Alpha lipoic acid combined with epalrestat: a therapeutic option for patients with diabetic peripheral neuropathy

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Term Occurence Count Dictionary
diabetic neuropathy 5 endocrinologydiseases
hyperglycemia 1 endocrinologydiseases
diabetes mellitus 5 endocrinologydiseases

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Select Disease Character Offset Disease Term Instance
diabetes mellitus 2818 finding.IntroductionDiabetic neuropathy (DN) is a very common, symptomatic, long-term complication of diabetes mellitus , affecting nearly 50% of patients with type 1 and/or type 2 diabetes.[1] According to International
diabetes mellitus 5881 satisfied the following criteria were selected. 1) Patients: Patients with DPN. The diagnostic criteria for diabetes mellitus and its complications in the trials were in accordance with the criteria of the 1999 World Health Organization
diabetes mellitus 25033 #35 or #36 or #37#39blind [MeSH]#40#16 and #28 and #33 and #38 and #39Search strategy used in CNKI#1 diabetes mellitus [MeSH]#2peripheral neuropathy [MeSH]#3#1 and #2#4diabetes mellitus [Full text]#5peripheral neuropathy
diabetes mellitus 25100 #39Search strategy used in CNKI#1diabetes mellitus [MeSH]#2peripheral neuropathy [MeSH]#3#1 and #2#4 diabetes mellitus [Full text]#5peripheral neuropathy [Full text]#6#4 and #5#7diabetes mellitus [key word]#8peripheral
diabetes mellitus 25177 neuropathy [MeSH]#3#1 and #2#4diabetes mellitus [Full text]#5peripheral neuropathy [Full text]#6#4 and #5#7 diabetes mellitus [key word]#8peripheral neuropathy [key word]#9#7 and #8#10diabetic peripheral neuropathy [MeSH]#11diabetic
diabetic neuropathy 7936 or “lipoic acid” and “diabetic peripheral neuropathy” or “peripheral neuropathy” or “ diabetic neuropathy ” or “DPN” and “randomized controlled trial” or “randomized” and “blind” were used;
diabetic neuropathy 8241 mesh terms were used, with no restriction on subheadings: ((diabetic AND peripheral neuropathy) OR ( diabetic neuropathy OR diabetic peripheral neuropathy)) AND ((thioctic acid) OR (thioctic AND acid) OR (lipoic acid) OR
diabetic neuropathy 24399 Fields]#18peripheral neuropathy [All Fields]#19#17 and #18#20neuropathy [All Fields]#21#17 and #20#22 diabetic neuropathy [All Fields]#23diabetic peripheral neuropathy [All Fields]#24diabetic neuropathy [MeSH]#25diabetic peripheral
diabetic neuropathy 24480 Fields]#21#17 and #20#22diabetic neuropathy [All Fields]#23diabetic peripheral neuropathy [All Fields]#24 diabetic neuropathy [MeSH]#25diabetic peripheral neuropathy [MeSH]#26diabetic neuropathy [TIAB]#27diabetic peripheral neuropathy
diabetic neuropathy 24549 peripheral neuropathy [All Fields]#24diabetic neuropathy [MeSH]#25diabetic peripheral neuropathy [MeSH]#26 diabetic neuropathy [TIAB]#27diabetic peripheral neuropathy [TIAB]#28#19 or #21 or #22 or #23 or #24 or #25 or #26 or #27#29epalrestat
hyperglycemia 3310 associated with high morbidity, mortality, and diminished quality of life.[5] Diabetic damage due to hyperglycemia and metabolic imbalance – primarily, oxidative stress – may appear in the neurons (axons or myelin

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