Burkholderia pseudomallei Adaptation for Survival in Stressful Conditions.

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Term Occurence Count Dictionary
melioidosis 16 infectiousdiseases
pneumonia 1 infectiousdiseases
abscess 2 infectiousdiseases
glanders 1 infectiousdiseases
infectious disease 1 infectiousdiseases

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abscess 3066 pneumonia, acute septicemia, and chronic localized infection [[4], [5]]. Chronic infection can cause abscess es in various internal organs, such as the lungs, liver, spleen, kidneys, prostate gland, and skeletal
abscess 31950 osmotic stress, ammonia accumulation, antibacterial agent exposure, the presence of nitric oxide, and abscess condition, will also contribute to our understanding of bacterial survival and persistence. Other bacterial
glanders 2752 pseudomallei was discovered in 1911 by Whitmore and his team as a bacterial agent associated with “ glanders -like” disease [[2]]. Many years later, this bacterium was proven to cause melioidosis [[4]]. This
infectious disease 1763 IntroductionBurkholderia pseudomallei is a Gram-negative bacterium that is the causative agent of melioidosis, an infectious disease of public-health significance in Southeast Asia and Northern Australia [[1], [2]]. In an endemic area,
melioidosis 547 /2018Publication date (epub): 5/2018AbstractBurkholderia pseudomallei is a Gram-negative bacterium that causes melioidosis , which can be fatal in humans. Melioidosis is prevalent in the tropical regions of Southeast Asia and
melioidosis 1620 which may lead to the development of novel strategies for the control, prevention, and treatment of melioidosis in the future.1. IntroductionBurkholderia pseudomallei is a Gram-negative bacterium that is the causative
melioidosis 1747 future.1. IntroductionBurkholderia pseudomallei is a Gram-negative bacterium that is the causative agent of melioidosis , an infectious disease of public-health significance in Southeast Asia and Northern Australia [[1],
melioidosis 1926 Asia and Northern Australia [[1], [2]]. In an endemic area, a mortality rate of 40% among septicemic melioidosis patients has been reported in Thailand [[3]]. In Australia, the mortality rate was about 21% [[3]].
melioidosis 2837 associated with “glanders-like” disease [[2]]. Many years later, this bacterium was proven to cause melioidosis [[4]]. This life-threatening disease presents with a wide range of nonspecific signs and symptoms, including
melioidosis 3442 thalassemia, or renal disease or people who work in paddy fields have been reported to have a higher risk of melioidosis [[7]]. However, healthy individuals with no obvious risk factors can also become infected, albeit with
melioidosis 3637 infected, albeit with significantly lower risk. Without appropriate treatment, the septicemic form of melioidosis can develop and is associated with >90% mortality rate [[2]]. Currently, no effective vaccine exists
melioidosis 3761 and is associated with >90% mortality rate [[2]]. Currently, no effective vaccine exists to prevent melioidosis .B. pseudomallei is found in a wide range of ecological niches, including soil and surface water, and
melioidosis 4315 environment. For example, many studies have demonstrated an association between the frequency of recorded melioidosis cases and rainfall-related events [[9]–[11]]. Merritt and Inglis suggested that the levels of cloud
melioidosis 8051 to survive for months or years in the environment is evident by the persistence of this bacterium in melioidosis -endemic areas [[8]]. Indeed, B. pseudomallei showed the ability to survive in adverse environments,
melioidosis 9794 for oxygen stress. Most of these stress-response proteins have been observed to react with sera from melioidosis patients [[39]], potentially indicating their important roles in the adaptation of bacteria to survive
melioidosis 10017 ecologically stressful conditions.3.1. Adaptation to Salt StressIn Thailand, the highest incidence of melioidosis and the highest prevalence of B. pseudomallei are found in the northeast, where saline soil and water
melioidosis 20953 conditions with increased iron stores, such as thalassemia, are considered to increase the risk of acquiring melioidosis . In Thai adults, thalassemia was associated with an 11-fold increase in melioidosis compared with other
melioidosis 21037 risk of acquiring melioidosis. In Thai adults, thalassemia was associated with an 11-fold increase in melioidosis compared with other patients with sepsis [[64]]. A recent study, reporting from the period from 2001
melioidosis 21211 study, reporting from the period from 2001 to 2010, showed that thalassemia was a major risk factor for melioidosis among Malaysian children [[65]]. Meanwhile, low-iron conditions were found to limit the growth of B.
melioidosis 31639 precise knowledge therefore opened the doors for novel targets for the treatment and prevention of melioidosis .The potential sources of stress encountered by B. pseudomallei are not limited to those reviewed here.
pneumonia 2965 life-threatening disease presents with a wide range of nonspecific signs and symptoms, including fever, pneumonia , acute septicemia, and chronic localized infection [[4], [5]]. Chronic infection can cause abscesses

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