HTLV-1, ATLL, severe hypercalcaemia and HIV-1 co-infection: an overview

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Term Occurence Count Dictionary
tuberculosis 2 infectiousdiseases
zidovudine 2 infectiousdiseasesdrugs
AIDS 6 infectiousdiseases
lamivudine 1 infectiousdiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
lamivudine 6433 a detectable plasma viral load is seldom present in most cases [[5]]. Antiretroviral agents such as lamivudine , zidovudine and raltegravir have not shown clear benefit in patients with HTLV-1 infection [[23],[24]].ATLL:
zidovudine 6445 plasma viral load is seldom present in most cases [[5]]. Antiretroviral agents such as lamivudine, zidovudine and raltegravir have not shown clear benefit in patients with HTLV-1 infection [[23],[24]].ATLL: HTLV-1
zidovudine 7845 blood involvement [[27],[28]]. In terms of therapy, the best results are achieved with a combination of zidovudine , alpha interferon and chemotherapy. However the overall prognosis of ATLL is poor [[29]]. The median
Select Disease Character Offset Disease Term Instance
AIDS 1839 the possibility of HTLV-1 co-infection and its associated potential for accelerated progression to AIDS as well as the risk of developing adult T-cell lymphoma/leukemia (ATLL) or HTLV-associated myelopathy
AIDS 9215 HIV-1 has been reported as 4-23% in asymptomatic HIV infected persons and 5-28% in individuals with AIDS [[10],[33]-[35]]. In a study conducted in 1993 in Northern KwaZulu-Natal (KZN) that comprised 1018 subjects,
AIDS 11910 ATLL/HTLV-1 co-infection is evidenced by an increasing HIV-1 viral loads and clinical progression of AIDS despite a stable or rising CD4 cell count [[47]]. Therefore, in the HIV infected individual with ATLL
AIDS 14973 of HTLV-1 and its impact on CD4 lymphocyte counts (both absolute and relative), HIV viral load and AIDS progression in co-infected individuals in sub-Saharan Africa and other regions with a high HIV burden.
AIDS 15391 HIV-1 has been reported as 4-23% in asymptomatic HIV infected persons and 5-28% in individuals with AIDS ;The CD4 cell count must be interpreted with caution in the HIV-1 positive individual with concurrent
AIDS 15929 the possibility of HTLV-1 co-infection and its associated potential for accelerated progression to AIDS as well as the risk of developing adult T-cell lymphoma/leukemia (ATLL);The possibility of occult ATLL
tuberculosis 10396 [[11],[40]]. Persons co-infected with both HIV and HTLV-1 have a 2.5 fold higher risk of contracting tuberculosis , especially in countries with a high prevalence of tuberculosis, such as sub-Saharan Africa and Brazil.
tuberculosis 10460 2.5 fold higher risk of contracting tuberculosis, especially in countries with a high prevalence of tuberculosis , such as sub-Saharan Africa and Brazil. These patients also have a higher associated morbidity and mortality

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