Lactose Intolerance, Dairy Avoidance, and Treatment Options

Existing Reviews

Please note, new claims can take a short while to show up.

No claims yet.

Annotation Summary

Term Occurence Count Dictionary
ergocalciferol 1 endocrinologydiseasesdrugs
galactosemia 2 endocrinologydiseases
hypercalcemia 2 endocrinologydiseases
lactose intolerance 26 endocrinologydiseases
Insulin 1 endocrinologydiseasesdrugs
cholecalciferol 1 endocrinologydiseasesdrugs
metabolic syndrome 4 endocrinologydiseases
obesity 7 endocrinologydiseases
osteoporosis 10 endocrinologydiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

Review

Having read the paper, please pick a pair of statements from the paper to indicate that a drug and disease are related.

Select Drug Character Offset Drug Term Instance
Insulin 46460 qualifying studies concluded that the impact is likely through elevation of IGF-1 with dairy intake [[171]]. Insulin -like growth factors are implicated in various disease states, including neoplasia [[172]].The epidemiology
cholecalciferol 53930 (ergocalciferol) of plant origin and there is scientific evidence pointing to the superior bioavailability of D3 ( cholecalciferol ) with which dairy milk is fortified [[187]].Plant-based dairy substitutes, when consumed as main beverages,
ergocalciferol 53817 fortification is not fully known [[184]]. Vitamin D added to plant-based beverages is in the form of D2 ( ergocalciferol ) of plant origin and there is scientific evidence pointing to the superior bioavailability of D3 (cholecalciferol)
Select Disease Character Offset Disease Term Instance
galactosemia 7411 [[14]]. Alterations in Leloir pathway enzymes lead to rare genetic metabolic diseases classified as galactosemia s [[15]]. The other major substrate of LPH situated on a separate site is the flavonoid phlorizin which
galactosemia 42814 lead to neoplastic changes in the ovarian epithelium such as that observed in severe cases of Type 1 galactosemia [[150],[151]], but this was not confirmed in normal women [[152]]. Nevertheless, the observation of
hypercalcemia 11989 rapidly develop with the beginning of breast feeding. Often there is severe diarrhea, acidosis, and hypercalcemia [[38]]. The therapy is to avoid all forms of milk. In premature neonates intestinal lactase may not
hypercalcemia 68578 initially in Finland, now a few cases elsewhere also. It is associated with severe diarrhea acidosis and hypercalcemia .Developmental Lactase deficiency [[39],[40]]Premature neonates usually have insufficient intestinal
lactose intolerance 1018 functional gastrointestinal disorders. Partly because lactose maldigestion is often interpreted as lactose intolerance (symptoms), focus of therapy for these symptoms starts with lactose restriction. However, withholding
lactose intolerance 1398 completely successful at this time. This narrative article reviews the complexities of the perception of lactose intolerance , its epidemiology, and pathogenesis. Treatments are discussed, including the inappropriateness of dairy
lactose intolerance 2013 both the scientific community and the public. When one uses the popular web search engine Google for lactose intolerance , more than 8 × 106 sites appear in seconds. The discovery that lactose digestion capability is a genetic
lactose intolerance 4660 formate). These metabolic products, and their rate of production, can contribute to symptoms of LI ( lactose intolerance ) [[6]].Lactase distributions are also related to the geographic patterns of some diseases [[3],[7]].
lactose intolerance 5175 distributions will likely change as population migrations shift.This review will outline “classical” lactose intolerance and differentiate other nutrients which cause similar symptoms. The article will review treatment options
lactose intolerance 14097 revealing adult hypolactasia. These causes are outlined in Table 1.4. Lactose IntoleranceThe classical term lactose intolerance (LI) has been applied to the development of gastrointestinal symptoms (of gas, bloat, abdominal cramps,
lactose intolerance 20778 This however is not the case.When patients blame LI for symptoms an important question when evaluating lactose intolerance is whether patients’ association of gastrointestinal symptoms with ingestion of lactose is a reliable
lactose intolerance 20951 gastrointestinal symptoms with ingestion of lactose is a reliable predictor of lactose maldigestion. Self-reported lactose intolerance refers to the belief that the person is likely to suffer gastrointestinal symptoms after consuming lactose.
lactose intolerance 21381 for abdominal symptoms reported minimal to zero differences between the groups [[66]].Self-reported lactose intolerance is an unreliable diagnostic tool for lactose maldigestion. In a systematic review of 26 studies, evaluating
