Decreasing the Cholesterol Burden in Heterozygous Familial Hypercholesterolemia Children by Dietary Plant Stanol Esters

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Term Occurence Count Dictionary
familial hypercholesterolemia 6 endocrinologydiseases
simvastatin 2 endocrinologydiseasesdrugs

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Select Drug Character Offset Drug Term Instance
simvastatin 10404 of the daily consumption of rapeseed oil margarine (2.24 g/day stanols) on top of 20 mg or 40 mg of simvastatin [[36]]. In this six-week study, the baseline serum LDL-C level decreased significantly by about 20%,
simvastatin 10614 20%, i.e., from 4.09 ± 0.18 mmol/L to 3.27 ± 0.18 mmol/L (SE), and this decrease was independent of simvastatin dose. The effectiveness of a stanol ester diet can be understood when considering the homeostatic control
Select Disease Character Offset Disease Term Instance
familial hypercholesterolemia 565 covers the current knowledge about plant stanol esters as a dietary treatment option for heterozygous familial hypercholesterolemia (he-FH) children. The current estimation of the prevalence of he-FH is about one out of 200–250 persons.
familial hypercholesterolemia 2037 discusses the current knowledge about plant stanol esters as a dietary treatment option for heterozygous familial hypercholesterolemia (he-FH) children. Since the majority of reviews on dietary phytosterols (the common term for plant sterol
familial hypercholesterolemia 3044 forms.It is estimated that as many as 4.5 million people in Europe suffer from the heterozygous form of familial hypercholesterolemia [[5]]. Patients with he-FH have a highly elevated lifelong serum LDL-cholesterol (LDL-C) level, and,
familial hypercholesterolemia 20252 is estimated that as many as 4.5 million people in Europe alone suffer from the heterozygous form of familial hypercholesterolemia , and accordingly, the numbers of he-FH children must also be very high. Quantitative computed tomography
familial hypercholesterolemia 21279 margarine on serum non-cholesterol sterol proportions (100 mmol/mol of cholesterol) among 24 heterozygous familial hypercholesterolemia (he-FH) children aged 3 to 13 years [[36]]. Stanol ester margarine reduced the ratios of serum campesterol,
familial hypercholesterolemia 22645 21%.nutrients-10-01842-t001_Table 1Table 1Effect of dietary stanol ester margarine on serum lipids among 24 heterozygous familial hypercholesterolemia (FH)–North Karelia (FH-NK) children [[36]].LipidsBaselineStanol Ester MargarineDifference, %pTC7.41

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