Liquid Biopsy in Endometrial Cancer: New Opportunities for Personalized Oncology

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Annotation Summary

Term Occurence Count Dictionary
endometrial carcinoma 5 endocrinologydiseases
obesity 1 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Select Disease Character Offset Disease Term Instance
endometrial carcinoma 20188 Endothelial progenitor cell numbers (CD34, VEGFR2/KDR) in the peripheral blood of women with early endometrial carcinoma were significantly augmented compared with those of healthy control women, while circulating endothelial
endometrial carcinoma 20563 features have been demonstrated for the presence of disseminated tumour cells (DTC) in the bone marrow of endometrial carcinoma patients [[44],[45]].3.3. Cell free DNA (cfDNA)Changes in circulating cell-free DNA (cfDNA) levels have
endometrial carcinoma 22604 including 149 cervical squamous cell carcinoma and endocervical adenocarcinoma and 401 uterine corpus endometrial carcinoma [[39]]. This test is based on copy number variations (CNVs) of the cancer founding clone, modelling
endometrial carcinoma 28734 PGAM2; KPYM, MMP9, to identify the disease; CTNB1, XPO2, and CAPG to discriminate between endometrioid endometrial carcinoma s (EEC) and serous endometrial carcinoma (SEC)[[25],[26]]Targeted SequencingDiagnosisPTEN, PIK3CA, CTNNB1,
endometrial carcinoma 28774 CTNB1, XPO2, and CAPG to discriminate between endometrioid endometrial carcinomas (EEC) and serous endometrial carcinoma (SEC)[[25],[26]]Targeted SequencingDiagnosisPTEN, PIK3CA, CTNNB1, TP53, FGFR2, KRAS, CDKN2A (most common
obesity 12129 an increasing incidence in developed countries [[1]]. Risk factors for EC include age ≥40 years, obesity , diabetes, hypertension, estrogen using, tamoxifen treatment, and family history of malignant tumours.

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