Hepatitis E in High-Income Countries: What Do We Know? And What Are the Knowledge Gaps?

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Annotation Summary

Term Occurence Count Dictionary
hepatitis A 4 infectiousdiseases
hepatitis B 1 infectiousdiseases
hepatitis C 1 infectiousdiseases
ribavirin 2 infectiousdiseasesdrugs
viral hepatitis 1 infectiousdiseases

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Select Drug Character Offset Drug Term Instance
ribavirin 31878 recommendations for treating HEV infected patients with antiviral regimens. However, a combination of ribavirin and pegylated alpha interferon improved the condition of treated patients. The rapid clearance of HEV
ribavirin 32241 transplanted patients because of the risk of acute graft rejection.A multicenter study has shown that ribavirin may be effective in the treatment of chronic HEV infection; indeed, a three-month course seemed to be
Select Disease Character Offset Disease Term Instance
hepatitis A 5216 caused by the absence of viral antigens on the surface. These different forms were also found for the hepatitis A virus (HAV) [[21]].4. TaxonomyThe current taxonomy classifies HEV in the family Hepeviridae [[3]]. Since
hepatitis A 13344 strains belonging to four genotypes: HEV-1, HEV2, HEV3, and HEV-4. Symptoms are resembling those of hepatitis A . Clinical manifestations are similar in developing and industrialized countries [[70]]. The incubation
hepatitis A 14722 years [[77]]. The mortality rate is 1–4%, which is higher than the mortality associated with acute hepatitis A (0.1–2.5%) [[5]]. However, these rates are likely overestimated, because they were calculated from
hepatitis A 24205 Environmental WaterIn Italy, a study analyzed different types of samples (bivalves, water, and raw sewage) for hepatitis A virus and HEV [[145]]. HEV RNA was found in one sample of raw sewage and in one river sample; both isolates
hepatitis B 17512 Finally, HEV superinfection can aggravate previous liver diseases caused by alcohol, hepatitis C, or hepatitis B viruses [[112],[113]]. Superinfection must be evoked in the presence of a brutal marked elevation of
hepatitis C 17496 forms [[109]]. Finally, HEV superinfection can aggravate previous liver diseases caused by alcohol, hepatitis C , or hepatitis B viruses [[112],[113]]. Superinfection must be evoked in the presence of a brutal marked
viral hepatitis 1320 in developed countries.1. IntroductionHepatitis E virus (HEV) is one of the leading causes of acute viral hepatitis worldwide, and is responsible for 20 million infections and 70,000 deaths every year [[1]].Currently,

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