lactose intolerance 22306 [[69],[70]]. Others have also attributed mood changes which accompanied carbohydrate ingestion, especially lactose intolerance [[71]].In accordance with SRLI a placebo effect and a nocebo effect (the belief that what is consumed
lactose intolerance 23031 negative results was eliminated [[74]].These analyses suggest that the population-reported notion of lactose intolerance as a cause of multiple symptoms does not predict maldigestion of lactose. It is entirely possible then,
lactose intolerance 23630 these functional disorders the irritable bowel syndrome (IBS) has the closest semblance and may mimic lactose intolerance . The cause(s) of IBS, to date, is not based on defined pathology and is thought to be related to interactions
lactose intolerance 27172 to cow’s milk protein (whey and casein) is largely limited to children and is very different from lactose intolerance [[92]]. The allergens are thought to be to αs1-, αs2-, β-, and κ-casein and α- and β-lactoglobulin
lactose intolerance 28222 is to eliminate dairy foods from diet. However, the conclusion of an NIH single-topic conference on lactose intolerance concluded that the main health impact of this condition is the withholding of milk and dairy products
lactose intolerance 50078 Availability and the relative low cost of dairy products makes their consumption more convenient. While lactose intolerance is a real entity, in response to excess lactose intake, the general perception of lactose intolerance
lactose intolerance 50180 lactose intolerance is a real entity, in response to excess lactose intake, the general perception of lactose intolerance is made up of a number of conditions which present with similar symptomology. As such, treatments for
lactose intolerance 50553 options.6.1. Lactose-Free and Lactose-Reduced ProductsThe avoidance of all dairy products in patients with lactose intolerance is no longer recommended. Most people with lactose intolerance can tolerate up to 12–15 grams of lactose
lactose intolerance 50616 all dairy products in patients with lactose intolerance is no longer recommended. Most people with lactose intolerance can tolerate up to 12–15 grams of lactose per day. Strategies to increase tolerance of lactose containing
lactose intolerance 50889 adequacy, avoiding deficiencies and improving symptoms [[182]] are summarized in Table 4. People with lactose intolerance should be encouraged to restrict rather than avoid lactose with the goal of including some dairy foods
lactose intolerance 56526 outcome. 6.4. Adaptation and Prebiotics for Treatment of Lactose IntoleranceThe notion of adaptation to lactose intolerance dates to the mid-20th century when milk powder was provided to some developing countries [[193],[194]].
lactose intolerance 62054 role is unclear even after appropriate tests for maldigestion of lactose. Most patients have heard of lactose intolerance and often they have restricted their intake without clear benefit. These patients may have other food
lactose intolerance 62273 food intolerances or react to nutrients different from lactose in dairy.As outlined above symptoms of lactose intolerance can merge with several other causes. Milk intolerance due to fats, A1 casein, or actual milk protein
lactose intolerance 66087 therefore, is not yet clear, but do serve as other possible therapeutic options.8. SummaryThe term lactose intolerance currently encompasses a more complex meaning than in the past. The continued concept that lactose maldigestion
lactose intolerance 66235 complex meaning than in the past. The continued concept that lactose maldigestion is equivalent to lactose intolerance confuses understanding of the proper place of lactose specific management in lay persons’ and perhaps
lactose intolerance 66586 reflect every day consumption of lactose, when combined with other foods. The symptom complexities of lactose intolerance could be modified by other food intolerances and the presence of functional gastrointestinal disorders.
lactose intolerance 72961 noted in the text.nutrients-10-01994-t004_Table 4Table 4Recommendations for management of diagnosed lactose intolerance .1. Gradual introduction of cow milkStart with 30–60 mL per day and gradually increase to a maximum
metabolic syndrome 33355 adolescents than adults.5.2. Cardiometabolic SyndromesThe potential benefits of dairy foods against cardio metabolic syndrome s (these syndromes collectively refer to dyslipidemia (met S, high cholesterol or triglycerides both
