Control of visceral leishmaniasis in latin america-a systematic review

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Annotation Summary

Term Occurence Count Dictionary
AIDS 1 infectiousdiseases
amphotericin b 1 infectiousdiseasesdrugs
cutaneous leishmaniasis 1 infectiousdiseases
infectious disease 2 infectiousdiseases
malaria 1 infectiousdiseases
paromomycin 1 infectiousdiseasesdrugs
permethrin 2 infectiousdiseasesdrugs
visceral leishmaniasis 13 infectiousdiseases

Graph of close proximity drug and disease terms (within 200 characters).

Note: If this graph is empty, then there are no terms that meet the proximity constraint.

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Select Drug Character Offset Drug Term Instance
amphotericin b 10543 following key-words were used: (visceral leishmaniasis OR kala azar OR L. chagasi OR L donovani) AND ( amphotericin b OR glucantime OR sodium stibogluconate OR miltefosine OR sitamaquine OR pentavalent antimonials OR paromomycin)
paromomycin 10657 OR glucantime OR sodium stibogluconate OR miltefosine OR sitamaquine OR pentavalent antimonials OR paromomycin ) AND “Americas” [MeSH]. For the LILACS search the key-words: leishmaniasis AND visceral AND treatment
permethrin 35019 symptomatic VL disease was 75% [104].Giffoni et al (2002) reported the effect of application of a 65% permethrin spot-on formulation on canine VL infection and sandfly abundance. A decrease of canine VL prevalence
permethrin 43909 low external validityBrazil 1999Two localities in the Corumba municipality, State of Mato Grosso65% permethrin spot-on three times monthly1 intervention locality vs 1 controlIntervention area: 150 dogs5 monthsCanine
Select Disease Character Offset Disease Term Instance
AIDS 19736 them?)How to improve clinician's awareness about the possibility of Leishmania co-infection in HIV/ AIDS cases?IV: Questions for researchWhat can be the contribution of novel (molecular) parasite detection
cutaneous leishmaniasis 20061 performance of antibody-assays in patients from areas with sympatric circulation of parasites causing cutaneous leishmaniasis ?Canine diagnosisSeventy-seven papers were retrieved from Medline/PubMed search and 11 of them were considered
infectious disease 16566 of 4 (bone marrow, IFAT, CIEP, Western blot).***OD : patients with other, potentially cross-reacting infectious disease s.****HEC: Healthy Endemic Controls.Phase 2: Case-Control design, laboratory based study on banked serum
infectious disease 23217 PCR positive.NEC: healthy dogs from non-endemic areas.OD: dogs with other, potentially cross-reacting infectious disease s.HEC: healthy dogs from endemic areas.Recently more “user-friendly” diagnostics as the DAT and a
malaria 38191 intervention should be explored further because it could bring an additional benefit in areas where malaria is also endemic [109].Costa et al (2007) reported a randomized community intervention trial to compare
visceral leishmaniasis 628 (epub): 1/2010AbstractBackgroundWhile three countries in South Asia decided to eliminate anthroponotic visceral leishmaniasis (VL) by 2015, its control in other regions seems fraught with difficulties. Is there a scope for more
visceral leishmaniasis 10013 Keywords and MESH Headings Used for Literature SearchesDiagnosis of human VL: For the PubMed search: ( visceral leishmaniasis OR kala-azar OR L.infantum OR L. chagasi OR L.donovani OR Leishmania infantum OR Leishmania chagasi
visceral leishmaniasis 10473 dipstick) were used.Treatment of human VL: For the PubMed search the following key-words were used: ( visceral leishmaniasis OR kala azar OR L. chagasi OR L donovani) AND (amphotericin b OR glucantime OR sodium stibogluconate
visceral leishmaniasis 10858 visceral AND treatment were used. For the Cochrane Central Register of Controlled Trials we used the term visceral leishmaniasis because the search with the key-words and MeSH terms used for the PubMed searching failed to retrieve
visceral leishmaniasis 11048 PubMed searching failed to retrieve any paper.Diagnosis of canine VL: For the PubMed search: (canine visceral leishmaniasis OR L.infantum OR L.chagasi OR L.donovani OR Leishmania infantum OR Leishmania chagasi OR Leishmania
visceral leishmaniasis 11481 AND diagnosis were used.Control of the animal reservoir and arthropod vector: for the PubMed search: ( visceral leishmaniasis OR Leishmania chagasi OR L chagasi OR Kala-azar OR Leishmania infantum) AND “Americas” [MeSH] AND
visceral leishmaniasis 11662 Leishmania infantum) AND “Americas” [MeSH] AND control. The LILACS search was performed using the term visceral leishmaniasis OR leishmaniose visceral OR leishmaniasis visceral because of the failure to retrieve any paper when
visceral leishmaniasis 13313 included: original studies evaluating the DAT or the rK39 immunochromatographic test (ICT); clinical visceral leishmaniasis diseases in humans as target condition; adequate reference classification; absolute numbers of true-positive,
visceral leishmaniasis 15623 diagnosis.10.1371/journal.pntd.0000584.t001Table 1Main characteristics of diagnostic accuracy studies reporting on tests for human visceral leishmaniasis in Latin America.CountryType of studyDiagnostic testReference testNumber of confirmed VLSensitivityNumber
visceral leishmaniasis 21394 diagnosis.10.1371/journal.pntd.0000584.t002Table 2Main characteristics of diagnostic tests for canine visceral leishmaniasis in Latin America.CountryDiagnostic testReference testNumber of confirmed VLSensitivityNumber and type
visceral leishmaniasis 26917 treatment.10.1371/journal.pntd.0000584.t003Table 3Main characteristics of selected studies reporting treatment of human visceral leishmaniasis in Latin America.CountryType of studyNumber of subjectsMean patient age (years)Treatment interventionsDose
visceral leishmaniasis 31153 Medline/PubMed using the search strategy cited above. The LILACS search was performed using the term visceral leishmaniasis because no document was retrieved when using the PubMed approach. The LILACS search was less specific
visceral leishmaniasis 39940 4.10.1371/journal.pntd.0000584.t004Table 4Main characteristics of selected studies reporting effects of control interventions against visceral leishmaniasis in Latin America.Country and periodStudy settingInterventionComparisonNumber of subjects in intervention

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