Sleep apnea and type 2 diabetes.

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Annotation Summary

Term Occurence Count Dictionary
obesity 5 endocrinologydiseases
Insulin 1 endocrinologydiseasesdrugs
diabetes mellitus 1 endocrinologydiseases
glucose intolerance 1 endocrinologydiseases

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Select Drug Character Offset Drug Term Instance
Insulin 11508 the effect of CPAP on HbA1c is restricted to patients with good CPAP adherence (≥4 h/night)20, 21. Insulin resistance and sensitivityReducing insulin resistance is essential for improving glucose metabolism,
Select Disease Character Offset Disease Term Instance
diabetes mellitus 6358 end‐organ morbidity. In a meta‐analysis of cross‐sectional studies, the odds ratio (OR) and 95% CI of diabetes mellitus in snorers compared with non‐snorers was 1.37 (1.20–1.57), although it is likely there are also
glucose intolerance 21501 trend)41.In a study carried out in Toon, Japan, the adjusted ORs (95% CI) for impaired fasting glucose, glucose intolerance and diabetes for participants with ODI ≥15.0 events/h were 1.27 (0.72–2.23), 1.69 (1.03–2.76)
obesity 2795 adrenal axis and changes in adipokine profiles, both of which usually lead to fat accumulation and obesity 1. Using animal models, Zhang et al.2 and Xu et al.3 established that intermittent hypoxia causes insulin
obesity 3181 suggest that sleep‐disordered breathing and type 2 diabetes are associated, independent of aging and obesity .Figure 1Pathophysiological pathway between obstructive sleep apnea and diabetes. CPAP, continuous positive
obesity 6032 have diabetes1. These data clearly show that OSA and diabetes are associated, independent of aging and obesity .Snoring and type 2 diabetesSnoring is caused by airflow through a narrowing upper airway, and is considered
obesity 13445 insulin sensitivity was found among obese patients than among non‐obese patients, suggesting that obesity is also an important determinant of insulin resistance, similar to the previous studies with negative
obesity 19321 resistance, but it might be difficult to achieve such a good adherence for all OSA patients. Second, as obesity , lifestyle and dietary behaviors also contribute to glucose metabolism and insulin resistance (Figure

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