Nanoparticles for Signaling in Biodiagnosis and Treatment of Infectious Diseases

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Annotation Summary

Term Occurence Count Dictionary
diarrhea 1 infectiousdiseases
hepatitis A 1 infectiousdiseases
hepatitis B 4 infectiousdiseases
infectious disease 5 infectiousdiseases
pneumonia 5 infectiousdiseases
syphilis 1 infectiousdiseases
tuberculosis 7 infectiousdiseases
hepatitis C 1 infectiousdiseases
hepatitis E 1 infectiousdiseases
tobramycin 4 infectiousdiseasesdrugs
vancomycin 2 infectiousdiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Select Drug Character Offset Drug Term Instance
tobramycin 60340 suppress AHL production [[205]]. Other studies with liposomes combining bismuth–ethanedithiol with tobramycin also showed the superior ability of liposomes inhibiting the production of N-acyl homoserine lactone,
tobramycin 60593 and chitinase [[205],[206],[207],[208],[209],[210]]. Also, several niosome formulations, including tobramycin and bismuth-ethanedithiol, were evaluated both alone and in combination as drug delivery systems with
tobramycin 60984 incorporation in niosomes reduced the minimum inhibitory concentration (MIC) of formulations including tobramycin in comparison with the non-encapsulated ones. This has been attributed to an enhanced penetration of
tobramycin 61227 [[210]]. Furthermore, 1:2 MIC and 1:4 MIC concentrations of the free and niosomal bismuth-ethanedithiol tobramycin combinations were the most effective, inhibiting biofilm formation by over 80%. These two formulations
vancomycin 23256 bacteria due to the multivalent hydrogen binding effect. Mesoporous silica nanoparticles modified with vancomycin have been developed for the recognition and killing of Gram-positive bacteria. Mesopores of vancomycin
vancomycin 23359 vancomycin have been developed for the recognition and killing of Gram-positive bacteria. Mesopores of vancomycin silica nanoparticles were loaded with a fluorescent molecule (FITC). After incubation with FITC and
Select Disease Character Offset Disease Term Instance
diarrhea 18334 O157:H7 is a bacteria associated with food poisoning via the release of a toxin called Shiga that causes diarrhea and severe damage to the kidneys. Biosensors based on gold nanoparticles combined with polyclonal antibodies
hepatitis A 37322 target DNA sequences of different viruses, as has been demonstrated for the simultaneous detection of hepatitis A virus, hepatitis C virus, West Nile Virus, HIV and severe acute respiratory syndrome virus [[112]].Quantum
hepatitis B 34370 nanoparticles demonstrated their ultrasensitivity in detecting single-stranded DNA (ssDNA) of HPV and also hepatitis B virus (HBV) [[101]]. An electrode integrating graphene and polyaniline nanowires has also been proposed
hepatitis B 35983 also combined metallic nanoparticles with fluorescence enzyme-linked immunosorbent assay (FELISA) for hepatitis B diagnosis. Thus, by employing dually labeled gold nanoparticles, an enhancement in HBsAg detection limits
hepatitis B 41600 chemiluminescence detection is increased. An ultrasensitive method based on this system has been developed for the hepatitis B virus as a proof of concept [[85]], but it could be applied to other viruses.3.6. Other Applications
hepatitis B 42680 agents, improving their properties, as has been demonstrated for Fe3O4 nanoparticles encapsulated into hepatitis B core as a T2 MRI contrast imaging agent [[80]].3.7. Virus-Based Nanoparticles in Viral Genetic Material
hepatitis C 37341 of different viruses, as has been demonstrated for the simultaneous detection of hepatitis A virus, hepatitis C virus, West Nile Virus, HIV and severe acute respiratory syndrome virus [[112]].Quantum dots (QD) have
hepatitis E 40681 nanoparticles with reverse transcription loop-mediated isothermal amplification, a very simple assay for hepatitis E was developed, whose results can be evaluated with the naked eye due to color changes. It has been proposed
infectious disease 2094 developed for the control of infections associated with biofilm-associated infections.1. IntroductionCommon infectious disease s have been reasonably well controlled by a broad range of anti-infective agents, but recently, due to
