A rare case of Aerococcus urinae infective endocarditis in an atypically young male: case report and review of the literature

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Annotation Summary

Term Occurence Count Dictionary
penicillin G 1 infectiousdiseasesdrugs
septic shock 1 infectiousdiseases
abscess 1 infectiousdiseases
gentamicin 3 infectiousdiseasesdrugs
piperacillin 1 infectiousdiseasesdrugs
trimethoprim 2 infectiousdiseasesdrugs
vancomycin 3 infectiousdiseasesdrugs
meningitis 1 infectiousdiseases
ofloxacin 2 infectiousdiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

Review

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Select Drug Character Offset Drug Term Instance
gentamicin 1275 endocarditis (IE) who was successfully treated with mitral valve replacement and six weeks of penicillin/ gentamicin therapy. In addition, we include a comprehensive review of all reported cases of IE due to A. urinae
gentamicin 8078 infusion of penicillin G dosed at twenty-million units over twenty-four hours combined with once daily gentamicin dosed at 3 mg/kg. The patient’s post-operative course was uneventful. He remained inpatient for an
gentamicin 19016 of the A. urinae isolates tested failed to display a synergistic effect of combination beta-lactam gentamicin therapy [[5]].The largest case series of A. urinae IE treated fourteen patients with a median duration
ofloxacin 4221 one hundred thousand. He was subsequently discharged home with a fourteen day course of empiric Lev ofloxacin 500 mg once daily.On re-presentation, he denied the presence of genitourinary symptoms. Initial vital
ofloxacin 18160 presumably the initial nidus of infection. The patient presented was similarly treated with empiric Lev ofloxacin therapy. While there remains some question as to whether the original isolate was misidentified this
penicillin G 7987 With susceptibility results known, the antibiotic regimen was narrowed to a continuous infusion of penicillin G dosed at twenty-million units over twenty-four hours combined with once daily gentamicin dosed at 3 mg/kg.
piperacillin 5328 pulmonary edema and bilateral pleural effusions. The patient was started on empiric vancomycin and piperacillin -tazobactam antibiotic therapy. Despite hemodynamic stability at presentation, his cardiopulmonary status
trimethoprim 18489 inherently resistant to sulfonamides and previously thought to have similar inherent resistance to trimethoprim ; though recently, the methodology regarding the media used – where trimethoprim resistance has been
trimethoprim 18571 inherent resistance to trimethoprim; though recently, the methodology regarding the media used – where trimethoprim resistance has been observed – has been implicated with changing the result [[23], [28]]. Durations
vancomycin 5313 scan revealing pulmonary edema and bilateral pleural effusions. The patient was started on empiric vancomycin and piperacillin-tazobactam antibiotic therapy. Despite hemodynamic stability at presentation, his cardiopulmonary
vancomycin 7502 diffusion revealed a penicillin susceptible strain with 0.12mcg/ml by ETEST (bioMerieux). Ceftriaxone and vancomycin susceptibilities were obtained via Kirby Bauer susceptibility testing and revealed intermediate 2mcg/ml
vancomycin 17142 Lactam/AG–Y[[9]]4343MIndwelling CatheterMvYβ Lactam/AG6wksYaβ Lactam/AG Beta-Lactam/Aminoglycoside, Van- vancomycin , BPH benign prostatic hyperplasia; ASD Atrial septal defect, TURP trans-urethral prostate biopsy, UTI
Select Disease Character Offset Disease Term Instance
abscess 681 tract pathology. Infections beyond the genitourinary tract are rare, though spondylodiscitis, perineal abscess es, lymphadenitis, bacteremia, meningitis, and endocarditis have been reported. Less than fifty cases
meningitis 719 genitourinary tract are rare, though spondylodiscitis, perineal abscesses, lymphadenitis, bacteremia, meningitis , and endocarditis have been reported. Less than fifty cases of A. urinae infective endocarditis (IE)
septic shock 9300 etiologies. Fever, malaise, dyspnea (most often due to valvular dysfunction with ensuing pulmonary edema) and septic shock were common clinical manifestations of disease [[5], [9]]. The patient discussed above presented predominantly

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