Acute acalculous cholecystitis in children

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Term Occurence Count Dictionary
ampicillin 1 infectiousdiseasesdrugs
cefotaxime 2 infectiousdiseasesdrugs
diarrhea 4 infectiousdiseases
leptospirosis 1 infectiousdiseases
ofloxacin 1 infectiousdiseasesdrugs
septic shock 4 infectiousdiseases
hepatitis A 3 infectiousdiseases
infectious disease 3 infectiousdiseases
quinine 3 infectiousdiseasesdrugs
typhoid fever 2 infectiousdiseases
ascariasis 1 infectiousdiseases
dexamethasone 1 infectiousdiseasesdrugs
gentamicin 5 infectiousdiseasesdrugs
metronidazole 10 infectiousdiseasesdrugs
pneumonia 1 infectiousdiseases

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
ampicillin 21898 United States)4-M-Cotrimoxazole rifampinDiagnosis through blood culture (initial antibiotic therapy with ampicillin , metronidazole and gentamicin)Croteau et al[[75]] (N/A, 2001, United States)2-MLaparoscopic cholecystectomySecond-generation
cefotaxime 23244 Greece)13-F-Cefotaxime, tobramicin, metronidazoleShin et al[[14]] (Nephrotic syndrome, 2007, South Korea)5-M-Ampicillin, cefotaxime Deflazacort 60 mg/m2Gora-Gebkaet al[[39]] (EBV + CMV and EBV, 2008, Poland)9-F, 4-F-CefotaximeBouyahia
cefotaxime 25870 PEG-asparaginase)Aguilera-Alonso et al[[60]] (Plasmodium falciparum, 2018, Spain/Equatorial Guinea)5-F-Clindamycin, cefotaxime , metronidazoleIntravenous quinine as soon as definitive diagnosis was achievedIsmaili-Jaha et al[[59]]
dexamethasone 25712 (ALL-T, 2017, United Kingdom)12-M-Piperacillin-tazobactam, metronidazoleNeutropenia during chemotherapy ( dexamethasone , daunorubicin, vincristine, PEG-asparaginase)Aguilera-Alonso et al[[60]] (Plasmodium falciparum, 2018,
gentamicin 21928 rifampinDiagnosis through blood culture (initial antibiotic therapy with ampicillin, metronidazole and gentamicin )Croteau et al[[75]] (N/A, 2001, United States)2-MLaparoscopic cholecystectomySecond-generation cephalosporinRemoval
gentamicin 23406 and EBV, 2008, Poland)9-F, 4-F-CefotaximeBouyahia et al[[41]] (HAV, 2008, Tunisia)14-M-Cefotaxime, gentamicin Suresh et al[[43]] (HAV, 2009, India)2-F--Souza et al[[44]] (HAV, 2009, Brazil)16-M--Mendonca et al[[15]],
gentamicin 23958 complicated (perforated) AACArroud et al[[45]] (HAV, 2011, Morocco)11-M-Amoxicillin-clavulanic acid, gentamicin Herek et al[[46]] (HAV, 2011, Turkey)9-M--Pal K[[24]], (Type I Diabetes mellitus, 2011, Saudi Arabia)11-MLaparoscopic
gentamicin 24354 al[[47]] (HAV, 2012, India)12-F--Newcombe et al[[48]] (C. Burnetii, 2013, Australia)9-M-Ampicillin, gentamicin , metronidazoleAAC as probable complication of infection-associated anti-phospholipid syndromeShihabuddin
gentamicin 31801 in Table 3. Most used antibiotics were a variable combination of a third generation cephalosporin, gentamicin and metronidazole[[86],[87]]. Unfortunately, specific guidelines for pediatric cholecystitis are not
metronidazole 21910 States)4-M-Cotrimoxazole rifampinDiagnosis through blood culture (initial antibiotic therapy with ampicillin, metronidazole and gentamicin)Croteau et al[[75]] (N/A, 2001, United States)2-MLaparoscopic cholecystectomySecond-generation
metronidazole 22348 al[[31]] (S. Aureus, 2003, United States)12-MLaparotomic cholecystectomyAmpicillin/sulbactam Ceftriaxone, metronidazole AAC developed for bacteriemia during osteomyelitis.Saha et al[[33]] (P. Falciparum, 2005, India)7-F-CeftriaxoneIntravenous
metronidazole 22620 diagnosis was achievedBasiratnia et al[[13]] (SLE, 2006, Iran)10-MLaparotomic cholecystectomyCeftriaxone, metronidazole High-dose prednisolone for 3 d. Surgical approach due to poor response (not specified)Kuttiat et al[[35]]
