Cytomegalovirus-related uncontrolled glaucoma in an immunocompetent patient: a case report and systematic review

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infectious disease 1 infectiousdiseases
ganciclovir 11 infectiousdiseasesdrugs

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ganciclovir 1704 pressure should be considered for CMV infection. We found that concurrent use of systemic and topical ganciclovir in a short period could reduce ocular CMV significantly, while ocular hypertension recurred. The antiviral
ganciclovir 5798 was positive (1800 copies/ml). Then the patient was treated with 2-week systemic antiviral therapy ( ganciclovir 5 mg/kg twice a day intravenously for a week, followed by once a day for another week), topical 0.15%
ganciclovir 5913 5 mg/kg twice a day intravenously for a week, followed by once a day for another week), topical 0.15% ganciclovir gel four times daily, 1% prednisolone acetate eye drops (Pred Forte) four times daily and local anti-glaucoma
ganciclovir 6864 genciclovir gel and glaucoma medications. In addition, systemic therapies were administered for anti-virus ( ganciclovir 5 mg/kg twice a day intravenously), anti-inflammatory (vein injection of methylprednisolone 80 mg
ganciclovir 9663 The common management focused on anti-virus and control elevated IOP [[3], [5], [6]]. Topical use of ganciclovir gel is well responded with minimal side effect and economized in CMV infections. But the ocular hypertension
ganciclovir 9851 infections. But the ocular hypertension with inflammation often recurred frequently. Various modalities of ganciclovir (or its prodrug valganciclovir) including oral application and intravitreal implantation/injection were
ganciclovir 9882 hypertension with inflammation often recurred frequently. Various modalities of ganciclovir (or its prodrug val ganciclovir ) including oral application and intravitreal implantation/injection were used [[5]–[9]]. Most studies
ganciclovir 10260 high regardless of treatment regimen [[6], [17]]. It was anticipated that antiviral medicines like ganciclovir are virostatic. It could reduce viral replication but could not eradicate it [[3], [6], [16], [18]].
ganciclovir 10614 reasons for the relapse of CMV induced hypertensive AU. In our case, after 14 days systemic using of ganciclovir combined with topical ganciclovir gel four times a day consistently, the CMV DNA copies from the aqueous
ganciclovir 10648 induced hypertensive AU. In our case, after 14 days systemic using of ganciclovir combined with topical ganciclovir gel four times a day consistently, the CMV DNA copies from the aqueous humor was much lower than that
ganciclovir 12764 infected case with repeatly elevated IOP and found out that concurrent use of systemic and topical ganciclovir in a short duration could reduce ocular CMV effectively. In view of the IOP increased with spikes may
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infectious disease 5647 infection antibodies in serum were also tested. Results showed serum IgG for CMV but no IgM, HIV and other infectious disease s. The CMV-DNA in aqueous sample was positive (1800 copies/ml). Then the patient was treated with 2-week

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