metabolic syndrome 34985 relationship while regular high fat dairy yogurt and milk showed no association [[116]]. Analyses with metabolic syndrome were based on limited studies, but total dairy and milk consumption did vary inversely. Other products
metabolic syndrome 36398 that low-fat dairy and yogurt reduces risk for T2D. There is moderate-quality evidence that risk for metabolic syndrome is reduced by total dairy and milk, while total dairy and cheese reduce risk for T2D. In the case of
metabolic syndrome 72138 dairy foods, Lfat—low fat milk, Hfat—high fat milk, Ferment—refers to fermented dairy. MetS— metabolic syndrome , CAD—coronary artery disease, CVD—cardiovascular disease, HTN—hypertension, T2D—type 2 diabetes,
obesity 33686 cardiovascular (CVD) and coronary artery disease (CAD), stroke, and type 2 diabetes (T2D), as well as obesity , remain controversial. Part of the confounding effects may have been related to attempts to link individual
obesity 34599 determined with each disease. These components were evaluated with the diseases listed above (except obesity ). Evaluating CVD, the various forms of dairy had a neutral effect. Similarly, the relationships between
obesity 38227 using Mendelian randomization, however, failed to show any impact [[130]].The association of dairy with obesity has also run a contradictory course. Systematic reviews and meta-analyses of the effects of dairy on
obesity 38785 the Mendelian Randomization of Dairy Consumption Working Group concluded that dairy products promote obesity . There is a possible counter argument to this conclusion in that the TT lactase (C/T-13910) genotype
obesity 48340 to support a modest benefit for hypertension and type 2 diabetes. Weight reduction and prevention of obesity may be facilitated by dairy foods in the short-term and in conjunction with energy restriction. However,
obesity 48599 studies are evaluated by the method of genetic Mendelian randomization. Evaluation of hypertension, obesity and type 2 diabetes in these studies fail to support beneficial effects. The reasons for discrepancies
obesity 71682 included the genetic polymorphism as an instrumental variable did not show that dairy intake reduced obesity , hypertension, or type 2 diabetes [[125],[126],[130],[132]]. However, a study evaluating risk of milk
osteoporosis 28907 bone dynamics which is constantly remodeled throughout life (development, maturation, maintenance, and osteoporosis ). Bone turnover is increased with aging and in a number of pathological states, such as osteoporosis.
osteoporosis 29008 osteoporosis). Bone turnover is increased with aging and in a number of pathological states, such as osteoporosis . The increased bone turnover leads to deterioration of bone microarchitecture which then, independently
osteoporosis 30844 question of whether lactase non-persistence status (known for reduced dairy consumption) may predispose to osteoporosis . The basis for the query is that LNP populations consume less dairy than LP populations [[3],[4],[5],[102]].
osteoporosis 31844 intake/day [[106]].The ongoing controversy is whether LNP and low dairy consumption lead to higher rates of osteoporosis and fractures. There are reports that LNP persons consume less milk calcium which leads to reduced bone
osteoporosis 32310 symptoms [[111]]. On epidemiological grounds there is little information on national prevalence rates of osteoporosis . A review by Wade et al. found the highest rate for women in Japan (>73% LNP rate) and the lowest rates
osteoporosis 32628 Hernlund et al., from the European Union, found that Germany (16% LNP) had the highest prevalence of osteoporosis and Italy (72% LNP) had the second highest. Moreover, a compilation of fractures showed the highest
osteoporosis 32908 reports lead to two observations. There may be a weak correlation between national LNP rates [[33]] and osteoporosis rates, however, methods of osteoporosis definitions vary. Second there is a discord between osteoporosis
osteoporosis 32948 be a weak correlation between national LNP rates [[33]] and osteoporosis rates, however, methods of osteoporosis definitions vary. Second there is a discord between osteoporosis rates and national fracture prevalence.
osteoporosis 33013 osteoporosis rates, however, methods of osteoporosis definitions vary. Second there is a discord between osteoporosis rates and national fracture prevalence. The reasons for these discrepancies are not clear. Nevertheless,
osteoporosis 71194 case of bone calcium from dairy products is the most consistent in western societies. However, bone osteoporosis and fractures are controversial.DiseaseTDFMilkLfatHfatLactoseCheeseYogurtFermentCalciumBone----? -----MetS-CADnnnnnn-?

You must be authorized to submit a review.