Acid Balance, Dietary Acid Load, and Bone Effects-A Controversial Subject.

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Term Occurence Count Dictionary
calcium carbonate 1 endocrinologydiseasesdrugs
osteoporosis 13 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
calcium carbonate 3664 (Cl), bicarbonate (HCO3))) in the form of alkaline salts of calcium (e.g., calcium hydroxyapatite, calcium carbonate ). The concept that such bone base can be released to neutralize part of the dietary net acid load might
Select Disease Character Offset Disease Term Instance
osteoporosis 1103 question of whether decades of eating a high acid diet might contribute to the loss of bone mass in osteoporosis . If this idea is true, then additional alkali ingestion in the form of net base-producing foods or alkalinizing
osteoporosis 1793 increasing age, then review the evidence for and against the usefulness of alkali therapy as a treatment for osteoporosis , and finally suggest a way of reconciling these two opposing points of view.1. IntroductionIn western
osteoporosis 1994 IntroductionIn western society, aging is accompanied by a loss of bone mass indicative of the bone disorder, osteoporosis . Osteoporosis is a condition in which bone resorption outpaces bone formation, leading to a combination
osteoporosis 2196 a combination of progressive loss of bone mass and destruction of bone architecture. The idea that osteoporosis might in part be due to dietary intake of acid precursors in excess of base (bicarbonate) precursors
osteoporosis 4191 question of whether decades of eating a high acid diet might contribute to the loss of bone mass in osteoporosis . If this idea is true, then additional alkali ingestion in the form of net base-producing foods or alkalinizing
osteoporosis 4907 increasing age, then review the evidence for and against the usefulness of alkali therapy as a treatment for osteoporosis and finally suggest a way of reconciling these two opposing points of view.2. Acid BalanceBalance in
osteoporosis 9166 the Alkali Replacement for Prevention of Osteoporosis TheoryProponents of the alkali treatment for osteoporosis theory argue that in vitro studies demonstrate that large increases in system acid levels first activate
osteoporosis 9760 ability to completely regulate acid-base balance, might become a clinically significant contributor to osteoporosis . In healthy humans, the normal range for blood pH is between 7.35 and 7.45 [[22]]. The in vitro studies
osteoporosis 10747 receptor OGR-1, found in both osteoblasts and osteoclasts [[24]].Proponents of the alkali therapy for osteoporosis treatment then cite human studies that support this hypothesis [[25],[26],[27],[28],[29]]. These studies
osteoporosis 16244 are eliminated in some unknown and therefore unmeasured form.The opponents of the alkali therapy for osteoporosis treatment cite other supporting human studies [[36],[37],[38],[39],[40]]. These studies include meta-analyses
osteoporosis 20004 Multicentre Osteoporosis Study (CaMOS) which examined associations between urine acid excretion and osteoporosis [[39]]. Adjusting for confounders, the CaMOS study demonstrated no correlations of either urine pH or
osteoporosis 20381 occurrence of fragility fractures as the outcome measures, which are superior clinical outcomes measures of osteoporosis relative to the measurement of urine calcium changes. The authors used urine to measure the diet acid
osteoporosis 26935 would not be a readily detectable factor in altering bone mineral density leading to the development of osteoporosis . Other factors such as age, gender, race, and immobility are quantitatively more major factors in determining

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