VEGF Upregulation in Viral Infections and Its Possible Therapeutic Implications.

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Annotation Summary

Term Occurence Count Dictionary
herpes simplex 1 infectiousdiseases
infectious mononucleosis 1 infectiousdiseases
ribavirin 1 infectiousdiseasesdrugs
cowpox 1 infectiousdiseases
dengue hemorrhagic fever 1 infectiousdiseases
hepatitis B 1 infectiousdiseases

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Select Drug Character Offset Drug Term Instance
ribavirin 28825 the symptoms in Hantavirus Pulmonary Syndrome (HPS) makes antiviral treatment such as interferon and ribavirin ineffective against the disease [[140],[141]]. Therefore, treatment strategies stabilizing endothelial
Select Disease Character Offset Disease Term Instance
cowpox 25173 were found also to express VEGF homolog such as the Bovine papular stomatitis virus (BPSV) and Pseudo cowpox (PCPV), which may also infect human [[123],[124]]. A VEGF homolog was also detected in the Parapoxviruses
dengue hemorrhagic fever 21006 disease called Dengue fever (DF). However, the disease may develop into severe complications called dengue hemorrhagic fever (DHF), which is characterized by increased capillary permeability and plasma leakage [[95]]. Continuous
hepatitis B 17467 this expression was found to be positively correlated with microvessel density (MVD) [[76],[77]].The hepatitis B viral protein x (HBx) is the key inducer of VEGF expression in HBV-related HCC. VEGF transcription was
herpes simplex 841 Kaposi’s sarcoma herpesvirus (KSHV) and Epstein-Barr virus (EBV) and non-oncogenic viruses such as herpes simplex virus (HSV-1) and dengue virus, which lack their own angiogenic factors, rely on the recruitment of
infectious mononucleosis 4863 infects the majority of the human population. EBV infection has been implicated in many diseases such as infectious mononucleosis after primary infection and neoplasia including lymphoproliferative disorders and lymphomas such as

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