Epidemiological and clinical aspects of autoimmune thyroid diseases in children with Down's syndrome.

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Term Occurence Count Dictionary
hyperthyroidism 4 endocrinologydiseases
hypothyroidism 4 endocrinologydiseases
methimazole 4 endocrinologydiseasesdrugs
thyroiditis 4 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
methimazole 7683 median TSH receptor autoantibody (TRAB) serum levels did not differ in the two groups and the initial methimazole dosage that was needed in DS patients at the start of therapy, was not different from the one employed
methimazole 9636 pharmacological treatment. In fact, DS patients exhibited both lower relapse rates during the first methimazole cycle and higher remission rates after definitive methimazole withdrawal [[16]]. Furthermore, the methimazole
methimazole 9698 lower relapse rates during the first methimazole cycle and higher remission rates after definitive methimazole withdrawal [[16]]. Furthermore, the methimazole dosages which were needed to maintain euthyroidism under
methimazole 9746 methimazole cycle and higher remission rates after definitive methimazole withdrawal [[16]]. Furthermore, the methimazole dosages which were needed to maintain euthyroidism under treatment were lower in DS group [[16]]. It
Select Disease Character Offset Disease Term Instance
hyperthyroidism 6174 presentation in children and adolescents without DS are known to range from overt hypothyroidism to overt hyperthyroidism [[25]]. The biochemical picture that is detected most often, at HT diagnosis, is euthyroidism, followed
hyperthyroidism 6385 followed by either overt or subclinical hypothyroidism (SH) or, occasionally, overt and subclinical hyperthyroidism [[26]].By contrast, in DS children the most common biochemical pattern, at HT presentation, is by far
hyperthyroidism 6558 biochemical pattern, at HT presentation, is by far SH, followed by overt hypothyroidism, euthyroidism and hyperthyroidism , in decreasing order [[17]]. The prevalence of euthyroidism, at HT diagnosis, is significantly lower
hyperthyroidism 8648 a hormonal pattern compatible with thyroid dysfunctions: either SH or overt hypothyroidism or overt hyperthyroidism (Fig. 2). A deterioration of thyroid function over time was also observed in another longitudinal study
hypothyroidism 6150 function patterns at HT presentation in children and adolescents without DS are known to range from overt hypothyroidism to overt hyperthyroidism [[25]]. The biochemical picture that is detected most often, at HT diagnosis,
hypothyroidism 6325 that is detected most often, at HT diagnosis, is euthyroidism, followed by either overt or subclinical hypothyroidism (SH) or, occasionally, overt and subclinical hyperthyroidism [[26]].By contrast, in DS children the
hypothyroidism 6525 DS children the most common biochemical pattern, at HT presentation, is by far SH, followed by overt hypothyroidism , euthyroidism and hyperthyroidism, in decreasing order [[17]]. The prevalence of euthyroidism, at HT
hypothyroidism 8624 after HT presentation, a hormonal pattern compatible with thyroid dysfunctions: either SH or overt hypothyroidism or overt hyperthyroidism (Fig. 2). A deterioration of thyroid function over time was also observed
thyroiditis 653 According to recent reports, DS children are, per se, more exposed to the risk of both Hashimoto’s thyroiditis (HT) and Graves’ disease (GD), irrespective of other concomitant risk factors, such as female gender
thyroiditis 1661 features of DS children is their susceptibility toward several autoimmune diseases, such as Hashimoto’s thyroiditis (HT), Graves’ disease (GD), type 1 diabetes, celiac disease, alopecia, vitiligo and idiopathic arthritis
thyroiditis 6837 1Prevalence rates (%) of the biochemical pictures of thyroid function found, at diagnosis of Hashimoto’s thyroiditis (HT), in two cohorts of HT children with (Group A) or without Down’s syndrome (Group B) (according
thyroiditis 9203 rates (%) of the biochemical pictures of thyroid function found, both at diagnosis of Hashimoto’s thyroiditis (HT) and 5 years later, in a cohort of 146 children with Down’s syndrome (according to the results

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