Pasteurella multocida line infection: a case report and review of literature

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Annotation Summary

Term Occurence Count Dictionary
Ceftazidime 1 infectiousdiseasesdrugs
aztreonam 1 infectiousdiseasesdrugs
erythromycin 1 infectiousdiseasesdrugs
tetracycline 2 infectiousdiseasesdrugs
vancomycin 1 infectiousdiseasesdrugs
amoxicillin 1 infectiousdiseasesdrugs
ampicillin 3 infectiousdiseasesdrugs
diarrhea 1 infectiousdiseases
epinephrine 2 infectiousdiseasesdrugs
gentamicin 4 infectiousdiseasesdrugs
meningitis 1 infectiousdiseases
moxifloxacin 2 infectiousdiseasesdrugs
penicillin G 1 infectiousdiseasesdrugs
septic shock 1 infectiousdiseases
gram-negative bacterial infection 1 infectiousdiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

Review

Having read the paper, please pick a pair of statements from the paper to indicate that a drug and disease are related.

Select Drug Character Offset Drug Term Instance
Ceftazidime 6904 during the inpatient period (Vancomycin (Van), Aztreonam (Atm), Gentamicin (Gen), Moxifloxacin (MXF), Ceftazidime (Caz))Further history from the patient revealed that the patient’s kittens played with his tunnelled
amoxicillin 8617 treatment is recommended with β–lactam/β–lactamase combinations such as ampicillin/sulbactam or amoxicillin /clavulanic [[5]]. Alternatives that have shown good activity against P multocida include second and
ampicillin 8593 reported and empiric treatment is recommended with β–lactam/β–lactamase combinations such as ampicillin /sulbactam or amoxicillin/clavulanic [[5]]. Alternatives that have shown good activity against P multocida
ampicillin 10375 course of intraperitoneal antibiotics was most likely adequate. They recommended use of penicillin or ampicillin -based regimens for non-β-lactamase producing isolates. Alternatives included third generation cephalosporins,
ampicillin 11481 treatment failure of intraperitoneal aminoglycosides, the authors recommend catheter lock with either ampicillin or a cephalosporin such as ceftazidime depending on isolate sensitivities. In the case of purulent line
aztreonam 5448 atrium.The patient was admitted to the intensive care unit and placed empirically on vancomycin and aztreonam due to his penicillin allergy. A single dose of gentamicin 3 mg/kg was administered after gram-negative
epinephrine 5788 arterial line placement. His midodrine was increased to 10 mg three times daily and he was started on nor epinephrine via peripheral intravenous catheter. His haemodynamic parameters, fever chart and antibiotics administered
epinephrine 6035 12 h, the patient was alert and oriented, his hands and feet were warm and lactate 0.5 mmol/L. Nor epinephrine was discontinued. Initial blood cultures drawn in the emergency department were reported as positive
erythromycin 6401 laser desorption/ionization –time of flight (MALDI-TOF) revealing Pasteurella multocida sensitive to erythromycin (minimum inhibitory concentration (MIC) 4mcg/mL), moxifloxacin (MIC 0.023 mcg/mL), penicillin G (MIC
gentamicin 1371 catheter and was thereafter treated for a total of 2 weeks with intravenous ceftazidime post-dialysis and gentamicin line-locks without recurrence of infection.ConclusionsPasteurella Multocida bacteremia in the presence
gentamicin 4621 jugular catheter. He denied smoking, alcohol or drug use. Medications prior to admission included topical gentamicin ointment around the catheter entry site and he reported previously developing an itchy rash with penicillins.The
gentamicin 5506 and placed empirically on vancomycin and aztreonam due to his penicillin allergy. A single dose of gentamicin 3 mg/kg was administered after gram-negative rods were identified in the blood cultures and cautious
gentamicin 7266 after susceptibilities were known then ultimately ceftazidime 1 g after dialysis 5 times weekly with gentamicin catheter locks. The choice of ceftazidime was based on ease of dosing with dialysis. He was discharged
moxifloxacin 6464 revealing Pasteurella multocida sensitive to erythromycin (minimum inhibitory concentration (MIC) 4mcg/mL), moxifloxacin (MIC 0.023 mcg/mL), penicillin G (MIC 0.064 mcg/mL) and tetracycline (0.75 mcg/mL). Peripheral and central
moxifloxacin 7151 the small puncture in one of the ports prior to admission. He was initially switched to intravenous moxifloxacin after susceptibilities were known then ultimately ceftazidime 1 g after dialysis 5 times weekly with
penicillin G 6497 to erythromycin (minimum inhibitory concentration (MIC) 4mcg/mL), moxifloxacin (MIC 0.023 mcg/mL), penicillin G (MIC 0.064 mcg/mL) and tetracycline (0.75 mcg/mL). Peripheral and central venous catheter blood cultures
tetracycline 6533 concentration (MIC) 4mcg/mL), moxifloxacin (MIC 0.023 mcg/mL), penicillin G (MIC 0.064 mcg/mL) and tetracycline (0.75 mcg/mL). Peripheral and central venous catheter blood cultures drawn 12 h after admission were
tetracycline 8762 that have shown good activity against P multocida include second and third generation cephalosporins, tetracycline s, co-trimoxazole and fluoroquinolones.Infection of prosthetic material with P. multocida following animal
vancomycin 5433 over the right atrium.The patient was admitted to the intensive care unit and placed empirically on vancomycin and aztreonam due to his penicillin allergy. A single dose of gentamicin 3 mg/kg was administered after
Select Disease Character Offset Disease Term Instance
diarrhea 3306 haemodialysis presented to the emergency department with 12 h of fatigue, several episodes of watery diarrhea and nausea but no emesis. He reported chills, diaphoresis, light-headedness and fever as well as tenderness
gram-negative bacterial infection 2752 is unknown. Existing guidelines published by the Infectious Diseases Society of America suggest that gram-negative bacterial infection s of central venous catheters may be treated with 10–14 days of targeted intravenous therapy though
meningitis 8055 necrotising fasciitis, septic arthritis, osteomyelitis and less commonly septic shock, endocarditis and meningitis . The bacteria have several potential virulence factors including capsular lipopolysaccharide, a cytotoxin,
septic shock 8024 of complications including necrotising fasciitis, septic arthritis, osteomyelitis and less commonly septic shock , endocarditis and meningitis. The bacteria have several potential virulence factors including capsular

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