The Differential Effects of Eicosapentaenoic Acid and Docosahexaenoic Acid on Cardiometabolic Risk Factors: A Systematic Review.

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obesity 5 endocrinologydiseases

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obesity 7558 subjects, treated hypertensive type 2 diabetics, mildly hyperlipidaemic men, and subjects with abdominal obesity and low-grade inflammation, as well as healthy subjects. Two studies focused on male subjects only [[49],[50]].
obesity 17812 (−15%) for DHA compared to corn oil placebo in subjects with subclinical inflammation and abdominal obesity , whilst EPA resulted in a significant decrease in plasma IL-6 only (−13%) [[52]]. When compared with
obesity 42421 [[54]]Double-blind randomised controlled crossover study with 9 week washout.Healthy subjects with abdominal obesity and low-grade inflammationn = 121 (EPA)n = 123 (DHA)n = 125 (corn oil)n = 125 (total)2.7 (EPA) 2.7 (DHA)3.0
obesity 47225 vs. DHA on Blood Lipids and LipoproteinsAllaire et al., 2016 [[52]]Healthy subjects with abdominal obesity and low-grade inflammationCorn oil↓ Triglycerides (−12%, p < 0.0001)↑ LDL cholesterol (+2%, p
obesity 53841 Inflammatory MarkersAllaire et al., 2016 [[52]], Vors et al., 2017 [[54]]Healthy subjects with abdominal obesity and low-grade inflammationCorn oil↓ IL-6 (−13%, p = 0.03)No significant effect on IL-18, CRP, TNF-α

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