metronidazole 23159 triamphenicolHalofantrin was started upon diagnosisPrassouli et al[[38]] (EBV, 2007, Greece)13-F-Cefotaxime, tobramicin, metronidazole Shin et al[[14]] (Nephrotic syndrome, 2007, South Korea)5-M-Ampicillin, cefotaximeDeflazacort 60 mg/m2Gora-Gebkaet
metronidazole 24366 (HAV, 2012, India)12-F--Newcombe et al[[48]] (C. Burnetii, 2013, Australia)9-M-Ampicillin, gentamicin, metronidazole AAC as probable complication of infection-associated anti-phospholipid syndromeShihabuddin et al[[22]]
metronidazole 25310 evidence of other eosinophilic diseaseMajdalani et al[[57]] (EBV, 2016, Lebanon)16-F-Ciprofloxacin, metronidazole Rodà et al[[79]] (EBV, 2016, Spain)2-M-CeftriaxoneConcomitant nephrotic syndrome and EBV infectionÖzkaya
metronidazole 25666 2016, Portugal)3-M--Naselli et al[[23]] (ALL-T, 2017, United Kingdom)12-M-Piperacillin-tazobactam, metronidazole Neutropenia during chemotherapy (dexamethasone, daunorubicin, vincristine, PEG-asparaginase)Aguilera-Alonso
metronidazole 25882 PEG-asparaginase)Aguilera-Alonso et al[[60]] (Plasmodium falciparum, 2018, Spain/Equatorial Guinea)5-F-Clindamycin, cefotaxime, metronidazole Intravenous quinine as soon as definitive diagnosis was achievedIsmaili-Jaha et al[[59]] (Ascaris lumbricoides,
metronidazole 26156 (not specified)MebendazoleNg et al[[80]] (N/A, concomitant pneumonia, 2018, Australia)7-M-Ceftriaxone, metronidazole AAC: Acute acalculous cholecystitis; CMV: Cytomegalovirus; EBV: Epstein-Barr virus; HAV: Hepatitis A
metronidazole 31816 Most used antibiotics were a variable combination of a third generation cephalosporin, gentamicin and metronidazole [[86],[87]]. Unfortunately, specific guidelines for pediatric cholecystitis are not available, and controlled
ofloxacin 25299 cholecysitis without evidence of other eosinophilic diseaseMajdalani et al[[57]] (EBV, 2016, Lebanon)16-F-Cipr ofloxacin , metronidazoleRodà et al[[79]] (EBV, 2016, Spain)2-M-CeftriaxoneConcomitant nephrotic syndrome and
quinine 22484 bacteriemia during osteomyelitis.Saha et al[[33]] (P. Falciparum, 2005, India)7-F-CeftriaxoneIntravenous quinine as soon as definitive diagnosis was achievedBasiratnia et al[[13]] (SLE, 2006, Iran)10-MLaparotomic
quinine 22811 specified)Kuttiat et al[[35]] (P. falciparum and P. Vivax, 2007, India)8-M 9-M-CeftriaxoneIntravenous quinine as soon as definitive diagnosis was achievedLagona et al[[36]] (EBV, 2007, Greece)4-F--Only supportive
quinine 25907 (Plasmodium falciparum, 2018, Spain/Equatorial Guinea)5-F-Clindamycin, cefotaxime, metronidazoleIntravenous quinine as soon as definitive diagnosis was achievedIsmaili-Jaha et al[[59]] (Ascaris lumbricoides, Albania,
Select Disease Character Offset Disease Term Instance
ascariasis 12347 typhoid fever and leptospirosis[[6]]. AAC can be one of the clinical manifestations of hepatobiliary ascariasis , characterized by the passage of worms from the duodenum to the biliary tract, leading to bile flow
diarrhea 13810 20017MHAVAbdominal pain, fever, jaundiceLo et al[[30]], 20025MSalmonella group DAbdominal pain, fever, vomiting, diarrhea Batra et al[[31]], 200312MS. aureusRUQ pain, fever, jaundice, maculopapular rashGarel et al[[32]], 20034MSalmonella
diarrhea 13971 jaundice, maculopapular rashGarel et al[[32]], 20034MSalmonella spp.Abdominal pain, fever, vomiting, diarrhea Saha et al[[33]], 20057FP. falciparumRUQ pain, feverAxelrod et al[[44]], 20073FS. typhiAbdominal pain,
diarrhea 14341 jaundice, vomiting, anorexiaAnthoine-Milhomme et al[[37]], 20077FPlasmodium spp.Abdominal pain, fever, diarrhea , jaundicePrassouli et al[[38]], 200713FEBVAbdominal pain, fever, vomiting, jaundiceGora-Gebka et al[[39]],
