Association of maternal diabetes with autism spectrum disorders in offspring: A systemic review and meta-analysis.

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diabetes mellitus 2 endocrinologydiseases
obesity 3 endocrinologydiseases

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diabetes mellitus 1450 among diabetic mothers compared with non-diabetic mothers.Maternal diabetes, especially gestational diabetes mellitus , is associated with ASDs in offspring based on a limited number of convincing case-control studies.
diabetes mellitus 3545 prospective birth study in 2016 (N = 2743 mother–child pair) showed a weak association of gestational diabetes mellitus (GDM) with ASD (hazard ratio [HR] 1.86; 95% confidence interval [CI] 0.92–3.76) after adjusting crucial
obesity 12633 risk of ASD in offspring and this impact was independent of crucial covariates such as maternal age, obesity , and gestational week.[[23]] Another retrospective study recruited >40,000 participants and consistently
obesity 17769 noteworthy that some of the variables are strongly correlated to risk of ASD. For example, maternal obesity was related to an increased risk of ASD in offspring, according to recent meta-analytic studies.[[43],[44]]
obesity 17931 according to recent meta-analytic studies.[[43],[44]] Furthermore, the risk of ASD was greater when obesity and diabetes occurred concomitantly.[[21]] So studies that took potential covariates into account were

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