Phytochemicals in Infections: What Are We Doing Now?

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Annotation Summary

Term Occurence Count Dictionary
metronidazole 4 infectiousdiseasesdrugs
ofloxacin 3 infectiousdiseasesdrugs
tetracycline 1 infectiousdiseasesdrugs
amoxicillin 4 infectiousdiseasesdrugs
ampicillin 1 infectiousdiseasesdrugs
ciprofloxacin 3 infectiousdiseasesdrugs
clarithromycin 7 infectiousdiseasesdrugs
diarrhea 1 infectiousdiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Having read the paper, please pick a pair of statements from the paper to indicate that a drug and disease are related.

Select Drug Character Offset Drug Term Instance
amoxicillin 8604 following: (A) bismuth subsalicylate, metronidazole, and tetracycline for 14 days; (B) omeprazole, amoxicillin , and clarithromycin for 10 days; and (C) lansoprazole, amoxicillin, and clarithromycin for either 10
amoxicillin 8671 tetracycline for 14 days; (B) omeprazole, amoxicillin, and clarithromycin for 10 days; and (C) lansoprazole, amoxicillin , and clarithromycin for either 10 or 14 days.Unfortunately, the heightening of antimicrobial resistance
amoxicillin 15805 with a dose of 93.5–500 mg/kg of H. celastroides extract in weight and 19 infected dogs receiving amoxicillin –clarithromycin–omeprazole (control treatment), the results showed effectiveness of 33.3 and 55%
amoxicillin 17426 pylori-infected mice treated with extract, palmatine, or control therapy (omeprazole, clarithromycin, and amoxicillin ), presented eradication ratios of, respectively, 80%, 50%, and 70%. The anti-H. pylori activity found
ampicillin 14153 colonization (4–5 × 105 colony forming unit (CFU)), being the antibacterial potential equivalent to of ampicillin used as positive control (10 µg/mL) (2–4 × 105 CFU) [[98]]. Time course viability experiments were
ciprofloxacin 14788 [[65]]. Also, H. pylori-inoculated Swiss mice receiving 125, 250, or 500 mg/kg of Bryophyllum pinnutum or ciprofloxacin (500 mg/kg) for 7 days, showed a significant reduction of H. pylori colonization on gastric tissue from
ciprofloxacin 15010 to 17%. In addition, the highest B. pinnatum extract tested (85.91 ± 52.91 CFU) and standard drug ciprofloxacin (25.74 ± 16.15 CFU) also reduced significantly (p < 0.05) the bacterial load of gastric mucosa as compared
ciprofloxacin 15285 [[74]]. On the other hand, Eryngium foetidum methanol extract (381.9 ± 239.5 CFU) and positive control ciprofloxacin (248 ± 153.2 CFU) significantly reduced the bacterial load in gastric mucosa at the same dose (500
clarithromycin 8621 bismuth subsalicylate, metronidazole, and tetracycline for 14 days; (B) omeprazole, amoxicillin, and clarithromycin for 10 days; and (C) lansoprazole, amoxicillin, and clarithromycin for either 10 or 14 days.Unfortunately,
clarithromycin 8688 (B) omeprazole, amoxicillin, and clarithromycin for 10 days; and (C) lansoprazole, amoxicillin, and clarithromycin for either 10 or 14 days.Unfortunately, the heightening of antimicrobial resistance has been associated
clarithromycin 15819 93.5–500 mg/kg of H. celastroides extract in weight and 19 infected dogs receiving amoxicillin– clarithromycin –omeprazole (control treatment), the results showed effectiveness of 33.3 and 55% in the experimental
clarithromycin 16244 pylori-infected mice into plant extract group, triple therapy control (lansoprazole, metronidazole, and clarithromycin ), blank control, and H. pylori control groups. The obtained eradication ratios, determined by rapid
clarithromycin 17406 up to 40 h. H. pylori-infected mice treated with extract, palmatine, or control therapy (omeprazole, clarithromycin , and amoxicillin), presented eradication ratios of, respectively, 80%, 50%, and 70%. The anti-H. pylori
clarithromycin 18300 mg/day); group VII (TASA + bismuth pectin); group VIII (TASA + omeprazole); group IX (bismuth pectin + clarithromycin + metronidazole); and group X (omeprazole + clarithromycin + metronidazole). The mice were sacrificed
clarithromycin 18359 omeprazole); group IX (bismuth pectin + clarithromycin + metronidazole); and group X (omeprazole + clarithromycin + metronidazole). The mice were sacrificed 4 weeks after treatment. Real-time PCR was used to detect
metronidazole 8543 of about 10–14 days, in which treatment regimens include the following: (A) bismuth subsalicylate, metronidazole , and tetracycline for 14 days; (B) omeprazole, amoxicillin, and clarithromycin for 10 days; and (C)
metronidazole 16225 randomly assigned H. pylori-infected mice into plant extract group, triple therapy control (lansoprazole, metronidazole , and clarithromycin), blank control, and H. pylori control groups. The obtained eradication ratios,
metronidazole 18317 (TASA + bismuth pectin); group VIII (TASA + omeprazole); group IX (bismuth pectin + clarithromycin + metronidazole ); and group X (omeprazole + clarithromycin + metronidazole). The mice were sacrificed 4 weeks after
metronidazole 18376 group IX (bismuth pectin + clarithromycin + metronidazole); and group X (omeprazole + clarithromycin + metronidazole ). The mice were sacrificed 4 weeks after treatment. Real-time PCR was used to detect 16sDNA of H. pylori
ofloxacin 14792 Also, H. pylori-inoculated Swiss mice receiving 125, 250, or 500 mg/kg of Bryophyllum pinnutum or cipr ofloxacin (500 mg/kg) for 7 days, showed a significant reduction of H. pylori colonization on gastric tissue from
ofloxacin 15014 17%. In addition, the highest B. pinnatum extract tested (85.91 ± 52.91 CFU) and standard drug cipr ofloxacin (25.74 ± 16.15 CFU) also reduced significantly (p < 0.05) the bacterial load of gastric mucosa as compared
ofloxacin 15289 On the other hand, Eryngium foetidum methanol extract (381.9 ± 239.5 CFU) and positive control cipr ofloxacin (248 ± 153.2 CFU) significantly reduced the bacterial load in gastric mucosa at the same dose (500
tetracycline 8562 days, in which treatment regimens include the following: (A) bismuth subsalicylate, metronidazole, and tetracycline for 14 days; (B) omeprazole, amoxicillin, and clarithromycin for 10 days; and (C) lansoprazole, amoxicillin,
Select Disease Character Offset Disease Term Instance
diarrhea 9181 comes with some degree of adverse effects, such as nausea, metallic taste, vomiting, skin rash, and diarrhea . Therefore, efforts are being channeled towards the development of effective treatments with few to

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