The Effectiveness of Antiviral Treatments for Patients with HBeAg-Positive Chronic Hepatitis B: A Bayesian Network Analysis

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Annotation Summary

Term Occurence Count Dictionary
hepatitis A 1 infectiousdiseases
hepatitis B 3 infectiousdiseases
lamivudine 2 infectiousdiseasesdrugs
tenofovir 2 infectiousdiseasesdrugs

Graph of close proximity drug and disease terms (within 200 characters).

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Select Drug Character Offset Drug Term Instance
lamivudine 3535 of the following therapies (such as monotherapy, combination, add-on, or switching): placebo (PLA), lamivudine (LAM), adefovir (ADV), entecavir (ETV), lamivudine (LdT), tenofovir (TDF), and PEG IFN. The following
lamivudine 3586 combination, add-on, or switching): placebo (PLA), lamivudine (LAM), adefovir (ADV), entecavir (ETV), lamivudine (LdT), tenofovir (TDF), and PEG IFN. The following exclusion criteria were excluded in this study: (1)
tenofovir 3604 or switching): placebo (PLA), lamivudine (LAM), adefovir (ADV), entecavir (ETV), lamivudine (LdT), tenofovir (TDF), and PEG IFN. The following exclusion criteria were excluded in this study: (1) non-RCTs; (2)
tenofovir 17570 nucleoside/nucleotide analogs; PEG IFN, PEG IFNylated interferon; PLA, placebo; ETV, entecavir; TDF, tenofovir ; wk, weekTable 2The results of direct analysis estimates of efficacy (hazard ratio).TreatmentStudy ALT
Select Disease Character Offset Disease Term Instance
hepatitis A 3731 IFN. The following exclusion criteria were excluded in this study: (1) non-RCTs; (2) coinfection with hepatitis A , C, D, or E, cytomegalovirus, or HIV; (3) patients who were children; (4) patients who were not with
hepatitis B 2194 infection has greatly increased [[2]]. This highlights the need for effective treatments for chronic hepatitis B (CHB).Currently, two sets of treatments are available for the treatment of HBV infection, which are
hepatitis B 4277 original review conducted up to 15th January 2018. The search was conducted using the key words ‘HBV or hepatitis B or CHB' and ‘IFN or interferon' and ‘random∗'. Potentially relevant papers were reviewed by two
hepatitis B 12955 long-term NAs have a greater effect on HBV intrahepatic cccDNA decline. As reported, low quantitative hepatitis B surface antigen (qHBsAg) and HBV DNA were strong predictive stopping rule in HBV patients treated with

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