infectiousdiseasesdrugs
foscarnet 2 infectiousdiseasesdrugs
hepatitis C 1 infectiousdiseases
herpes simplex 3 infectiousdiseases
famciclovir 1 infectiousdiseasesdrugs
meningitis 1 infectiousdiseases
penciclovir 1 infectiousdiseasesdrugs
pneumonia 1 infectiousdiseases
valacyclovir 1 infectiousdiseasesdrugs
viral encephalitis 1 infectiousdiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Select Drug Character Offset Drug Term Instance
cidofovir 3477 the chain elongation. However, further antiviral agents have been developed, including foscarnet and cidofovir , as second-line therapies against drug-resistant HSV. Unlike first-generation anti-HSV agents, foscarnet
cidofovir 3810 site of the viral DNA polymerase, resulting in impeding normal viral replication. On the other side, cidofovir is a monophosphate analog that requires a phopshorilation independent of viral enzymes. The activated
cidofovir 3922 a monophosphate analog that requires a phopshorilation independent of viral enzymes. The activated cidofovir -diphosphate is incorporated into the nascent viral DNA strand, but it does not necessarily result in
famciclovir 3109 treatments consist of the use of nucleoside analogues, including acyclovir and its derivatives (penciclovir, famciclovir , and valacyclovir), which act by inhibiting the viral DNA polymerase, thus preventing viral DNA synthesis.
foscarnet 3463 termination of the chain elongation. However, further antiviral agents have been developed, including foscarnet and cidofovir, as second-line therapies against drug-resistant HSV. Unlike first-generation anti-HSV
foscarnet 3582 cidofovir, as second-line therapies against drug-resistant HSV. Unlike first-generation anti-HSV agents, foscarnet does not require any initial phopshorilation, but directly acts by binding to and blocking the pyrophosphate-binding
penciclovir 3096 These treatments consist of the use of nucleoside analogues, including acyclovir and its derivatives ( penciclovir , famciclovir, and valacyclovir), which act by inhibiting the viral DNA polymerase, thus preventing viral
valacyclovir 3126 use of nucleoside analogues, including acyclovir and its derivatives (penciclovir, famciclovir, and valacyclovir ), which act by inhibiting the viral DNA polymerase, thus preventing viral DNA synthesis. In general,
Select Disease Character Offset Disease Term Instance
hepatitis C 7441 evidence demonstrated the effect of RSV against a number of viruses, including the varicella zoster virus, hepatitis C virus, influenza virus, respiratory syncytial virus, human metapneumonia virus, Epstein–Barr virus,
herpes simplex 594 ettore.novellino@unina.it (E.N.)Publication date (epub): 9/2018Publication date (collection): 9/2018AbstractThe herpes simplex virus (HSV) is a common human virus affecting many people worldwide. HSV infections manifest with lesions
herpes simplex 1412 elucidating the efficacy of RSV against HSV and the main demonstrated mechanisms of action.1. IntroductionThe herpes simplex virus (HSV) is a common human, double-stranded DNA virus belonging to the Herpesviridae family, which
herpes simplex 26974 with HSV-1 and -2Oligomeric RSV derivativesAnti-HSV-1 and -2 activity by increasing ROS levels.HSV, herpes simplex virus; RSV, resveratrol; MRC, human lung cell line; NF-κB, nuclear factor kappa-light-chain-enhancer
meningitis 2198 serious, leading to significant morbidity and mortality and, in rare case, viral encephalitis, lymphocytic meningitis , or blindness [[1]].According to the World Health Organization, about 3.7 billion people under 50 years
pneumonia 7516 varicella zoster virus, hepatitis C virus, influenza virus, respiratory syncytial virus, human meta pneumonia virus, Epstein–Barr virus, enterovirus, African swine fever virus, duck enteritis virus, and HIV,
viral encephalitis 2166 infections can be particularly serious, leading to significant morbidity and mortality and, in rare case, viral encephalitis , lymphocytic meningitis, or blindness [[1]].According to the World Health Organization, about 3.7 billion

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