diarrhea 15954 maculo-papular skin rashIsmaili-Jaha et al[[59]], 20181, 2, 4, 10F, F, F, MAscaris lumbricoidesMainly fever, diarrhea , vomitingAguilera-Alonso et al[[60]], 20185FP. falciparumAbdominal pain, fever, jaundiceCMV: Cytomegalovirus;
hepatitis A 1089 after 2000 described children developing AAC during viral illnesses (such as Epstein-Barr virus and hepatitis A virus infections). Moreover, some pediatric cases have been associated with several underlying chronic
hepatitis A 1932 have described children developing AAC during viral illnesses, in particular, Epstein-Barr virus and hepatitis A virus infections. Moreover, some pediatric cases have been associated with non-infectious disorders,
hepatitis A 16245 virus; RUQ: Right upper quadrant.Among AAC cases due to viral infections, many have been associated with hepatitis A virus (HAV) and Epstein-Barr virus (EBV); however, only a minority of infected children develop AAC,
infectious disease 878 in critically ill or post-surgical patients, most pediatric cases have been observed during several infectious disease s. In addition to cases caused by bacterial and parasitic infections, most pediatric reports after 2000
infectious disease 1729 post-surgical patients, as it often occurs in adults, but most pediatric cases are actually caused by infectious disease s. In addition to bacterial and parasitic infections, most recent pediatric reports have described children
infectious disease 6998 patients suffering from vasculitis or previously healthy children developing ACC during a concomitant infectious disease [[9],[10]].EPIDEMIOLOGY AND RISK FACTORSGallbladder disease is a relatively rare condition in children.
leptospirosis 12264 of infectious AAC referred to intestinal parasites (e.g., Ascaris lumbricoides), typhoid fever and leptospirosis [[6]]. AAC can be one of the clinical manifestations of hepatobiliary ascariasis, characterized by the
pneumonia 26112 Albania, 2018)1-F, 2-F, 4-F, 10-M-Antibiotics (not specified)MebendazoleNg et al[[80]] (N/A, concomitant pneumonia , 2018, Australia)7-M-Ceftriaxone, metronidazoleAAC: Acute acalculous cholecystitis; CMV: Cytomegalovirus;
septic shock 6577 diseases (cardiac infarction - treated with emergency coronary bypass -, staphylococcal septicemia, septic shock and hypovolemic shock), which highlighted the fact that ischemic factors and/or tissue hypoxia are the
septic shock 28036 hemoglobin value, presence of pericholecystic fluid/high sonographic score, hypofibrinogenemia and septic shock ) as being predictive of poor outcome. However, all of their patients were treated non-operatively, including
septic shock 28914 cholecystectomy. Interestingly, no patients were admitted to the intensive care unit or presented with septic shock , but the indication for shifting from the conservative to the surgical approach was not specified. On
septic shock 29661 hemodynamically unstable, three had multi-organ system failure, three developed renal failure and one was in septic shock . No patient developed procedure-related complications, but four patients died because of concomitant
typhoid fever 12246 2000, most reports of infectious AAC referred to intestinal parasites (e.g., Ascaris lumbricoides), typhoid fever and leptospirosis[[6]]. AAC can be one of the clinical manifestations of hepatobiliary ascariasis, characterized
typhoid fever 12589 fever is a systemic infection caused by some Salmonella species, in particular Salmonella typhi. AAC in typhoid fever is usually a secondary complication depending on bacterial strain virulence or its resistance to treatment,

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