infectious disease 3156 trials [[1],[3],[4],[5]].Advances in nanoparticle-based systems for the diagnosis and treatment of infectious disease s constitute a promising area of research with important implications for the treatment of bacterial
infectious disease 6241 played by molecular signaling via nanoparticles and nanomaterials in the diagnosis and treatment of infectious disease s.2. Nanoparticles for Bacterial DetectionTraditional methods used for the identification of bacteria
infectious disease 13504 [[34],[36]]. SERS tags are useful in biomedical imaging with potential application in cancer therapeutics and infectious disease s detection [[34],[37]].Label SERS functionalized with monoclonal antibodies incorporating different
infectious disease 28776 of even femtomolar amounts of virus [[81]]. Early diagnosis is always desirable for the control of infectious disease s. Different strategies have been implemented using nanoparticles to improve analytical technique characteristics,
pneumonia 15893 bacteria [[42]]. In addition, one specific label-free SERS method permits the identification of Klebsiella pneumonia e resistant strains. In this method, an aluminosilicate substrate with a 50 nm gold layer was used in
pneumonia 19939 electrodes have also recently been developed for the detection of bacteria such as E. coli and Streptococcus pneumonia e [[55],[56]]. This methodology is based on the adherence of metallic nanoparticles to the bacteria’s
pneumonia 20798 correlated with the amperometric response [[56]].In the same way, detection of pneumococcus such as S. pneumonia e has been carried out using electrical methods by measuring the change in electrical properties such
pneumonia 21251 interdigitated electrodes, the conductance change is correlated with the bacteria concentration. S. pneumonia e concentrations of about 10 CFU/ mL may be detected with this method [[55]].An alternative is to use
pneumonia 46918 simplest Gram-positive quorum sensing system was first discovered in Lactococcus lactis and Streptococcus pneumonia e [[152]]. A precursor of the auto-inducing peptide synthesized in the cell ribosome is modified and
syphilis 39404 on microfluidics and nanoparticles has been developed which allows diagnosis on-site of both HIV and syphilis . This device replicates the ELISA steps and allows the detection of antibody markers within scarcely
tuberculosis 9667 about 3 million people are estimated to remain undiagnosed or untreated. In addition, Mycobacterium tuberculosis strains are associated with higher morbidity and mortality in infected patients, making their prevention,
tuberculosis 9904 crucial [[27],[28]]. A magnetoresistive biosensor to detect Mycobacterium bovis (BCG) bacteria for tuberculosis diagnosis based on the use of magnetic nanoparticles has recently been developed [[29]]. This system
tuberculosis 10347 by the sensors [[29]]. This sensitive method is an alternative to classical methods of detecting of tuberculosis such as the Ziehl–Neelsen sputum smear microscopy image test for tuberculosis detection, which has
tuberculosis 10427 methods of detecting of tuberculosis such as the Ziehl–Neelsen sputum smear microscopy image test for tuberculosis detection, which has a poor sensitivity.In parallel, a magnetophoretic immunoassay sensor for early
tuberculosis 10553 which has a poor sensitivity.In parallel, a magnetophoretic immunoassay sensor for early diagnosis of tuberculosis in the culture supernatants from sputum samples has been developed. Antigens of Mycobacterium tuberculosis
tuberculosis 10660 tuberculosis in the culture supernatants from sputum samples has been developed. Antigens of Mycobacterium tuberculosis such as culture filtrate protein (CFP)-10 may be detected by this method. The system uses two different
tuberculosis 26916 cells [[68],[69]].FRET has recently been proposed for the detection and quantification of Mycobacterium tuberculosis DNA using gold nanoparticles and fluorometric detection [[70]].3. Nanoparticles for Viral DetectionDifferent

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