A Mini Review on Antidiabetic Properties of Fermented Foods

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Annotation Summary

Term Occurence Count Dictionary
hyperglycemia 3 endocrinologydiseases
hyperlipidemia 1 endocrinologydiseases
lactose intolerance 1 endocrinologydiseases
obesity 1 endocrinologydiseases
Insulin 14 endocrinologydiseasesdrugs
diabetes mellitus 1 endocrinologydiseases

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Review

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Select Drug Character Offset Drug Term Instance
Insulin 27555 foods.Model SystemStudy MaterialFindingsReferenceSTZ-induced diabetic ratsFermented tea beverage↓ HbA1c↑ Insulin , hemoglobin and tissue glycogen.Normalized the activities of glucose-6-phosphatase, fructose-1,6-bisphosphatase,
Insulin 27784 hexokinase[[15]]STZ-induced diabetic miceFermented food paste (Xeniji™)↓ Blood glucose↓ Leptin↑ Insulin sensitivity↑ Lipid and glucose metabolism↓ Proinflammatory cytokines↓ NF-κB and iNOS gene expression↓
Insulin 29414 Glutathione level[[29]]KK-Ay/TaJcl miceFermented noni↓ HbA1c↓ Blood glucose↓ Serum triglyceride, LDL↑ Insulin sensitivity[[30]]db/db MiceFermented soybean↓ HbA1c↓ Blood glucose↑ Plasma insulin level[[31]]Sprague–Dawley
Insulin 29668 (Chungkookjang), and Jerusalemartichoke (Helianthus tuberosus L.)↓ Visceral fat↑ Glucose tolerance↑ Insulin secretion↓ Hepatic glucose↓ Triglyceride↑ Insulin sensitivity↑ β-cell mass[[32]]Alloxan-induced
Insulin 29724 L.)↓ Visceral fat↑ Glucose tolerance↑ Insulin secretion↓ Hepatic glucose↓ Triglyceride↑ Insulin sensitivity↑ β-cell mass[[32]]Alloxan-induced diabetic miceFermented mungbean extracts↓ Cholesterol↓
Insulin 29864 mass[[32]]Alloxan-induced diabetic miceFermented mungbean extracts↓ Cholesterol↓ Triglyceride ↓ LDL↑ Insulin secretion ↑ Antioxidant level[[33]]Alloxan-induced diabetic ratsFermentedRhynchosia nulubilis (Yak-Kong)↑
Insulin 30193 factors↓ Malondialdehyde[[34]]KK-Ay diabetic miceFermented green tea↓ HbA1c↓ Glucose level↓ Insulin resistance↑ Glycolysis associated gene expressions[[35]]db/db mouseFermented green tea↓ Body weight↓
Insulin 30546 fat↑Adiponectin↓ Serum leptin levels↓ Pancreatic weight↓ Pancreatic islet numbers↓ Blood glucose levels↑ Insulin level↓ LDL↑ HDL↓ Triglyceride↓ Serum AST and ALT levels↓ Steatohepatitis regions↓ Hepatocyte
Insulin 31202 rice↓ HbA1c↓ Glucose level↑ Body weight↑ HDL↓ LDL↓ VLDL↓ Cholesterol ↓ Triglyceride↑ Insulin level↓ Urea↓ Creatinine ↓ Uric acid↓ BUN↑ Total protein↑ SOD, CAT, GSH, and GPX activities[[39]]db/db
Insulin 31408 activities[[39]]db/db miceFermented milk with conjugatedlinoleic acid↓ Body weight ↓ Blood glucose↑ Insulin , and leptin levelImproved the glucose and insulin tolerance.↓ Cholesterol↓ Triglycerides↓ LDL↑
Insulin 31638 db/db miceFermented purple Jerusalem artichoke (Helianthus tuberosus L.) extract↓ Blood glucose↑ Insulin ↑ HDL↓ Cholesterol↓ Triglycerides↓ Non-essential fatty acids↓ α-glucosidase activity[[41]]STZ-induced
Insulin 31942 Food consumption↓ Cholesterol↓ Triglycerides↓ BUN↓ LDL↓ Creatinine↓ Malondialdehyde↑ Insulin ↑ SOD[[42]]C57BL/6 miceFermented Moringa oleifera Lam↑ Glucose tolerance↓ Glucose intolerance↓
Insulin 33321 prediabetes (n = 21)Kimchi (fresh and fermented)↓ Body mass, body mass index, and waist perimeter.↓ Insulin resistance, and blood pressure.↑ Insulin sensitivity, QUICKI and disposition index.[[7]]Hypertensive
Insulin 33364 fermented)↓ Body mass, body mass index, and waist perimeter.↓ Insulin resistance, and blood pressure.↑ Insulin sensitivity, QUICKI and disposition index.[[7]]Hypertensive and type 2 diabetic patients (n = 41)Korean
Select Disease Character Offset Disease Term Instance
diabetes mellitus 5015 food. Recent scientific reports have proposed that the supplementation of fermented foods diminish the diabetes mellitus (DM)-associated health consequences [[15],[16],[17]]. The current review provides the cumulative information
hyperglycemia 1849 the development of complementary and alternative medicines to improve the treatment strategies for hyperglycemia .1. IntroductionFermented foods (FFs) are the product of the microbial conversion of raw food materials.
hyperglycemia 17286 improved the overall health status of type 2 diabetic db/db mouse by diminishing the consequences of hyperglycemia , hyperlipidemia, and obesity [[36]].The supplementation of fermented soy permeates (FSP; 100 mg/day)
hyperglycemia 25834 which aids in the development and marketing of FF-based alternative remedies for the management of hyperglycemia .Figure 1A Schematic representation of possible mechanism of anti-diabetic activity of bioactive compounds
hyperlipidemia 17301 overall health status of type 2 diabetic db/db mouse by diminishing the consequences of hyperglycemia, hyperlipidemia , and obesity [[36]].The supplementation of fermented soy permeates (FSP; 100 mg/day) for three weeks
lactose intolerance 4562 galactosidases producing microbes via FFs help people consume dairy products without any consequences of lactose intolerance , [[2]] and it has been reviewed that FFs are a multisource of bioactive microbes with multiple health-promoting
obesity 17321 of type 2 diabetic db/db mouse by diminishing the consequences of hyperglycemia, hyperlipidemia, and obesity [[36]].The supplementation of fermented soy permeates (FSP; 100 mg/day) for three weeks significantly

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